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  1. 14621
    “…After a three (3d)- or seven-day-culture (7d) on the two devices, we found both cell types growing three-dimensionally within multicellular spheroids (MCS) and also cells remaining adherent (AD) to the culture flask, while 1g-control cultures only formed adherent monolayers, unless the bottom of the culture dish was covered by agarose. …”
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    Common Effects on Cancer Cells Exerted by a Random Positioning Machine and a 2D Clinostat
  2. 14622
    por Ross, John
    Publicado 2015
    “…Gap changes were decomposed to show how the gaps can either diminish or grow due to either the bottom or top quintile, or both. In addition, bivariate correlation analysis was conducted to examine the relationship of the gaps, and of contraceptive use by the poor, to national family planning program efforts. …”
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    Improved Reproductive Health Equity Between the Poor and the Rich: An Analysis of Trends in 46 Low- and Middle-Income Countries
  3. 14623
    “…A combination of step-down and bottom-up costing methodologies was used. Sensitivity analysis was conducted to test the uncertainty around estimated parameters and model assumptions. …”
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    Matching comprehensive health insurance reimbursements to their real costs: the case of antenatal care visits in a region of Peru
  4. 14624
    por Andersen, Hege, Røvik, Kjell Arne
    Publicado 2015
    “…Among these were a problem, not method focus, a bottom-up approach, the need of internal consultants, credibility, realism and patience. …”
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    Lost in translation: a case-study of the travel of lean thinking in a hospital
  5. 14625
    “…In this Account, we demonstrate that the sol–gel process represents a powerful “bottom-up” strategy for creating nanostructured materials that tackles the problems mentioned above. …”
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    Noble Metal Aerogels—Synthesis, Characterization, and Application as Electrocatalysts
  6. 14626
    “…At each age, children were allocated a value of 0/1/2 according to third of the distribution (bottom/middle/top) their diet quality score was in; values were summed to calculate an overall diet quality index (DQI) for early childhood (range 0–8). …”
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    Diet quality across early childhood and adiposity at 6 years: the Southampton Women's Survey
  7. 14627
    “…Data are taken from a 2004 house-to-house survey of urban households within the bottom 20th percentile of income distribution within seven states in Mexico. …”
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    Obesity-Related Behaviors among Poor Adolescents and Young Adults: Is Social Position Associated with Risk Behaviors?
  8. 14628
    “…To validate these findings, 200 roosters had their genetic merit predicted from the ASE SNPs only, and the top 30 and bottom 30 ranked roosters were reciprocally mated to random hens. …”
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    Fine mapping of QTL and genomic prediction using allele-specific expression SNPs demonstrates that the complex trait of genetic resistance to Marek’s disease is predominantly determined by transcriptional regulation
  9. 14629
    por Song, Weiguo, Francis, Joseph T.
    Publicado 2015
    “…Thus, these results suggest that tactile input is dominantly transmitted along the ascending direction from VPL to S1, and the sensory input is suppressed during movement through a bottom-up strategy within the gamma-band during passive movement.…”
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    Gating of tactile information through gamma band during passive arm movement in awake primates
  10. 14630
    “…The goal of this study was therefore to identify the molecular processes underpinning neurodegeneration in EGS. Here, we use a bottom-up approach beginning with the application of modern proteomic tools to the analysis of cranial (superior) cervical ganglion (CCG, a consistently affected tissue) from EGS-affected patients and appropriate control cases postmortem. …”
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    Proteomic Profiling of Cranial (Superior) Cervical Ganglia Reveals Beta-Amyloid and Ubiquitin Proteasome System Perturbations in an Equine Multiple System Neuropathy
  11. 14631
    “…In analyses comparing the top and bottom tertiles, cholesterol efflux capacity was significantly and inversely associated with incident coronary heart disease events, independent of age, sex, diabetes, hypertension, smoking and alcohol use, waist:hip ratio, BMI, LDL cholesterol concentration, log-triglycerides, and HDL cholesterol or apoA-I concentrations (odds ratio 0·64, 95% CI 0·51–0·80). …”
