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  1. 1601
    “…Strain magnitude has a controlling influence on bone adaptive response. However, questions remain as to how and if cancellous and cortical bone tissues respond differently to varied strain magnitudes, particularly at a molecular level. …”
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    Cancellous Bone May Have a Greater Adaptive Strain Threshold Than Cortical Bone
  2. 1602
    “…Reconstruction of alveolar clefts includes fistula repair and bone grafting. However, bone is often harvested from the iliac crest or the skull, which can be associated with considerable donor site morbidity, and the failure rate may be as high as 20%. …”
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    Bone Morphogenetic Protein-2 and Demineralized Bone Matrix in Difficult Bony Reconstructions in Cleft Patients
  3. 1603
    “…BACKGROUND: Glucocorticoids (GC) modulate several regulators involved in the pathogenesis of bone changes in rheumatoid arthritis (RA). Trabecular bone score (TBS) allows the indirect assessment of bone quality. …”
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    Influence of glucocorticoid treatment on trabecular bone score and bone remodeling regulators in early rheumatoid arthritis
  4. 1604
    “…BACKGROUND: One of the greatest challenges for tissue-engineered bone is the low survival rate of locally grafted cells. …”
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    Directional homing of glycosylation-modified bone marrow mesenchymal stem cells for bone defect repair
  5. 1605
    “…[Image: see text] Type 2 diabetes mellitus (T2DM) commonly affects bone quality at different hierarchical levels and leads to an increase in the risk of bone fracture. …”
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    LDN Protects Bone Property Deterioration at Different Hierarchical Levels in T2DM Mice Bone
  6. 1606
    “…BACKGROUND: The use of membrane with the guided bone regeneration (GBR) has been a controversial aspect of the implant placement, which helps achieve the primary graft stabilization and inhibit early graft loss. …”
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    Osseointegration of Dental Implants in Ridges with Insufficient Bones using Different Membranes for Guided Bone Regeneration
  7. 1607
    “…Objective: To study the bone induction and defect repair of true bone ceramics (TBC) combined with rhBMP-2 and Sr. …”
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    Bone induction and defect repair by true bone ceramics incorporated with rhBMP-2 and Sr
  8. 1608
    “…Epidemiologic studies showed that higher vitamin K (VK) consumption correlates with a reduced risk of osteoporosis, yet the dispute remains about whether VK is effective in improving bone mineral density (BMD). We sought to discover the anti-osteoporotic effect of menaquinone-4 (MK-4) and evaluate the expression of critical genes related to bone formation and bone resorption pathways in the body. …”
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    Menaquinone 4 Reduces Bone Loss in Ovariectomized Mice through Dual Regulation of Bone Remodeling
  9. 1609
    “…INTRODUCTION: Disseminated carcinomatosis of the bone marrow caused by prostate cancer is a rare condition with poor prognosis. …”
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    Disseminated carcinomatosis of the bone marrow caused by prostate cancer diagnosed with only bone marrow biopsy
  10. 1610
    “…BACKGROUND: We aimed to construct an artificial intelligence (AI) guided identification of suspicious bone metastatic lesions from the whole-body bone scintigraphy (WBS) images by convolutional neural networks (CNNs). …”
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    Automatic identification of suspicious bone metastatic lesions in bone scintigraphy using convolutional neural network
  11. 1611
    “…Major depressive disorder (MDD) is considered as a risk factor for osteoporosis. Bone mineral density (BMD), as the main tool for diagnosing osteoporosis, has been reported to have correlation with MDD in different cohorts. …”
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    Association of bone mineral density and depression in different bone sites and ages: A meta‐analysis
  12. 1612
    “…Jaw reconstruction using an additive-manufacturing titanium artificial bone (AMTAB) has recently attracted considerable attention. …”
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    Histological Evaluation of Porous Additive-Manufacturing Titanium Artificial Bone in Rat Calvarial Bone Defects
  13. 1613
    “…Many patients have comorbidities that reduce osseous healing rates, and the limited space and high weightbearing demand placed on fusion sites makes the choice of bone graft, bone graft substitute, or orthobiologic agent of utmost importance. …”
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    The Use of Bone Grafts, Bone Graft Substitutes, and Orthobiologics for Osseous Healing in Foot and Ankle Surgery
  14. 1614
    “…Calcium sulfate (CaSO(4), CS) is a synthetic bone substitute used in bone healing with biocompatible, nontoxic, bioabsorbable, osteoconductive, and good mechanical characteristics. …”
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    Preparation and Characterization of Moldable Demineralized Bone Matrix/Calcium Sulfate Composite Bone Graft Materials
  15. 1615
    “…PURPOSE: Bone metastases are common in malignant tumors, especially for the advanced cancers. …”
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    Enhancement of Cancer Chemotherapeutic Efficacy via Bone-Targeted Drug Delivery Carrier in Bone Metastases
  16. 1616
    “…In contrast, Trpv6 depletion significantly blocked the inhibitory effects of E2 on bone resorption activity, and silencing Trpv6 alleviated E2-induced osteoclast apoptosis. …”
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    TRPV6 is a potential regulator of bone resorption in bone loss induced by estrogen deficiency
  17. 1617
    por Dua, Rupak, Jones, Hugh, Noble, Philip C.
    Publicado 2021
    “…To address this problem, we have previously constructed and validated an ex-vivo bone bioreactor culture system that can maintain the viability of bone samples for an extended period ex-vivo. …”
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    Evaluation of bone formation on orthopedic implant surfaces using an ex-vivo bone bioreactor system
  18. 1618
    “…Histology and micro‐CT imaging of representative craniofacial bones (i.e., ceratohyal, frontal, dentary, and articular) of extant Antarctic fish species specifically evaluated two features that might cause the appearance of “reduced bone”: bone microstructure (e.g., bone volume fraction and structure linear density) and bone mineral density (BMD, or mass of mineral per volume of bone). …”
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    Bone microstructure and bone mineral density are not systemically different in Antarctic icefishes and related Antarctic notothenioids
  19. 1619
    “…Herein, we aimed to emulate the natural bone healing cascades by coupling the processes of angiogenesis and osteogenesis with a hybrid dual growth factor delivery system to achieve vascularized bone formation. …”
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    Spatiotemporal regulation of angiogenesis/osteogenesis emulating natural bone healing cascade for vascularized bone formation
  20. 1620
    “…We found significant increases in bone marrow adiposity and high levels of sclerostin, a negative regulator of bone formation in iGHRKO mice. …”
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    Induction of somatopause in adult mice compromises bone morphology and exacerbates bone loss during aging
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