“…Conditions with largest HRQoL improvement over time were anxiety/depression, ADHD, autism, bone/joint/muscle problem, recurrent abdominal pain, recurrent pain in other part, frequent headache, diarrhea and day-wetting. …”
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“…FAPI-positive local recurrence showed the highest uptake intensity, followed by lymphatic, other site-associated (bone and pleura), and pulmonary lesions (mean SUV(max), 4.7 versus 3.7 versus 3.0 versus 2.2, respectively; P < 0.0001). …”
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“…Fibrocytes (CD45(+)collagen-1(+)) were detected in the bone marrow (BM), blood and fibrotic lesions by flow cytometry and confocal microscopy, respectively. …”
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“…The cells of peripheral blood, spleen and bone marrow from 5xFAD mice were treated with Pg to detect the proportional and functional alterations of mMDSCs in vitro. …”
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“…BACKGROUND: Postmenopausal osteoporosis (PMOP) is a common bone disorder. Existing study has confirmed the role of exosome in regulating RNA N6-methyladenosine (m6A) methylation as therapies in osteoporosis. …”
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“…METHODS: For retrospective analysis, 80 patients with malignant OS diagnosed and treated in our hospital from June 2016 to June 2017 were selected as the observation group, and 80 patients with benign bone tumors during the same period were selected as the control group. …”
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“…INTRODUCTION: Chronic kidney disease-mineral and bone disorder (CKD-MBD) is frequently observed in maintenance hemodialysis (MHD) patients and is associated with fracture, muscle weakness, malnutrition, etc.; however, relationships of CKD-MBD markers and fatigue are not well established. …”
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“…Four out of five ICT patients exhibited rather high [(89)Zr]Zr-Df-IAB22M2C uptake in the bone marrow. Two of these four patients as well as two other patients yielded pronounced [(89)Zr]Zr-Df-IAB22M2C uptake within nonmetastatic lymph nodes. …”
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“…Similar biodistribution profiles were observed for both radiopeptides, however, higher uptake was noticed in the kidneys, liver and bone for [(225)Ac]Ac-DOTA-JR11 than [(177)Lu]Lu-DOTA-JR11. …”
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“…Rapid urinary excretion and low liver and bone uptake were seen for (134)Ce/(225)Ac-DOTA/MACROPA. …”
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“…Through hormonal changes and the changing physiological state, women are at greater risk of anaemia, bone weakness and osteoporosis. The aim of the study was to assess changes in the dietary pattern among women from the Silesian Agglomeration in Poland between 2011 and 2022. …”
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“…Distant metastases were documented in 1.1%, involving lungs 44%, bone 40%, liver 12%, and brain 4%. The most common treatment modality was surgery alone: 63.6% followed by surgery and adjuvant radiation: 33%. …”
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“…Tumors of the parathyroid glands, when associated with PTH (parathyroid hormone) excess, display a large area of complications; in addition to the classical clinical picture of primary hyperparathyroidism (PHP), a complex panel of other symptoms/signs can be identified, including memory and cognitive impairment, chronic asthenia/fatigue, reduced muscle functionality, depressive mood, non-specific bone pain, and loss of sleep quality. The perception of quality of life (QoL) can be supplementarily enhanced by their progressive onset, which makes many patients not be fully aware of them. …”
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“…All patients showed global TS inhibition reflected in plasma dUrd levels (p < 0.001) and (18)F-FLT flares of TS-responsive normal tissues including small bowel and bone marrow (p = 0.004 each). Notably, 83% (5/6) of patients who exhibited (18)F-FLT flares were also RECIST responders with a median OS of 31 m, unlike patients who did not exhibit (18)F-FLT flares (15 m). …”
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“…Cluster 2 included 37 subjects and was marked by younger patients (29.7 ± 6.1 years, p=.038) with a more pro-inflammatory synovial fluid biomarker profile, higher ACLOAS Hoffa’s synovitis score (p=.001), and a higher incidence of subchondral bone fractures (54%, p=.002). There were no differences between clusters in time from injury to surgery (p=), BMI (p=.141), or ACLOAS meniscus (p=.086), cartilage (p=.730), or effusion scores (p=.202) CONCLUSIONS: Given the variable outcomes seen following ACL reconstruction (ACLR) surgery, a better understanding of the pathophysiology following ACL injury is needed. …”
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“…A majority of members report routine use of synovial rasping/trephination (86.0%) and notch microfracture (66.5%), while a minority report use of more involved biologic supplementations including classic fibrin clot (4.9%), platelet-rich plasma (8.9%), and bone marrow aspirate concentrate (2.9%). Timing of return to weight-bearing and range of motion appear to depend on hoop stress integrity; tears with intact hoop integrity were, on average, permitted to return to weight bearing more quickly (1.4 weeks for partial weight bearing, 3.6 weeks for full weight bearing), versus tears that demonstrated loss of hoop integrity (3.9 weeks for partial weight bearing, 6.2 weeks for full weight bearing). …”
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“…The game came to fruition after following an iterative process model with several prototypes. Game developers and bone marrow transplant nurses were recruited to perform an expert usability evaluation of the Walking Warrior prototype by completing a heuristic questionnaire and providing qualitative suggestions for improvement. …”
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“…DESIGN, SETTING, AND PARTICIPANTS: This prognostic study analyzed the DXA and VFA results of all individuals who underwent a VFA between March 31, 2010, and March 31, 2018, who were included in the Manitoba Bone Mineral Density Registry. These individuals were randomly assigned to either the development cohort or validation cohort. …”
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