In vivo characterization of the critical interaction between the RNA exosome and the essential RNA helicase Mtr4 in Saccharomyces cerevisiae

por Sterrett, Maria C, Farchi, Daniela, Strassler, Sarah E, Boise, Lawrence H, Fasken, Milo B, Corbett, Anita H
Publicado 2023

Bortezomib-induced heat shock response protects multiple myeloma cells and is activated by heat shock factor 1 serine 326 phosphorylation

por Shah, Shardule P., Nooka, Ajay K., Jaye, David L., Bahlis, Nizar J., Lonial, Sagar, Boise, Lawrence H.
Publicado 2016

TGF-β causes Docetaxel resistance in Prostate Cancer via the induction of Bcl-2 by acetylated KLF5 and Protein Stabilization

por Li, Yixiang, Zhang, Baotong, Xiang, Lingwei, Xia, Siyuan, Kucuk, Omer, Deng, Xingming, Boise, Lawrence H., Dong, Jin-Tang
Publicado 2020

Ceramide kinase is required for a normal eicosanoid response and the subsequent orderly migration of fibroblasts

por Wijesinghe, Dayanjan S., Brentnall, Matthew, Mietla, Jennifer A., Hoeferlin, L. Alexis, Diegelmann, Robert F., Boise, Lawrence H., Chalfant, Charles E.
Publicado 2014

MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma

por Wang, Dongxue, Hashimoto, Hideharu, Zhang, Xing, Barwick, Benjamin G., Lonial, Sagar, Boise, Lawrence H., Vertino, Paula M., Cheng, Xiaodong
Publicado 2017

Dexamethasone treatment promotes Bcl-2-dependence in multiple myeloma resulting in sensitivity to Venetoclax

por Matulis, Shannon M., Gupta, Vikas A., Nooka, Ajay K., Von Hollen, Hayley, Kaufman, Jonathan L., Lonial, Sagar, Boise, Lawrence H.
Publicado 2015

Sustained antibody responses depend on CD28 function in bone marrow–resident plasma cells

por Rozanski, Cheryl H., Arens, Ramon, Carlson, Louise M., Nair, Jayakumar, Boise, Lawrence H., Chanan-Khan, Asher A., Schoenberger, Stephen P., Lee, Kelvin P.
Publicado 2011

BCL2-BH4 antagonist BDA-366 suppresses human myeloma growth

por Deng, Jiusheng, Park, Dongkyoo, Wang, Mengchang, Nooka, Ajay, Deng, Qiaoya, Matulis, Shannon, Kaufman, Jonathan, Lonial, Sagar, Boise, Lawrence H., Galipeau, Jacques, Deng, Xingming
Publicado 2016

Downregulation of PA28α induces proteasome remodeling and results in resistance to proteasome inhibitors in multiple myeloma

por Gu, Yanyan, Barwick, Benjamin G., Shanmugam, Mala, Hofmeister, Craig C., Kaufman, Jonathan, Nooka, Ajay, Gupta, Vikas, Dhodapkar, Madhav, Boise, Lawrence H., Lonial, Sagar
Publicado 2020

Low expression of pro-apoptotic Bcl-2 family proteins sets the apoptotic threshold in Waldenström Macroglobulinemia

por Gaudette, Brian T., Dwivedi, Bhakti, Chitta, Kasyapa S., Poulain, Stéphanie, Powell, Doris, Vertino, Paula, Leleu, Xavier, Lonial, Sagar, Chanan-Khan, Asher A., Kowalski, Jeanne, Boise, Lawrence H.
Publicado 2015

β adrenergic signaling regulates hematopoietic stem and progenitor cell commitment and therapy sensitivity in multiple myeloma

por Nair, Remya, Subramaniam, Vimal, Barwick, Benjamin G., Gupta, Vikas A., Matulis, Shannon M., Lonial, Sagar, Boise, Lawrence H., Nooka, Ajay K., Muthumalaiappan, Kuzhali, Shanmugam, Mala
Publicado 2022

Integrated Analysis of Whole-Genome Paired-End and Mate-Pair Sequencing Data for Identifying Genomic Structural Variations in Multiple Myeloma

por Yang, Rendong, Chen, Li, Newman, Scott, Gandhi, Khanjan, Doho, Gregory, Moreno, Carlos S, Vertino, Paula M, Bernal-Mizarchi, Leon, Lonial, Sagar, Boise, Lawrence H, Rossi, Michael, Kowalski, Jeanne, Qin, Zhaohui S
Publicado 2014

