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121041por Conway, Eadaoin, Sweeney, Torres, Dowley, Alison, Vigors, Stafford, Ryan, Marion, Yadav, Supriya, Wilson, Jude, O’Doherty, John V.“…ABSTRACT: This study was conducted to examine the effects of varying selenium (Se) inclusion levels, in the form of Se-enriched mushroom powder (SeMP) and selenite, on post-weaning growth performance (Period 1; day 1–21), intestinal health and antioxidant capacity (Period 2; day 21–39). Weaned pigs were blocked according to live weight, sex and litter of origin and randomly assigned to the following experimental groups: basal (basal + selenite (0.3 ppm Se)); ZnO (basal + ZnO + selenite (0.3 ppm Se)); 0.15 SeMP (basal + SeMP (0.15 ppm Se)); 0.3 SeMP (basal + SeMP (0.3 ppm Se)) and 0.6 SeMP/Sel (basal + SeMP (0.3 ppm Se) + selenite (Sel) (0.3 ppm Se)) with eight replicates/experimental group. …”
Publicado 2022
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121042“…In view of the deficiency of epidemic prevention and control, it has improved China's public health legal system and blocked the loopholes in the criminal law of the People's Republic of China (hereinafter referred to as the criminal law). …”
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121043por Kanungo, Suman, Chatterjee, Pranab, Bavdekar, Ashish, Murhekar, Manoj, Babji, Sudhir, Garg, Richa, Samanta, Sandip, Nandy, Ranjan K, Kawade, Anand, Boopathi, Kangusamy, Kanagasabai, Kaliaperumal, Kamal, Vineet Kumar, Kumar, Velusamy Saravana, Gupta, Nivedita, Dutta, Shanta“…Randomisation was done using an online software by site in blocks of at least 12. The primary outcome was seroresponse to rotavirus vaccine, measured using rotavirus-specific serum IgA antibodies 4 weeks after the third dose. …”
Publicado 2022
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121044por Jain, Arad, Patel, Tushar P, Altman, Elizabeth K, Tugarinov, Nicol, Levi, Noah J, Elizondo, Diana M, Arner, Brooke E, Roberson, Robin B, Caron, Alexandre, Elmquist, Joel K, Yanovski, Jack A“…A liver-specific MC3R recovery model was generated by crossbreeding mice with a floxed transcriptionally blocked Mc3r (Mc3rtb/tb) to mice expressing albumin-Cre recombinase (Alb-Cre+/+). …”
Publicado 2022
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121045Vectorial capacity and TEP1 genotypes of Anopheles gambiae sensu lato mosquitoes on the Kenyan coastpor Bartilol, Brian, Omuoyo, Donwilliams, Karisa, Jonathan, Ominde, Kelly, Mbogo, Charles, Mwangangi, Joseph, Maia, Marta, Rono, Martin Kibet“…This, therefore, calls for the development of alternative approaches such as malaria transmission-blocking vaccines or gene drive systems. The thioester-containing protein 1 (TEP1) gene, which mediates the killing of Plasmodium falciparum in the mosquito midgut, has recently been identified as a promising target for gene drive systems. …”
Publicado 2022
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121046por Tripura, Rupam, von Seidlein, Lorenz, Sovannaroth, Siv, Peto, Thomas J, Callery, James J, Sokha, Meas, Ean, Mom, Heng, Chhouen, Conradis-Jansen, Franca, Madmanee, Wanassanan, Peerawaranun, Pimnara, Waithira, Naomi, Khonputsa, Panarasri, Jongdeepaisal, Monnaphat, Pongsoipetch, Kulchada, Chotthanawathit, Paphapisa, Soviet, Ung, Pell, Christopher, Duanguppama, Jureeporn, Rekol, Huy, Tarning, Joel, Imwong, Mallika, Mukaka, Mavuto, White, Nicholas J, Dondorp, Arjen M, Maude, Richard J“…Allocations were done according to a computer-generated randomisation schedule, and randomisation was in permuted blocks of size ten and stratified by village. Investigators and participants were not masked to drug allocation, but laboratory investigations were done without knowledge of allocation. …”
Publicado 2023
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121047por Clark, Tristan W, Beard, Kate R, Brendish, Nathan J, Malachira, Ahalya K, Mills, Samuel, Chan, Cathleen, Poole, Stephen, Ewings, Sean, Cortes, Nick, Nyimbili, Esther, Presland, Laura“…Participants were randomly assigned (1:1), using random permuted blocks of varying sizes (4, 6 and 8), to receive mPOCT for influenza or routine clinical care (control group). …”