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    Association of HDL cholesterol efflux capacity with incident coronary heart disease events: a prospective case-control study
  12. 14632
    “…METHODS: Cost categories were identified through a bottom-up method. The Dutch 3-level 5-dimensional EuroQol (EQ-5D-3L) was used to calculate utilities. …”
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    The burden of stroke in the Netherlands: estimating quality of life and costs for 1 year poststroke
  13. 14633
    “…RESULTS: During the last 2 months of treatment, the largest savings could be expected for community-DOT; on average USD 17,351-18,203 and USD 43,660-45,856 (bottom-up and top-down estimates) per clinic. Savings to patients could also be expected as the median (interquartile range) patient-related costs during the two last months were USD 108 (13–291), USD 93 (36–239) and USD 11 (7–126), respectively for SAT, facility-DOT and community-DOT. …”
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    Shortened first-line TB treatment in Brazil: potential cost savings for patients and health services
  14. 14634
    “…After adjustment for established risk factors, both GRS27 and GRS50 were associated with incident CHD [hazard ratio (HR) = 1.70 for high (top quintile) vs. low (bottom quintile) of GRS27; 95% confidence interval (CI): 1.48–1.94; P(trend) = 1.6 × 10(−15) and HR = 1.92 for GRS50; 95% CI: 1.67–2.20; P(trend) = 6.2 × 10(−22)]. …”
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    Risk prediction by genetic risk scores for coronary heart disease is independent of self-reported family history
  15. 14635
    “…BACKGROUND: The success of genome-scale models (GEMs) can be attributed to the high-quality, bottom-up reconstructions of metabolic, protein synthesis, and transcriptional regulatory networks on an organism-specific basis. …”
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    Systems biology of the structural proteome
  16. 14636
    “…In analyses unadjusted for objective socioeconomic status (SES) measures such as income, education or occupation, the pooled OR comparing the bottom versus the top of the SSS ladder was 1.82 (95% CI 1.10 to 2.99) for CAD, 1.88 (95% CI 1.27 to 2.79) for hypertension, 1.90 (95% CI 1.25 to 2.87) for diabetes, 3.68 (95% CI 2.03 to 6.64) for dyslipidaemia and 1.57 (95% CI 0.95 to 2.59) for obesity. …”
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    Association between subjective social status and cardiovascular disease and cardiovascular risk factors: a systematic review and meta-analysis
  17. 14637
    “…Average CRs were 0.009 mm/yr for five central processing facility (CPF) waters, which had no APB or SRB due to weekly biocide treatment and 0.036 mm/yr for 2 CPF tank bottom sludges, which had high numbers of APB (10(6)/ml) and SRB (10(8)/ml). …”
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    Use of Homogeneously-Sized Carbon Steel Ball Bearings to Study Microbially-Influenced Corrosion in Oil Field Samples
  18. 14638
    “…We confirm substrate specificity of fungal Xeg1 towards xyloglucan by heterologous expression in yeast and show that xyloglucanase activity is higher in the oldest, bottom layers of fungus gardens and in discarded debris material than in the upper and middle layers of fungus gardens. …”
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    Ant mediated redistribution of a xyloglucanase enzyme in fungus gardens of Acromyrmex echinatior
  19. 14639
    “…Cryptocaryon irritans that fall to the seabed or aquarium bottom in winter can form “dormant tomonts” and wake up when the temperature rises the next year. …”
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    Transcriptome analysis of dormant tomonts of the marine fish ectoparasitic ciliate Cryptocaryon irritans under low temperature
  20. 14640
    “…In multivariate regression, being in the bottom ten percent of households (OR: 1.27, 95 % CI: 0.85-1.87) or being interviewed during the rainy season (OR: 1.61, 95 % CI: 1.24-2.09) was positively associated with acute lower respiratory infections, while urban residence (OR: 0.58, 95 % CI: 0.38-0.88) and being age 24–59 months versus 0–11 months (OR: 0.53, 95 % CI: 0.40-0.69) was negatively associated with acute lower respiratory infections. …”
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    Social, economic and environmental risk factors for acute lower respiratory infections among children under five years of age in Rwanda
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