A MCP1 fusokine with CCR2-specific tumoricidal activity

por Rafei, Moutih, Deng, Jiusheng, Boivin, Marie-Noëlle, Williams, Patrick, Matulis, Shannon M, Yuan, Shala, Birman, Elena, Forner, Kathy, Yuan, Liangping, Castellino, Craig, Boise, Lawrence H, MacDonald, Tobey J, Galipeau, Jacques
Publicado 2011

Image-guided genomics of phenotypically heterogeneous populations reveals vascular signalling during symbiotic collective cancer invasion

por Konen, J., Summerbell, E., Dwivedi, B., Galior, K., Hou, Y., Rusnak, L., Chen, A., Saltz, J., Zhou, W., Boise, L. H., Vertino, P., Cooper, L., Salaita, K., Kowalski, J., Marcus, A. I.
Publicado 2017

Multivariant Transcriptome Analysis Identifies Modules and Hub Genes Associated with Poor Outcomes in Newly Diagnosed Multiple Myeloma Patients

por Adebayo, Olayinka O., Dammer, Eric B., Dill, Courtney D., Adebayo, Adeyinka O., Oseni, Saheed O., Griffen, Ti’ara L., Ohandjo, Adaugo Q., Yan, Fengxia, Jain, Sanjay, Barwick, Benjamin G., Singh, Rajesh, Boise, Lawrence H., Lillard, Jr., James W.
Publicado 2022

Multiple myeloma immunoglobulin lambda translocations portend poor prognosis

por Barwick, Benjamin G., Neri, Paola, Bahlis, Nizar J., Nooka, Ajay K., Dhodapkar, Madhav V., Jaye, David L., Hofmeister, Craig C., Kaufman, Jonathan L., Gupta, Vikas A., Auclair, Daniel, Keats, Jonathan J., Lonial, Sagar, Vertino, Paula M., Boise, Lawrence H.
Publicado 2019

Gene integrated set profile analysis: a context-based approach for inferring biological endpoints

por Kowalski, Jeanne, Dwivedi, Bhakti, Newman, Scott, Switchenko, Jeffery M., Pauly, Rini, Gutman, David A., Arora, Jyoti, Gandhi, Khanjan, Ainslie, Kylie, Doho, Gregory, Qin, Zhaohui, Moreno, Carlos S., Rossi, Michael R., Vertino, Paula M., Lonial, Sagar, Bernal-Mizrachi, Leon, Boise, Lawrence H.
Publicado 2016

Gain of Chromosome 1q is associated with early progression in multiple myeloma patients treated with lenalidomide, bortezomib, and dexamethasone

por Schmidt, Timothy M., Barwick, Benjamin G., Joseph, Nisha, Heffner, Leonard T., Hofmeister, Craig C., Bernal, Leon, Dhodapkar, Madhav V., Gupta, Vikas A., Jaye, David L., Wu, Jiayi, Goyal, Subir, Chen, Zhengjia, Boise, Lawrence H., Lonial, Sagar, Nooka, Ajay K., Kaufman, Jonathan L.
Publicado 2019

CD28 Regulates Metabolic Fitness for Long-Lived Plasma Cell Survival

por Utley, Adam, Chavel, Colin, Lightman, Shivana, Holling, G. Aaron, Cooper, James, Peng, Peng, Liu, Wensheng, Barwick, Benjamin G., Gavile, Catherine M., Maguire, Orla, Murray-Dupuis, Megan, Rozanski, Cheryl, Jordan, Martha S., Kambayashi, Taku, Olejniczak, Scott H., Boise, Lawrence H., Lee, Kelvin P.
Publicado 2020

Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma

por Bajpai, Richa, Sharma, Aditi, Achreja, Abhinav, Edgar, Claudia L., Wei, Changyong, Siddiqa, Arusha A., Gupta, Vikas A., Matulis, Shannon M., McBrayer, Samuel K., Mittal, Anjali, Rupji, Manali, Barwick, Benjamin G., Lonial, Sagar, Nooka, Ajay K., Boise, Lawrence H., Nagrath, Deepak, Shanmugam, Mala
Publicado 2020