Publicado 2021
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121048por Hara, Toshihiko, Kaneuji, Ayumi, Sonoda, Kazuhiko, Nakamura, Tetsuro, Fujii, Masanori, Takahashi, Eiji“…Beta-tricalcium phosphate blocks are inserted into the bone gap. The osteotomized wedge-shaped iliac bone is repositioned and fixed. …”
Publicado 2022
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121049por Blanco Garcia, Oscar Roberto“…\par A set of three cavities (IPA, IPB and IPC), two upstream and one downstream of the nominal IP and on top of separate blocks of piezo-electric movers, were installed and are used to measure the beam trajectory in the IP region, thus providing enough information to reconstruct the bunch position and angle at the IP. …”
Publicado 2015
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121050COVID-19 Vaccination Preferences Among Non-Chinese Migrants in Hong Kong: Discrete Choice Experimentpor Asim, Saba, Wang, Kailu, Nichini, Elena, Yip, Faustina Fu, Zhu, Liling, Fung, Hin Chung Eddy, Zeng, Yan, Fang, Zhilan, Cheung, Annie Wai-Ling, Wong, Eliza Lai-yi, Dong, Dong, Yeoh, Eng-Kiong“…The vaccination attributes included in 8 choice sets in each of the 4 blocks were vaccine brand, safety and efficacy, vaccine uptake by people around, professionals’ recommendation, vaccination venue, and quarantine exemption for vaccinated travelers. …”
Publicado 2023
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121051por Vandenberghe, Stefaan, Muller, Florence M., Withofs, Nadia, Dadgar, Meysam, Maebe, Jens, Vervenne, Boris, Akl, Maya Abi, Xue, Song, Shi, Kuangyu, Sportelli, Giancarlo, Belcari, Nicola, Hustinx, Roland, Vanhove, Christian, Karp, Joel S.“…Each panel consists of 14 × 20 monolithic BGO detector blocks that are 50 × 50 × 16 mm in size and are coupled to a readout with 6 × 6 mm SiPMs arrays. …”
Publicado 2023
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121052por Francica, Joseph R, Cai, Yingyun, Diallo, Seme, Rosenthal, Kim, Ren, Kuishu, Flores, Daniel J, Dippel, Andrew, Wu, Yuling, Chen, Xiaoru, Cantu, Erin, Choudhary, Rakesh, Sulikowski, Michal, Adissu, Hibret, Chawla, Bhavna, Kar, Swagata, van Dyk, Nydia, Oganesyan, Vaheh, Rajan, Saravanan, Ryan, Patricia C, Loo, Yueh-Ming, Cohen, Taylor, Esser, Mark T, Blair, Wade“…RESULTS: AZD3152 binds to a conserved epitope on the spike receptor binding domain and blocks ACE2 binding. AZD3152 potently neutralizes authentic viral variants (EC(50) range, 8.3 to 110.9 ng/mL) and SARS-CoV-2 pseudoviruses (EC(50) range of 3.2 to 25.0 ng/mL), including XBB.1.5. …”
Publicado 2023
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121053“…Co-administration of the anti-estrogen ICI blocked the effects of E1 and E2 on cell migration. …”
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121054por Mawet, Marie, Maillard, Catherine, Klipping, Christine, Zimmerman, Yvette, Foidart, Jean-Michel, Coelingh Bennink, Herjan J.T.“…In combination with drospirenone (DRSP) or levonorgestrel (LNG), E(4) blocks ovulation and has less effect on haemostatic biomarkers in comparison with ethinylestradiol (EE) combined with DRSP. …”
Publicado 2015
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121055por Jacobs, Ian J, Menon, Usha, Ryan, Andy, Gentry-Maharaj, Aleksandra, Burnell, Matthew, Kalsi, Jatinderpal K, Amso, Nazar N, Apostolidou, Sophia, Benjamin, Elizabeth, Cruickshank, Derek, Crump, Danielle N, Davies, Susan K, Dawnay, Anne, Dobbs, Stephen, Fletcher, Gwendolen, Ford, Jeremy, Godfrey, Keith, Gunu, Richard, Habib, Mariam, Hallett, Rachel, Herod, Jonathan, Jenkins, Howard, Karpinskyj, Chloe, Leeson, Simon, Lewis, Sara J, Liston, William R, Lopes, Alberto, Mould, Tim, Murdoch, John, Oram, David, Rabideau, Dustin J, Reynolds, Karina, Scott, Ian, Seif, Mourad W, Sharma, Aarti, Singh, Naveena, Taylor, Julie, Warburton, Fiona, Widschwendter, Martin, Williamson, Karin, Woolas, Robert, Fallowfield, Lesley, McGuire, Alistair J, Campbell, Stuart, Parmar, Mahesh, Skates, Steven J“…The trial management system confirmed eligibility and randomly allocated participants in blocks of 32 using computer-generated random numbers to annual multimodal screening (MMS) with serum CA125 interpreted with use of the risk of ovarian cancer algorithm, annual transvaginal ultrasound screening (USS), or no screening, in a 1:1:2 ratio. …”
