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  1. 3321
    “…However, the role of GDF11 in bone metabolism remains unclear. The present study was undertaken to investigate the relationship between serum GDF11 level, bone mass, and bone turnover markers in postmenopausal Chinese women. …”
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    Relationship of serum GDF11 levels with bone mineral density and bone turnover markers in postmenopausal Chinese women
  2. 3322
    “…PURPOSE: We sought to evaluate the effectiveness of bone substitutes in circumferential peri-implant defects created in the rabbit tibia. …”
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    Evaluation of bone substitutes for treatment of peri-implant bone defects: biomechanical, histological, and immunohistochemical analyses in the rabbit tibia
  3. 3323
    “…BACKGROUND: Data are scant on bone health in endocrinopathies from India. This study evaluated bone mineral density (BMD) loss in endocrinopathies [Graves’ disease (GD), type 1 diabetes mellitus (T1DM), hypogonadotrophic hypogonadism (HypoH), hypergonadotropic hypogonadism (HyperH), hypopituitarism, primary hyperparathyroidism (PHPT)] as compared to age-related BMD loss [postmenopausal osteoporosis (PMO), andropause]. …”
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    Severity and pattern of bone mineral loss in endocrine causes of osteoporosis as compared to age-related bone mineral loss
  4. 3324
    “…This study was conducted to investigate the effects of mixed bone and brisket meat on the quality characteristics and nutritional components of shank bone extract and rib extract from Hanwoo. …”
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    Effects of Mixed Bone and Brisket Meat on Physico-Chemical Characteristics of Shank Bone and Rib Extracts from Hanwoo
  5. 3325
    “…BACKGROUND: The application of bone tissue engineering for repairing bone defects has gradually shown some satisfactory progress. …”
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    Hydrogel Delivery of Mesenchymal Stem Cell–Expressing Bone Morphogenetic Protein-2 Enhances Bone Defect Repair
  6. 3326
    “…Fibroblast growth factor 2 (FGF2) plays a crucial role in bone remodeling and disease progression. However, the potential of FGF2 antagonists for treatment of patients with bone diseases has not yet been explored. …”
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    Dual Therapeutic Action of a Neutralizing Anti-FGF2 Aptamer in Bone Disease and Bone Cancer Pain
  7. 3327
    por Fujiwara, Tomohiro, Ozaki, Toshifumi
    Publicado 2016
    “…Bone sarcomas are heterogeneous malignant tumors that exhibit clinical, histological, and molecular heterogeneity. …”
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    Overcoming Therapeutic Resistance of Bone Sarcomas: Overview of the Molecular Mechanisms and Therapeutic Targets for Bone Sarcoma Stem Cells
  8. 3328
    “…Biochemical markers of bone turnover may be useful tools to quantify the degree of bone remodeling in the presence of bone metastases. …”
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    The Usefulness of Bone Biomarkers for Monitoring Treatment Disease: A Comparative Study in Osteolytic and Osteosclerotic Bone Metastasis Models
  9. 3329
    “…AIM: The aim of this study was to generate composite bone graft and investigate the rabbit fetal osteoblasts adhesion, proliferation and penetration on acellular matrices of cancellous bone. …”
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    Evaluation of tissue-engineered bone constructs using rabbit fetal osteoblasts on acellular bovine cancellous bone matrix
  10. 3330
    “…Vascularization is crucial for bone regeneration after the transplantation of tissue-engineered bone grafts in the clinical setting. …”
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    Extracellular Vesicle-functionalized Decalcified Bone Matrix Scaffolds with Enhanced Pro-angiogenic and Pro-bone Regeneration Activities
  11. 3331
    “…More insight into the biological fundamentals of leukocyte platelet-rich fibrin (L-PRF) guided healing is necessary to recommend its application, in particular in deficient bone sites that need to support implants. This study investigated the short-term bone healing effect of L-PRF treatment in cylindrical non-critical sized bone defects with 3 mm diameter and 6 mm depth in tibiae of 18 adult male New Zealand White rabbits. …”
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    The effect of L-PRF membranes on bone healing in rabbit tibiae bone defects: micro-CT and biomarker results
  12. 3332
    “…PURPOSE: This study examined real-world long-term use of guideline-recommended bone targeted agents (BTA) among patients with metastatic solid tumors. …”
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    Longitudinal patterns of bone-targeted agent use among patients with solid tumors and bone metastases in the United States
  13. 3333
    “…Here, to recapitulate such differences, we established an ex vivo bone metastasis model, termed bone-in-culture array or BICA, by fragmenting mouse bones preloaded with breast cancer cells via intra-iliac artery injection. …”
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    Bone-in-culture array as a platform to model early-stage bone metastases and discover anti-metastasis therapies
  14. 3334
    “…BACKGROUND: Bone and soft-tissue defects in infected wound have been an intractable problem to many surgical consultations. …”
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    Combined negative pressure wound therapy with open bone graft for infected wounds with bone defects: An experimental study
  15. 3335
    “…The assessment of bone damage is required to evaluate disease severity and treatment efficacy both in arthritis patients and in experimental arthritis models. …”
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    Automated Quantification of Early Bone Alterations and Pathological Bone Turnover in Experimental Arthritis by in vivo PET/CT Imaging
  16. 3336
    “…Aging and obesity induce ectopic adipocyte accumulation in bone marrow cavities. This process is thought to impair osteogenic and hematopoietic regeneration. …”
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    Adipocyte Accumulation in the Bone Marrow during Obesity and Aging Impairs Stem Cell-Based Hematopoietic and Bone Regeneration
  17. 3337
    “…In this context, a 3D anatomical and perfusion MR imaging protocol was developed to follow the evolution of bone regeneration and the neo-vascularization in femoral bone defects in rats. …”
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    3D anatomical and perfusion MRI for longitudinal evaluation of biomaterials for bone regeneration of femoral bone defect in rats
  18. 3338
    “…Abnormalities of bone turnover are commonly observed in patients with chronic kidney disease (CKD), and the low‐turnover bone disease is considered to be associated with low serum parathyroid hormone (PTH) levels and skeletal resistance to PTH. …”
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    Indoxyl sulfate, a uremic toxin in chronic kidney disease, suppresses both bone formation and bone resorption
  19. 3339
    “…Although bone morphogenetic protein-2 (BMP2) has demonstrated extraordinary potential in bone formation, its clinical applications require supraphysiological milligram-level doses that increase postoperative inflammation and inappropriate adipogenesis, resulting in well-documented life-threatening cervical swelling and cyst-like bone formation. …”
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    Small molecule-mediated tribbles homolog 3 promotes bone formation induced by bone morphogenetic protein-2
  20. 3340
    “…Bone mineral density was measured using dual-energy X-ray absorptiometry. …”
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    The Relationship of Disordered Eating Attitudes with Stress Level, Bone Turnover Markers, and Bone Mineral Density in Obese Adolescents
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