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149761por Banda, Amina, Privé, Bastiaan M., Allach, Youssra, Uijen, Maike J. M., Peters, Steffie M. B., Loeff, Cato C., Gotthardt, Martin, Muselaers, Constantijn H. J., Witjes, J. Alfred, van Oort, Inge M., Sedelaar, J. P. Michiel, Westdorp, Harm, Mehra, Niven, Khreish, Fadi, Ezziddin, Samer, Sabet, Amir, Kreissl, Michael C., Winkens, Thomas, Seifert, Philipp, Janssen, Marcel J. R., van Gemert, Willemijn A. M., Nagarajah, James“…One patient that received (225)Ac-PSMA developed grade 3–4 bone marrow toxicity. The median PFS was 12 months (95% confidence interval (CI), 4.09–19.9 months). …”
Publicado 2022
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149762por Fujiwara, Yusuke, Ding, Chenyang, Sanada, Yohei, Yimiti, Dilimulati, Ishikawa, Masakazu, Nakasa, Tomoyuki, Kamei, Naosuke, Imaizumi, Kazunori, Lotz, Martin K., Akimoto, Takayuki, Miyaki, Shigeru, Adachi, Nobuo“…Skeletal development of Cart- and Glob-miR-23clus KO mice was grossly normal although Glob-miR-23clus KO had reduced body weight, adipose tissue and bone density. In the aging model and surgically-induced OA model, Cart- and Glob-miR-23clus KO mice exhibited mild OA-like changes such as proteoglycan loss and cartilage fibrillation. …”
Publicado 2023
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149763por Feng, Zhi-wei, Tang, Yu-chen, Sheng, Xiao-yun, Wang, Sheng-hong, Wang, Yao-bin, Liu, Zhong-cheng, Liu, Jin-min, Geng, Bin, Xia, Ya-yi“…The basic pathological manifestations are synovial inflammation, pannus formation, and erosion of articular cartilage, bone destruction will eventually lead to joint deformities and loss of function. …”
Publicado 2023
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149764por Yiğit, Şeyhmus, Aslan, Rıdvan, Arslan, Hüseyin, Özkul, Emin, Atic, Ramazan, Akar, Mehmet Sait“…Height/weight values greater than the 90 percentile, varus or valgus angulation greater than 25.5°, bone apposition values greater than 9.5mm, medial translation values greater than 11mm, and older than eight years patients type IV fractures were more common in such patients. …”
Publicado 2022
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149765por Resch, Sandra, Takayama Fouladgar, Sarah, Zacherl, Mathias, Sheikh, Gabriel T., Liubchenko, Grigory, Rumiantcev, Mikhail, Unterrainer, Lena M., Wenter, Vera, Bartenstein, Peter, Ziegler, Sibylle I., Ilhan, Harun, Beyer, Leonie, Böning, Guido, Delker, AstridEnlace del recurso
Publicado 2023
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149766por Gong, Matthew F., Li, William T., Bhogal, Sumail, Royes, Brittany, Heim, Tanya, Silvaggio, Maria, Malek, Marcus, Dhupar, Rajeev, Lee, Stella J., McGough, Richard L., Weiss, Kurt R.“…Three subjects were excluded for having bone sarcomas, and five subjects were excluded due to final pathology, which was ultimately inconsistent with sarcoma. …”
Publicado 2023
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149767por Chen, Huanhuan, Yang, Keqing, Pang, Lingxiao, Fei, Jing, Zhu, Yongliang, Zhou, Jianwei“…Mouse PMN-MDSCs were obtained from bone marrow (BM)-derived CD11b(+)Ly6G(+)Ly6C(low) cells sorted by fluorescence-activated cell sorting with treatment of GM-CSF and IL-6, and the immunosuppressive activity of PMN-MDSCs was evaluated by flow cytometry (FCM) and ELISA. …”
Publicado 2023
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149768por Zhao, Jinbo, Pan, Hongbin, Zhao, Wenjiang, Li, Wei, Li, Haojie, Tian, Zhongxiao, Meng, Dayong, Teng, Yuting, Li, Xinlu, He, Yang, Shi, Hongmei, Ge, Changrong, Wang, Kun“…Here, one hundred and fifty Chahua No. 2 laying hens (the CH2 group, which has precocious puberty) and one hundred and fifty Wu Liang Shan black-bone laying hens (the WLS group, a late-maturing chicken breed) with similar weights and ages were randomly selected. …”
