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  1. 2221
    “…Treating critical-size bone defects beyond the body’s self-healing capacity is a challenging clinical task. …”
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    Thermosensitive hydrogel loaded with concentrated growth factors promote bone repair in segmental bone defects
  2. 2222
    “…In the physiological condition, the skeletal system’s bone resorption and formation are in dynamic balance, called bone homeostasis. …”
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    HIF-1α Regulates Bone Homeostasis and Angiogenesis, Participating in the Occurrence of Bone Metabolic Diseases
  3. 2223
    “…Backgrounds: The purpose of this study is to present our clinical experience using the Ilizarov bone transfer technique and free-flap technique in the reconstruction of large tibial bone and soft tissue defects, including an evaluation of both the management of postoperative complications and long-term outcomes. …”
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    Ilizarov Bone Transfer for Treatment of Large Tibial Bone Defects: Clinical Results and Management of Complications
  4. 2224
    “…RESULTS: the integrity of trabecular bone was damaged, the number of trabecular bone was decreased and the number of osteoclasts were increased in ARG group. …”
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    Effects of highly selective sensory/motor nerve injury on bone metabolism and bone remodeling in rats
  5. 2225
    “…Lines of evidence have shown that hypoxia-induced overproduction of ROS in bone defect region has a major impact on delaying bone regeneration. …”
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    Bone microenvironment regulative hydrogels with ROS scavenging and prolonged oxygen-generating for enhancing bone repair
  6. 2226
    “…Bone metabolism consists of bone formation and resorption and maintains a dynamic balance in vivo. …”
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    Research progress on the role and mechanism of miR-671 in bone metabolism and bone-related diseases
  7. 2227
    “…In skeletonised corpses, teeth and bones are theoretically available for age estimation, but in many cases, only single bones or even only bone fragments are available for examination. …”
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    Molecular age estimation based on posttranslational protein modifications in bone: why the type of bone matters
  8. 2228
    “…BACKGROUND: Bone is the most common site of metastasis of prostate cancer (PCa). …”
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    Procoxacin bidirectionally inhibits osteoblastic and osteoclastic activity in bone and suppresses bone metastasis of prostate cancer
  9. 2229
    “…Often, joint arthritis is accompanied by cartilage defects, joint space narrowing, osteophytes, bone sclerosis and subchondral bone cysts (SBC). …”
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    Subchondral Bone Cyst Development in Osteoarthritis: From Pathophysiology to Bone Microarchitecture Changes and Clinical Implementations
  10. 2230
    “…Autogenous bone grafting is the gold standard for replacing large bone defects. …”
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    Concentrated autologous bone marrow aspirate is not “stem cell” therapy in the repair of nonunions and bone defects
  11. 2231
    “…We also evaluated in vivo bone regeneration ability of these cells using a mouse femoral fracture model. …”
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    Bone marrow-derived dedifferentiated fat cells exhibit similar phenotype as bone marrow mesenchymal stem cells with high osteogenic differentiation and bone regeneration ability
  12. 2232
    “…Vascularized iliac crest bone flap (VIBF) and Ilizarov bone transport are effective methods to treat tibial defects with limited defect length, which most need to be explored accordingly. …”
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    Efficacy comparison of vascularized iliac crest bone flap and Ilizarov bone transport in the treatment of traumatic bone defects of the tibia combined with large soft tissue defects
  13. 2233
    “…OBJECTIVES: Fresh-frozen allograft is the gold-standard bone graft material used during revision hip arthroplasty. …”
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    Cost-effectiveness of decellularised bone allograft compared with fresh-frozen bone allograft for acetabular impaction bone grafting during a revision hip arthroplasty in the UK
  14. 2234
    “…This study aims to investigate the impact of hormonal imbalances during menopause, compounded by the natural ageing process, on bone health. Specifically, it examines the effects of increased bone turnover and focal bone balance on bone mass. …”
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    Computational Analysis of the Influence of Menopause and Ageing on Bone Mineral Density, Exploring the Impact of Bone Turnover and Focal Bone Balance—A Study on Overload and Underload Scenarios
  15. 2235
    “…BACKGROUND: The use of an interference fit wedged bone plug to provide fixation in the tibial tunnel when using bone-patellar tendon-bone autograft for anterior cruciate ligament reconstruction offers many theoretic advantages including the potential to offer a more economical and biological alternative to screw fixation. …”
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    Biomechanical testing of implant free wedge shaped bone block fixation for bone patellar tendon bone anterior cruciate ligament reconstruction in a bovine model
  16. 2236
    “…BACKGROUND: To test whether autologous transplantation of bone marrow-derived mesenchymal stem cells (BM-MSCs) expressing human bone morphogenic protein-2 (hBMP-2) can produce bone in rabbit leg muscles. …”
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    Bone formation in rabbit's leg muscle after autologous transplantation of bone marrow-derived mesenchymal stem cells expressing human bone morphogenic protein-2
  17. 2237
    “…OBJECTIVE: This study aimed to evaluate the expressions and clinical significance of bone Gla-protein (BGP), bone alkaline phosphatase (B-ALP) and C-terminal telopeptide of type I collagen (CTX) in patients with osteoporosis (OP), and to provide evidence for developing individualized treatment plans. …”
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    Expressions and clinical significance of serum bone Gla-protein, bone alkaline phosphatase and C-terminal telopeptide of type I collagen in bone metabolism of patients with osteoporosis
  18. 2238
    “…BACKGROUND: The bone scan index (BSI) using a computer-aided diagnosis system for bone scans is expected to be an objective and quantitative clinical tool for evaluating bone metastatic prostate cancer. …”
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    Prognostic value of the bone scan index using a computer-aided diagnosis system for bone scans in hormone-naive prostate cancer patients with bone metastases
  19. 2239
    por Abdullah, Walid Ahmed
    Publicado 2016
    “…AIM: To compare bone regeneration in noncritical rat calvarial bone defects filled with platelet-rich fibrin (PRF), alone or combined with beta-tricalcium phosphate (β-TCP), using micro-computed tomographic (MCT) evaluation. …”
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    Evaluation of bone regenerative capacity in rats claverial bone defect using platelet rich fibrin with and without beta tri calcium phosphate bone graft material
  20. 2240
    “…Background. Scaffolds for bone tissue engineering (BTE) can be loaded with stem and progenitor cells (SPC) from different sources to improve osteogenesis. …”
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    Bone Formation by Sheep Stem Cells in an Ectopic Mouse Model: Comparison of Adipose and Bone Marrow Derived Cells and Identification of Donor-Derived Bone by Antibody Staining
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