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149001por Pei, Chong Zhe, Liu, Bo, Li, Ye Ting, Fang, Lu, Zhang, Yi, Li, Yi Gang, Meng, Shu“…The aims of the present study were to examine (1) in vitro the effects of miR-126 on the homing and stemness of late outgrowth EPCs (LOCs), along with relevant signaling pathways, and (2) in vivo the effects of modulating LOCs by manipulating miR-126 expression on LOC homing and reendothelialization of injured arteries in GK rats (a non-obese diabetes model). METHODS: Rat bone marrow-derived LOCs were transfected with miR-126 inhibitor or lentiviral vectors expressing miR-126. …”
Publicado 2020
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149002“…BACKGROUND: Osteosarcoma (OS) is the most common malignant primary bone tumor occurring in children and young adults, which occupies the second important cause of tumor-associated deaths among children and young adults. …”
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149003por Jiang, Yiwen, Xiao, Lianbo, Fu, Wenwei, Tang, Yuexun, Lertnimitphun, Peeraphong, Kim, Nami, Zheng, Changwu, Tan, Hongsheng, Lu, Yue, Xu, Hongxi“…GH inhibited nitric oxide (NO) production, inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression, cytokine interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) production, and messenger RNA (mRNA) expression to attenuate inflammatory responses in lipopolysaccharide (LPS)-induced RAW 264.7 cells or stimulated bone marrow-derived macrophages (BMDMs). GH inhibited nuclear factor-κB (NF-κB) and mitogen-activated protein kinase (MAPK) pathways, the nuclear translocation of transcription factors NF-κB and activator protein 1 (AP-1), as well as upstream signaling of the toll-like receptor 4 (TLR4)-myeloid differentiation primary response 88 (MyD88) pathway in stimulated macrophages. …”
Publicado 2020
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149004“…METHODS: We used semi-quantitative reverse-transcriptase PCR (RT-PCR) and Western blot to investigate the expression of full length p53 (TAp53), Delta40p53, Delta133p53 or p53beta in diagnostic marrow from a clinical cohort of 50 BCP-ALL patients without TP53 mutation (29 males and 21 females, age range 2–14 years) and in the bone marrow cells of 4 healthy donors (used as controls). …”
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149005“…Flow cytometry was used to evaluate in vitro bone marrow derived dendritic cell (BM-DC) maturation and T cell proliferation induced by B. subtilis-Cap. …”
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149006por Espinosa, José, Ferreras, M. Carmen, Benavides, Julio, Cuesta, Nerea, Pérez, Claudia, García Iglesias, M. José, García Marín, J. Francisco, Pérez, Valentín“…They were grouped into parasitic conditions (n= 65; 24.34%) represented by encephalitozoonosis, hepatic coccidiosis, hepatoperitoneal cysticercosis, intestinal coccidiosis, parasitic gastritis and cutaneous ectoparasitosis; bacterial diseases (n = 56; 20.97%) including pseudotuberculosis, blue breast, skin abscesses, tularemia, pneumonic pasteurellosis and staphylococcal infections; nutritional and metabolic diseases (n = 48; 17.97%) with epizootic rabbit enteropathy, hepatic steatosis and pregnancy toxemia as prominent diseases; viral infections (n= 31; 11.61%) comprising rabbit hemorrhagic disease and myxomatosis and miscellaneous causes (n = 31; 11.61%) where rabbit enteritis complex, renal conditions (nephrosis), heat stroke, and arterial bone metaplasia were included; neoplasms (n = 12; 4.49%) represented by uterine adenocarcinoma, mammary adenocarcinoma, cutaneous fibroma, intestinal lymphoma and hepatic cholangiocarcinoma; toxicoses (n = 11; 4.11%); trauma-related injuries (n = 9; 3.37%) and finally congenital diseases (n = 4; 1.49%). …”
Publicado 2020
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149007por Williams, Kevin, Askew, Christian, Mazoue, Christopher, Guy, Jeffrey, Torres-McGehee, Toni M, Jackson III, J Benjamin“…INTRODUCTION: Vitamin D is paramount to bone health and little is known about vitamin D’s role in the prevention of stress fractures in high-risk athletes. …”
Publicado 2020
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149008por Escamilla Gómez, Virginia, García-Gutiérrez, Valentín, López Corral, Lucía, García Cadenas, Irene, Pérez Martínez, Ariadna, Márquez Malaver, Francisco J., Caballero-Velázquez, Teresa, González Sierra, Pedro A., Viguria Alegría, María C., Parra Salinas, Ingrid M., Calderón Cabrera, Cristina, González Vicent, Marta, Rodríguez Torres, Nancy, Parody Porras, Rocío, Ferra Coll, Christelle, Orti, Guillermo, Valcárcel Ferreiras, David, De la Cámara LLanzá, Rafael, Molés, Paula, Velázquez-Kennedy, Kyra, João Mende, María, Caballero Barrigón, Dolores, Pérez, Estefanía, Martino Bofarull, Rodrigo, Saavedra Gerosa, Silvanna, Sierra, Jorge, Poch, Marc, Zudaire Ripa, María T., Díaz Pérez, Miguel A., Molina Angulo, Blanca, Sánchez Ortega, Isabel, Sanz Caballer, Jaime, Montoro Gómez, Juan, Espigado Tocino, Ildefonso, Pérez-Simón, José AEnlace del recurso
