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3801“…Icariin, a typical flavonol glycoside, is the main active component of Herba Epimedii, which was used to cure bone-related diseases in China for centuries. It has been reported that Icariin can be delivered locally by biomaterials and it has an osteogenic potential for bone tissue engineering. …”
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3802por Sayilekshmy, Manasi, Hansen, Rie Bager, Delaissé, Jean-Marie, Rolighed, Lars, Andersen, Thomas Levin, Heegaard, Anne-Marie“…Mounting evidence from animal studies suggests a role of the nervous system in bone physiology. However, little is known about the nerve fiber localization to human bone compartments and bone surface events. …”
Publicado 2019
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3803por Wendler, Sebastian, Schlundt, Claudia, Bucher, Christian H., Birkigt, Jan, Schipp, Christian J., Volk, Hans-Dieter, Duda, Georg N., Schmidt-Bleek, Katharina“…Within an aging population, fracture incidences will rise and with the augmented risks of impaired healing the overall risk of delayed bone regeneration will substantially increase in elderly patients. …”
Publicado 2019
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3804por Song, Lu, Tan, Jingyi, Wang, Zhongxiu, Ding, Peihui, Tang, Qi, Xia, Mengjiao, Wei, Yingming, Chen, Lili“…Interleukin 17A (IL-17A) exerts pleiotropic effects on periodontitis, partially through enhancement of alveolar bone loss. Osteoclasts are the main culprits that absorb alveolar bone. …”
Publicado 2019
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3805“…In the present study, we aimed to compare the bone regenerative effect of exosomes secreted by bone marrow mesenchymal stem cells (BMSCs) derived from type 1 diabetes rats (dBMSC‐exos) and exosomes secreted by BMSCs derived from normal rats (nBMSC‐exos). …”
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3806por Garg, Abhilasha, Aggarwal, Anshita, Pal, Rimesh, Dhaliwal, Ruban, Singh, Priyanka, SACHDEVA, NARESH, Bhansali, Anil, bhadada, SanjayMaterias: “…Bone and Mineral Metabolism…”
Publicado 2019
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3807por Misof, Barbara M., Blouin, Stéphane, Roschger, Paul, Werzowa, Johannes, Klaushofer, Klaus, Lehmann, Gabriele“…OBJECTIVES: Little is known about bone mineralization and osteocyte lacunae properties in chronic kidney disease mineral bone disorder (CKD-MBD). …”
Publicado 2019
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3808“…INTRODUCTION: Osteoporosis (OP) is a common polygenic disorder in the aging population, and several single nucleotide polymorphisms (SNPs) in the alpha-L-iduronidase (IDUA) gene and patched homolog 1 (PTCH1) gene regulate bone metabolism and affect bone mass. The study aimed at investigating the relationships of rs3755955 and rs6831280 in the IDUA gene and rs28377268 in the PTCH1 gene with bone mineral density (BMD), bone turnover markers (BTMs), and fractures in the elderly Chinese subjects with OP. …”
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3809por Paton‐Hough, Julia, Tazzyman, Simon, Evans, Holly, Lath, Darren, Down, Jenny M, Green, Alanna C, Snowden, John A, Chantry, Andrew D, Lawson, Michelle A“…Multiple myeloma is a plasma cell malignancy, which develops in the bone marrow and frequently leads to severe bone destruction. …”
Publicado 2018
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3810“…Microdamage is a component of bone quality believed to play an integral role in bone health. …”
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3811“…Clinicians should be alert to the presence of slight brightness and osteosclerotic changes of bones on plain X‐rays, especially in patients without a history of gastric, colon, breast, lung, or prostate cancers, which could lead to the diagnosis of disseminated carcinomatosis of bone marrow.…”
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3813por Arnautovic-Halimic, Ajla, Begic, Amela, Agic-Bilalagic, Selma, Basic, Amila, Hadzimuratovic, Amila, Ahmed-Jesenkovic, Dzan“…INTRODUCTION: Osteoporosis is a consequence of reduction in bone mass and disorders of bone structure, which makes the bones prone to fractures. …”
Publicado 2019
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3814por Coelho, Fernanda, Cavicchioli, Maurício, Specian, Sybele Saska, Scarel-Caminaga, Raquel Mantuaneli, Penteado, Letícia de Aquino, de Medeiros, Alexandra Ivo, Ribeiro, Sidney José de Lima, Capote, Ticiana Sidorenko de Oliveira“…Bone tissue engineering seeks to adequately restore functions related to physical and biological properties, aiming at a repair process similar to natural bone. …”
Publicado 2019
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3815por Movérare-Skrtic, Sofia, Nilsson, Karin H., Henning, Petra, Funck-Brentano, Thomas, Nethander, Maria, Rivadeneira, Fernando, Coletto Nunes, Glaucia, Koskela, Antti, Tuukkanen, Juha, Tuckermann, Jan, Perret, Christine, Souza, Pedro Paulo Chaves, Lerner, Ulf H., Ohlsson, Claes“…Osteoblast-derived NOTUM reduces cortical bone mass in mice and the NOTUM locus is associated with bone mineral density in humans.…”
Publicado 2019
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3816por Kahle, Patricia, Rolvien, Tim, Kierdorf, Horst, Roos, Anna, Siebert, Ursula, Kierdorf, Uwe“…Negative correlations with age existed for trabecular number and thickness as well as for trabecular bone volume fraction in the juveniles. The findings suggest a reduction in trabecular bone volume fraction with age, due to the bone trabeculae becoming thinner, less numerous and more widely spaced. …”
Publicado 2019
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3817“…Growth factors in serum-free conditioned media from human bone marrow-derived mesenchymal stem cells (MSC-CM) are known to be effective in bone regeneration. …”
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3818por Dai, Jinlu, Escara-Wilke, June, Keller, Jill M., Jung, Younghun, Taichman, Russell S., Pienta, Kenneth J., Keller, Evan T.“…Prostate cancer (PCa) metastasizes selectively to bone through unknown mechanisms. In the current study, we identified exosome-mediated transfer of pyruvate kinase M2 (PKM2) from PCa cells into bone marrow stromal cells (BMSCs) as a novel mechanism through which primary tumor-derived exosomes promote premetastatic niche formation. …”
Publicado 2019
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3819por Liu, Yiping, Sun, Xiaolin, Yu, Jize, Wang, Jia, Zhai, Peisong, Chen, Siyu, Liu, Manxuan, Zhou, Yanmin“…It has been considered to be effective in bone regeneration and is mainly used for oral and maxillofacial bone. …”
Publicado 2019
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3820por Perale, Giuseppe, Monjo, Marta, Ramis, Joana M., Øvrebø, Øystein, Betge, Felice, Lyngstadaas, Petter, Haugen, Håvard J.“…Consequently, bone is the second most transplanted tissue just after blood. …”
Publicado 2019
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