Publicado 2023
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149769por Li, Gloria Hoi-Yee, Cheung, Ching-Lung, Tan, Kathryn Choon-Beng, Kung, Annie Wai-Chee, Kwok, Timothy Chi-Yui, Lau, Wallis Cheuk-Yin, Wong, Janus Siu-Him, Hsu, Warrington W.Q., Fang, Christian, Wong, Ian Chi-Kei“…Due to limited availability of dual-energy X-ray absorptiometry (DXA), hip fracture prediction models without using bone mineral density (BMD) data are essential. We aimed to develop and validate 10-year sex-specific hip fracture prediction models using electronic health records (EHR) without BMD. …”
Publicado 2023
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149770“…In pretreatment prognostic analysis, age, T stage, N stage, M stage, bone metastasis, liver metastasis, and brain metastasis were found to be associated with the survival of both LCNEC and SCLC, besides sex, bilaterality, and lung metastasis were additional prognostic factors for SCLC. …”
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149771por Wohlgemut, Jared M., Marsden, Max E. R., Stoner, Rebecca S., Pisirir, Erhan, Kyrimi, Evangelia, Grier, Gareth, Christian, Michael, Hurst, Thomas, Marsh, William, Tai, Nigel R. M., Perkins, Zane B.“…Overall, clinical examination had a moderate ability to detect LLTIs, which varied by body region: head (sensitivity 69.7%, positive predictive value (PPV) 59.1%), chest (sensitivity 58.7%, PPV 53.3%), abdomen (sensitivity 51.9%, PPV 30.7%), pelvis (sensitivity 23.5%, PPV 50.0%), and long bone fracture (sensitivity 69.9%, PPV 74.3%). Clinical examination poorly detected life-threatening thoracic (sensitivity 48.1%, PPV 13.0%) and abdominal (sensitivity 43.6%, PPV 20.0%) bleeding. …”
Publicado 2023
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149772por Yu, Yong-Lin, Wu, Jun-Jie, Lin, Chuan-Chuan, Qin, Xian, Tay, Franklin R., Miao, Li, Tao, Bai-Long, Jiao, Yang“…Fluorescence staining, assays for alkaline phosphatase activity, collagen secretion and extracellular matrix mineralization, quantitative real‑time reverse transcription‑polymerase chain reaction, and enzyme-linked immunosorbent assay (ELISA) were used to evaluate the inflammatory response and osteogenic ability in bone marrow stromal cells (MSCs), RAW264.7 cells and their co-culture system. …”
Publicado 2023
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149773por Palmisano, Anna, Gnasso, Chiara, Cereda, Alberto, Vignale, Davide, Leone, Riccardo, Nicoletti, Valeria, Barbieri, Simone, Toselli, Marco, Giannini, Francesco, Loffi, Marco, Patelli, Gianluigi, Monello, Alberto, Iannopollo, Gianmarco, Ippolito, Davide, Mancini, Elisabetta Maria, Pontone, Gianluca, Vignali, Luigi, Scarnecchia, Elisa, Iannaccone, Mario, Baffoni, Lucio, Spernadio, Massimiliano, de Carlini, Caterina Chiara, Sironi, Sandro, Rapezzi, Claudio, Esposito, Antonio“…Chest CT was analysed in a single core lab and behind pneumonia CT scores were extracted opportunistic data about atherosclerotic profile (calcium score according to Agatston method), liver steatosis (≤ 40 HU), myosteatosis (paraspinal muscle F < 31.3 HU, M < 37.5 HU), and osteoporosis (D12 bone attenuation < 134 HU). Differences according to treatment and outcome were assessed with ANOVA. …”
Publicado 2023
