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  1. 120921
    “…Assignment was done with computer-generated randomisation in permuted blocks of 20, stratified by centre and age younger or older than 6 months. …”
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    Daily co-trimoxazole prophylaxis to prevent mortality in children with complicated severe acute malnutrition: a multicentre, double-blind, randomised placebo-controlled trial
  2. 120922
    “…Patients were randomly allocated (1:1:1:1) using a secure web-based server to receive 2 g EPA-free fatty acid (FFA) per day (either as the FFA or triglyceride), 300 mg aspirin per day, both treatments in combination, or placebo for 12 months using random permuted blocks of randomly varying size, and stratified by BCSP site. …”
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    Eicosapentaenoic acid and aspirin, alone and in combination, for the prevention of colorectal adenomas (seAFOod Polyp Prevention trial): a multicentre, randomised, double-blind, placebo-controlled, 2 × 2 factorial trial
  3. 120923
    “…Pyruvate addition for mPTP blocking strongly reduced SSM swelling in IR40/30 (relative AUC, ± pyruvate; IR0/30: 1.00 vs. 0.61, IR15/30: 1.68 vs. 1.00, IR30/30: 1.42 vs. 0.75, IR40/30: 1.97 vs. 0.85; p < 0.01). …”
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    Ischemia time impacts on respiratory chain functions and Ca(2+)-handling of cardiac subsarcolemmal mitochondria subjected to ischemia reperfusion injury
  4. 120924
    “…INTRODUCTION: Glutaminase inhibitors target cancer cells by blocking the conversion of glutamine to glutamate, thereby potentially interfering with anaplerosis and synthesis of amino acids and glutathione. …”
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    Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer
  5. 120925
    “…Participants were randomly assigned (2:1), with allocation by use of computer-generated random permuted blocks of six, to either cediranib (30 mg orally, once daily) or matching placebo tablets for 24 weeks. …”
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    Cediranib in patients with alveolar soft-part sarcoma (CASPS): a double-blind, placebo-controlled, randomised, phase 2 trial
  6. 120926
    “…Atrial cells were obtained from consenting patients undergoing heart surgery, as well as from rabbits. I (CaL) was blocked with nifedipine and then a hybrid patch clamp/mathematical‐modelling technique, ‘dynamic clamping’, was used to record action potentials at the same time as injecting an artificial, modifiable, I (CaL) (I (CaL,D‐C)). …”
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    Dynamic clamping human and rabbit atrial calcium current: narrowing I (CaL) window abolishes early afterdepolarizations
  7. 120927
    “…METHODS AND FINDINGS: This open cluster-randomized trial was conducted in 22 PHCs in six tribal blocks of Bharuch and Narmada districts in India. …”
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    mHealth intervention “ImTeCHO” to improve delivery of maternal, neonatal, and child care services—A cluster-randomized trial in tribal areas of Gujarat, India
  8. 120928
    “…Participants were randomly allocated (1:1) by computerised central randomisation with permuted blocks (size four and six), stratified by centre and risk group, to conventionally fractionated or moderately hypofractionated radiotherapy (78 Gy in 39 fractions over 7·8 weeks or 62 Gy in 20 fractions over 4 weeks, respectively) or stereotactic body radiotherapy (36·25 Gy in five fractions over 1–2 weeks). …”
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    Intensity-modulated fractionated radiotherapy versus stereotactic body radiotherapy for prostate cancer (PACE-B): acute toxicity findings from an international, randomised, open-label, phase 3, non-inferiority trial
  9. 120929
    “…All the teeth were divided equally among the subgroups and were mounted on color-coded acrylic blocks to aid in identification. Group I was bonded with Transbond XT Light Cure Adhesive (3M Unitek Orthodontic Products, Monrovia, California) and Group II was bonded using Phase II two-paste system (Reliance Orthodontic Products, Itasca, Illinois). …”
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    A Comparative Study of Shear Bond Strength of Direct Bonding System with and without a Liquid Primer: An In Vitro Study
  10. 120930
    “…MG132 and DHB significantly blocked the MeHg-induced decrease in [Formula: see text] expression ([Formula: see text]). …”
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    Acute Methylmercury Exposure and the Hypoxia-Inducible [Formula: see text] Signaling Pathway under Normoxic Conditions in the Rat Brain and Astrocytes in Vitro
  11. 120931