Publicado 2016
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121056por Nadkarni, Abhijit, Weobong, Benedict, Weiss, Helen A, McCambridge, Jim, Bhat, Bhargav, Katti, Basavaraj, Murthy, Pratima, King, Michael, McDaid, David, Park, A-La, Wilson, G Terence, Kirkwood, Betty, Fairburn, Christopher G, Velleman, Richard, Patel, Vikram“…Participants were randomly allocated (1:1) by trained health assistants based at the primary health centres to enhanced usual care (EUC) alone or EUC combined with CAP, in randomly sized blocks of four to six, stratified by primary health centre, and allocation was concealed with use of sequential numbered opaque envelopes. …”
Publicado 2017
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121057por Cameron, David, Morden, James P, Canney, Peter, Velikova, Galina, Coleman, Robert, Bartlett, John, Agrawal, Rajiv, Banerji, Jane, Bertelli, Gianfilippo, Bloomfield, David, Brunt, A Murray, Earl, Helena, Ellis, Paul, Gaunt, Claire, Gillman, Alexa, Hearfield, Nicholas, Laing, Robert, Murray, Nicholas, Couper, Niki, Stein, Robert C, Verrill, Mark, Wardley, Andrew, Barrett-Lee, Peter, Bliss, Judith M“…The randomisation schedule was computer generated in random permuted blocks, stratified by centre, number of nodes involved (none vs one to three vs four or more), age (≤50 years vs >50 years), and planned endocrine treatment (yes vs no). …”
Publicado 2017
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121058por Maes, Bastiaan, Bosteels, Cedric, De Leeuw, Elisabeth, Declercq, Jozefien, Van Damme, Karel, Delporte, Anja, Demeyere, Bénédicte, Vermeersch, Stéfanie, Vuylsteke, Marnik, Willaert, Joren, Bollé, Laura, Vanbiervliet, Yuri, Decuypere, Jana, Libeer, Frederick, Vandecasteele, Stefaan, Peene, Isabelle, Lambrecht, Bart“…OBJECTIVES: The purpose of this study is to test the safety and effectiveness of individually or simultaneously blocking IL-6, IL-6 receptor and IL-1 versus standard of care on blood oxygenation and systemic cytokine release syndrome in patients with COVID-19 coronavirus infection and acute hypoxic respiratory failure and systemic cytokine release syndrome. …”
Publicado 2020
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121059por Stockmann, Helena, Keller, Theresa, Büttner, Stefan, Jörres, Achim, Kindgen-Milles, Detlef, Kunz, Julius Valentin, Leebmann, Josef, Spies, Claudia, Träger, Karl, Treskatsch, Sascha, Uhrig, Alexander, Willam, Carsten, Enghard, Philipp, Slowinski, Torsten“…Randomization is done in blocks by 4 stratified by including center. BLINDING (MASKING): The trial will be non-blinded for the clinicians and patients. …”
Publicado 2020
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121060por Vlaar, Alexander P J, de Bruin, Sanne, Busch, Matthias, Timmermans, Sjoerd A M E G, van Zeggeren, Ingeborg E, Koning, Rutger, ter Horst, Liora, Bulle, Esther B, van Baarle, Frank E H P, van de Poll, Marcel C G, Kemper, E Marleen, van der Horst, Iwan C C, Schultz, Marcus J, Horn, Janneke, Paulus, Frederique, Bos, Lieuwe D, Wiersinga, W Joost, Witzenrath, Martin, Rueckinger, Simon, Pilz, Korinna, Brouwer, Matthijs C, Guo, Ren-Feng, Heunks, Leo, van Paassen, Pieter, Riedemann, Niels C, van de Beek, Diederik“…We aimed to explore the potential benefit and safety of selectively blocking the anaphylatoxin and complement protein C5a with the monoclonal antibody IFX-1 (vilobelimab), in patients with severe COVID-19. …”
Publicado 2020
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