Mostrando 41 - 60 Resultados de 12,438 Para Buscar '"Bory"', tiempo de consulta: 0.51s Limitar resultados
  1. 41
    “…BORIS (for brother of the regulator of imprinted sites), a paralogue of the transcription factor, CTCF, is a novel member of the cancer-testis antigen family. …”
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    “…The study assessed the radiological risks associated with the presence of natural and artificial radionuclides in the Bory Stobrawskie forests (PL). Using the conversion factors given by UNSCEAR and the measurements results of (232)Th series, (238)U series, (40)K, and (137)Cs specific activities in the 10-cm soil layer the values of absorbed dose (D) and the annual effective dose equivalent derived from terrestrial gamma radiation (E) were calculated. …”
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  4. 44
    “…While healthy somatic tissues express only CTCF, CTCF and BORIS are normally co-expressed in meiotic and post-meiotic germ cells, and aberrant activation of BORIS occurs in tumors and some cancer cell lines. …”
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    “…The animal model we constructed could be used to study the in vivo immunogenicity of the human BORIS sf2 in murine hepatoma cells. CONCLUSIONS: The animals bearing BORIS sf2/C68-positive tumors may serve as an animal model for studying the therapeutic potency and safety of HCC vaccine directed at the CT-antigen BORIS sf2.…”
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    “…OA was induced in 7-week-old Wistar rats by intra-articular injection of monosodium iodoacetate (MIA); subsequently, the rats underwent oral administration of Bifidobacterium longum BORI (B. BORI). The effects of B. BORI were examined in chondrocytes and an MIA-induced OA rat model. …”
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  9. 49
    “…Interestingly, the inhibition of DNA methylation, BORIS depletion, or CRISPR/Cas9-mediated deletion of the BORIS binding site leads to a splicing switch from cancer-specific PKM2 to normal PKM1 isoform. …”
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  11. 51
    “…This research is based on an up-to-date case study of how Chinese Internet users discussed the UK Prime Minister – Boris Johnson’s infection with COVID-19 in late March and early April 2020. …”
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    “…Here, we further tested the therapeutic efficacy of BORIS in a rat 13762 breast cancer model. We generated a recombinant VEE-VRP (Venezuelan Equine Encephalitis-derived replicon particle) vector-expressing modified rat BORIS lacking a DNA-binding domain (VRP-mBORIS). …”
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    “…Frequent amplification of the 20q13.2 region, which contains the BORIS gene, and expression of BORIS transcripts in diverse human tumors and cell lines have led to the hypothesis that aberrant expression of BORIS may play a role in tumorigenesis by interfering with CTCF functions. …”
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  16. 56
    “…The ages of a fruticose lichen of Usnea aurantiacoatra (Jacq.) Bory, from Fildes Peninsula, King George Island, Southwest Antarctic, were determined by radiocarbon ((14)C), and it is 1993–1996 at bottom and 2006–2007 at top of the lichen branch. …”
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  17. 57
    “…BORIS expression promotes cell immortalization and growth while CTCF has tumor suppressor activity; the expression pattern may reflect the reverse transcription silencing of BORIS. …”
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    “…RESULTS: Here we show that these two proteins co-occupy a specific subset of regulatory elements consisting of clustered CTCF binding motifs (termed 2xCTSes). BORIS occupancy at 2xCTSes is largely invariant in BORIS-positive cancer cells, with the genomic pattern recapitulating the germline-specific BORIS binding to chromatin. …”
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