    “…Finally, we revealed that augmenting adenosine effects by blocking adenosine deamination with deoxycoformycin decreased aortic valve thickness and reduced markers of calcification via adenosine-dependent pathways in a mouse model of CAVD. …”
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    Nucleotide ecto-enzyme metabolic pattern and spatial distribution in calcific aortic valve disease; its relation to pathological changes and clinical presentation
  12. 120932
    “…To analyze the temporal dynamics of social hierarchy formation and maintenance, a total of 102 weaned pigs (47 females and 55 barrows) were selected and blocked by sex and body weight. The pigs were mixed into 10 single-sex pens (10 to 11 pigs/pen) avoiding original littermates. …”
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    Reestablishment of Social Hierarchies in Weaned Pigs after Mixing
  13. 120933
    “…Twenty-eight newborn Holstein heifer calves from the university herd and 8 newborn Holstein heifer calves from a commercial herd were blocked by birth and herd into 1 of 4 treatments: conventional [20% crude protein (CP), 20% fat] milk replacer (MR; treatment C) with (1) or without (0) human visitation, or a higher plane of MR nutrition (28% CP, 20% fat) regimen (treatment A) with (1) or (0) without human visitation. …”
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    Effects of human visitation on calf growth and performance of calves fed different milk replacer feeding levels
  14. 120934
    “…Further study revealed that the activation of the PI3K/Akt/mTOR pathway induced by HSV-2 infection may result in the blocked autophagic flux and inhibited autophagosome and autolysosome formation. …”
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    The Chinese herbal prescription JZ-1 induces autophagy to protect against herpes simplex Virus-2 in human vaginal epithelial cells by inhibiting the PI3K/Akt/mTOR pathway
  15. 120935
    “…Each episode was randomly allocated independently of previous treatment from a computer-generated list of random numbers in blocks of ten (generated at the Pharmacy of Glostrup). …”
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    Azithromycin for episodes with asthma-like symptoms in young children aged 1–3 years: a randomised, double-blind, placebo-controlled trial
  16. 120936
    “…METHODS: We did an open-label, non-inferiority, randomised (1:1 with blocks of six), multicentre, phase 3 clinical trial comparing fully oral RC8 with RS8 in patients with early, limited Buruli ulcer lesions. …”
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    Rifampicin and clarithromycin (extended release) versus rifampicin and streptomycin for limited Buruli ulcer lesions: a randomised, open-label, non-inferiority phase 3 trial
  17. 120937
    “…Despite the octreoscan positivity, cortisol production was not appreciably blocked by octreotide but was well controlled by metyrapone. …”
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    SUN-907 Dual Ectopic Gastrin and ACTH Secretion Leading to Combined Zollinger-Ellison Syndrome and Cushing’s Syndrome in a Patient with Metastatic Neuroendocrine Pancreatic Tumor
  18. 120938
    “…The impact on serval welfare in relation to such programs has not been investigated to date, and the aim of this study was to assess short-term welfare effects of varying levels of visitor interaction in two captive servals. Weekly blocks of four different treatments were imposed three times on each animal over 12 weeks, and the treatments involved (1) Presentations (serval undertaking a routine training session in a designated presentation space, typically attracting high visitor numbers), (2) Behind-the-scenes (BTS, a close encounter allowing a small group of visitors to interact closely with the cat in its enclosure), (3) Presentations and BTS combined, and (4) No visitor interaction. …”
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    The Effect of Behind-The-Scenes Encounters and Interactive Presentations on the Welfare of Captive Servals (Leptailurus serval)
  19. 120939
    “…SNHG6 upregulated FUBP1 expression by sponging miR-26a-5p. Silencing SNHG6 blocked the growth of PC in vivo. CONCLUSION: Silencing SNHG6 might ameliorate PC through inhibition of FUBP1 by sponging miR-26a-5p, thus providing further supporting evidence for its use in PC treatment.…”
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    Long non-coding RNA small nucleolar RNA host gene 6 aggravates pancreatic cancer through upregulation of far upstream element binding protein 1 by sponging microRNA-26a-5p
  20. 120940
    “…The efficacy of insulin in blocking lipolysis and protein breakdown is lower after oral glucose loads vs the intravenous route. …”
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    Insulin sensitivity depends on the route of glucose administration
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