Publicado 2019
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149009por Rapoport, Alison B, Fine, Danielle, Manne-Goehler, Jennifer, Herzig, Shoshana J, Rowley, Christopher F“…Sentinel admission infection types were 1) skin and soft tissue (SSTI) N = 111 (42%), 2) endocarditis N = 70 (30%), 3) bone and joint N = 26 (10%), 4) pyogenic spinal N = 39 (15%), 5) isolated bacteremia N = 9 (3%) 6) and acute viral hepatitis N = 8 (3%). …”
Publicado 2017
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149010por Snowden, John A., Saccardi, Riccardo, Orchard, Kim, Ljungman, Per, Duarte, Rafael F., Labopin, Myriam, McGrath, Eoin, Brook, Nigel, de Elvira, Carmen Ruiz, Gordon, Debra, Poirel, Hélène A., Ayuk, Francis, Beguin, Yves, Bonifazi, Francesca, Gratwohl, Alois, Milpied, Noel, Moore, John, Passweg, Jakob, Rizzo, J. Douglas, Spellman, Stephen R., Sierra, Jorge, Solano, Carlos, Sanchez-Guijo, Fermin, Worel, Nina, Gusi, Andreu, Adams, Gillian, Balan, Theodor, Baldomero, Helen, Macq, Gilles, Marry, Evelyne, Mesnil, Florence, Oldani, Elena, Pearce, Rachel, Perry, Julia, Raus, Nicole, Schanz, Urs, Tran, Steven, Wilcox, Leonie, Basak, Grzegorz W., Chabannon, Christian, Corbacioglu, Selim, Dolstra, Harry, Kuball, Jürgen, Mohty, Mohamad, Lankester, Arjan, Montoto, Sylvia, Nagler, Arnon, Styczynski, Jan, Yakoub-Agha, Ibrahim, de Latour, Regis Peffault, Kroeger, Nicolaus, Brand, Ronald, de Wreede, Liesbeth C., van Zwet, Erik, Putter, HeinEnlace del recurso
Publicado 2019
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149011por Wang, Xiao-Jian, Xu, Xi-Qi, Sun, Kai, Liu, Ke-Qiang, Li, Su-Qi, Jiang, Xin, Zhao, Qin-Hua, Wang, Lan, Peng, Fu-Hua, Ye, Jue, Wu, Yan, Jiang, Rui, Zhang, Jin, Huang, Wei, Wei, Wen-Bin, Yan, Yi, Li, Jing-Hui, Liu, Qian-Qian, Li, Sheng, Wang, Yong, Zhang, Shu-Yang, Zhang, Xue, Jing, Zhi-Cheng“…IMPORTANCE: Idiopathic pulmonary arterial hypertension (IPAH) is a fatal disease with high heritability; however, the bone morphogenetic protein receptor 2 (BMPR2) gene only accounts for 17% of IPAH. …”
Publicado 2020
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149012Publicado 2020“…Head magnetic resonance imaging (MRI) usage increased from 1.0% to 15.0% (P < 0.001). The bone scan increased from 35.0% to 78.0% (P < 0.001). …”
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149013“…Gross pathology and micropathology of sternal bone marrow, spleen, mesenteric and retropharyngeal lymph nodes, thymus, liver and kidney were completed. …”
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149014por Nadin, Tom, Wallis, Dinny, Holroyd, Christopher R., D’Angelo, Stefania, Walker-Bone, Karen, Edwards, Christopher J.Enlace del recurso
Publicado 2020
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149015por Tong, Xin, Chaudhry, Zunaira, Lee, Chih-Chun, Bone, Robert N., Kanojia, Sukrati, Maddatu, Judith, Sohn, Paul, Weaver, Staci A., Robertson, Morgan A., Petrache, Irina, Evans-Molina, Carmella, Kono, TatsuyoshiEnlace del recurso
Publicado 2020
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149016por Isgren, C. M., Salem, S. E., Singer, E. R., Wylie, C. E., Lipreri, G., Graham, R. J. T. Y., Bladon, B., Boswell, J. C., Fiske‐Jackson, A. R., Mair, T. S., Rubio‐Martínez, L. M.“…Increased mortality was associated with bone fracture/osteomyelitis (HR 2.43, 95% CI 1.12–5.26, P = 0.03), tendon involvement (≥30% cross sectional area) (HR 3.78 95% CI 1.78–8.04, P = 0.001), duration of general anaesthesia (HR 1.01, 95% CI 1.00–1.02, P = 0.04), post‐operative synoviocentesis (HR 3.18, 95% CI 1.36–7.43, P = 0.006) and post‐operative wound dehiscence (HR 2.5, 95% CI 1.08–5.65, P = 0.04). …”
Publicado 2019
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149017por Dermitzaki, Eleni, Manolakos, Emmanouil, Kleanthous, Kleanthis, Mastorakos, George, Papadimitriou, Dimitrios T“…His linear growth presented an acceleration the last 2 years from +0.85 to +1.81 SD and his bone age was advanced by 2 years with a statural height at -0.5 SD, not in accordance with the mean parental height (+0.90 SD). …”
Publicado 2020
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149018por Kim, Jihyun, Kim, Su Jin, Lee, Jieun, Lee, Young Ah, Shin, Choong Ho, Seo, Ji Young“…The mean age of IGHD was 6.02, and the mean bone age was 4.49 years. OGHD was 7.38, 5.74, TS was 7.13, 6.52, and SGA was 5.61, 4.96 years. …”
Publicado 2020
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149019por Dermitzaki, Eleni, Manolakos, Emmanouil, Tagalakis, Panagiotis, Kleanthous, Kleanthis, Papadimitriou, Dimitrios T“…Her height was 2,5 SD lower than the mean parental height curve, and her bone age was delayed only by 3 months. She already had a normal (46XX) peripheral blood karyotype (70 mitoses). …”
Publicado 2020
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149020“…Biopsies of tongue and bone marrow also showed amyloidosis thereby securing the diagnosis of systemic amyloidosis, and chemotherapy was initiated. …”
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