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149774por Suo, Xiaohui, Zheng, Fang, Wang, Dongmei, Zhao, Liyun, Liu, Jie, Li, Ling, Zhang, Zhihua, Zhang, Congcong, Li, Yinling, Yang, Sisi, Zhao, Xuemei, Shi, Rui, Wu, Yan, Jiao, Zongjiu, Song, Jiaojie, Zhang, Ling, Lu, Xinxiao, Yuan, Linyu, Gao, Sifeng, Zhang, Jilei, Zhao, Xingli, Bai, Guanchen, Liu, Kaiqi, Mi, Yingchang“…Secondary endpoints included measurable residual disease (MRD) of bone marrow assessed by flow cytometry, overall survival (OS), event-free survival (EFS), disease-free survival (DFS), and the safety of regimens. …”
Publicado 2023
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149775por Kandasamy, Karthikeyan, Johana, Nuryanti Binti, Tan, Lay Geok, Tan, Yvonne, Yeo, Julie Su Li, Yusof, Nur Nazneen Binte, Li, Zhihui, Koh, Jiayu, Ginhoux, Florent, Chan, Jerry K. Y., Choolani, Mahesh, Mattar, Citra N. Z.“…IUT was performed at E14 following maternal DT administration 24 h prior. Bone marrow-derived mononuclear cells were transplanted, obtained from semi-allogenic BALB/c (paternal-derived; pIUT), C57BL/6 (maternal-derived; mIUT), or fully allogenic (aIUT) C3H donor mice. …”
Publicado 2023
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149776por Chang, Wenjing, Zhu, Jichao, Yang, Dianyu, Shang, Anquan, Sun, Zujun, Quan, Wenqiang, Li, Dong“…RESULTS: Plasma versican and plasma exosomal versican expression in NSCLC patients was significantly upregulated and was significantly higher in T3 + T4 patients compared with T1 + T2 patients (P < 0.05); the levels of plasma versican and plasma exosomal versican were positively correlated with lymph node metastasis, distant metastases (e.g., brain, bone), and mutation(e.g., EGFR,ALK)in NSCLC patients (all P < 0.05). …”
Publicado 2023
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149777por Randon, Giovanni, Aoki, Yu, Cohen, Romain, Provenzano, Leonardo, Nasca, Vincenzo, Klempner, Samuel J, Maron, Steven B, Cerantola, Riccardo, Chao, Joseph, Fornaro, Lorenzo, Ferrari Bravo, Walter, Ghelardi, Filippo, Ambrosini, Margherita, Manca, Paolo, Salati, Massimiliano, Kawazoe, Akihito, Zhu, Valerie, Cowzer, Darren, Genovesi, Virginia, Lonardi, Sara, Shitara, Kohei, André, Thierry, Pietrantonio, Filippo“…In the multivariable models, Eastern Cooperative Oncology Group Performance Status of 1 or 2, non-resected primary tumor, presence of bone metastases and malignant ascites were independently associated with poorer PFS and OS. …”
Publicado 2023
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149778por Jess, Jennifer, Yates, Bonnie, Dulau-Florea, Alina, Parker, Kevin, Inglefield, Jon, Lichtenstein, Dan, Schischlik, Fiorella, Ongkeko, Martin, Wang, Yanyu, Shahani, Shilpa, Cullinane, Ann, Smith, Hannah, Kane, Eli, Little, Lauren, Chen, Dong, Fry, Terry J, Shalabi, Haneen, Wang, Hao-Wei, Satpathy, Ansuman, Lozier, Jay, Shah, Nirali N“…Additional analyses included correlation of hematologic toxicities with neurotoxicity and exploring effects of hemophagocytic lymphohistiocytosis-like toxicities (HLH) on bone marrow recovery and cytopenias. Coagulopathy was defined as evidence of bleeding or abnormal coagulation parameters. …”
Publicado 2023
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149779por O’Neill, Dan G., Edmunds, Grace L., Urquhart-Gilmore, Jade, Church, David B., Rutherford, Lynda, Smalley, Matthew J., Brodbelt, Dave C.“…BACKGROUND: Osteosarcoma is a malignant bone neoplasia that has high welfare consequences for affected dogs. …”
Publicado 2023
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149780por Yuan, Feifei, Peng, Wei, Yang, Yuying, Xu, Jiaqi, Liu, Yudong, Xie, Yong, Huang, Tingmo, Shi, Chaoran, Ding, Yinghe, Li, Chengjun, Qin, Tian, Xie, Shanshan, Zhu, Fengzhang, Lu, Hongbin, Huang, Jianjun, Hu, Jianzhong“…METHODS: We extracted the macrophages and EPC from the bone marrow suspension of C57BL/L mice by centrifugation. …”
Publicado 2023
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