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  1. 14721
    “…Here, we proposed a new, bottom-up conceptual paradigm: The Energy Homeostasis Principle, where the balance between energy income, expenditure, and availability are the key parameters in determining the dynamics of neuronal phenomena found from molecular to behavioral levels. …”
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    The Energy Homeostasis Principle: Neuronal Energy Regulation Drives Local Network Dynamics Generating Behavior
  2. 14722
    “…Interestingly, the body fat percentage of M. expansa, which lacks the ability to synthesize fatty acids, is as high as 78% (dry weight) and all of the proglottids of M. expansa exhibit a dynamic developmental process from top to bottom. The aim of this paper is to identify the molecular basis of this high body fat percentage, the dynamic expression of developmental genes and their expression regulation patterns. …”
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    Evaluation of dynamic developmental processes and the molecular basis of the high body fat percentage of different proglottid types of Moniezia expansa
  3. 14723
    “…Furthermore, the vibration amplitude in the Y-direction (left-right) was greatest and least in the Z-direction (top-bottom). The frequency of cyclic loading closest to the resonant frequency resulted in a maximum value of peak-to-peak vibrational displacement. …”
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    Differential response to vibration of three forms of scoliosis during axial cyclic loading: a finite element study
  4. 14724
    “…For the health system costs, a bottom-up costing methodology was used. Data on all resources (capital and recurrent) utilized for the delivery of cardiac care services for valvular heart disease for 1 year were collected. …”
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    Cost of Treatment of Valvular Heart Disease at a Tertiary Hospital in North India: Policy Implications
  5. 14725
    “…Cost was calculated from the patient’s perspective using a bottom-up methodology. The direct costs for each patient and indirect costs for each patient and their attendants were calculated. …”
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    Type 2 diabetes mellitus in Bangladesh: a prevalence based cost-of-illness study
  6. 14726
    “…CONCLUSIONS: The results indicated that small scale spatial segregation of foraging habitats is not driven by bottom-up processes. It is therefore important to also consider other potential drivers, e.g. competition, information transfer, and memory, to understand animal foraging decisions and movements.…”
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    Preferred, small-scale foraging areas of two Southern Ocean fur seal species are not determined by habitat characteristics
  7. 14727
    “…Therefore, reliable synthetic methods are required to precisely control these structural features. In this regard, bottom-up organic synthesis provides an indispensable way to achieve structurally well-defined heteroatom-doped nanographenes. …”
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    Heteroatom-Doped Nanographenes with Structural Precision
  8. 14728
    “…The risk of BC was lower by 88% (OR: 0.12; 95% Cl: 0.02–0.88; p < 0.05) in the upper tertile of the serum ‘Iron-Calcium’ profile compared to the bottom tertile, lower by 67% (OR: 0.33; 95% Cl: 0.11–0.97; p < 0.05) at the level of serum 25(OH) vitamin D ≥24.6 ng/mL and lower by 68% (OR: 0.32; 95% Cl: 0.11–0.91; p < 0.05) at the level of serum calcium ≥9.6 mg/dL. …”
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    Serum ‘Vitamin-Mineral’ Profiles: Associations with Postmenopausal Breast Cancer Risk Including Dietary Patterns and Supplementation. A Case-Control Study
  9. 14729
    “…Disks were attached to right and left bedrails, under bed, call button, chair armrest, floor near device, table top, table bottom, floor far from device, toilet seat and grab bar and sink handle in a mock 6.4 × 4.1-meter hospital room with a 1.5 × 2.4-meter bathroom. …”
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    1221. Comparison of the Antimicrobial Efficacy of Mobile Ultraviolet Light Devices in a Simulated Patient Room
  10. 14730
    “…The most disadvantaged neighborhoods were categorized as those in the upper 35 percentile, while the least disadvantaged was defined as those in the bottom 65% of national ADI rankings. We evaluated the relationship between ADI percentile and 30-day readmission risk using multivariate logistic regression, controlling for key patient demographics, comorbidities, and hospital/stay characteristics. …”
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    2377. Social Determinants Impact Readmission Following Clostridioides difficile-Related Index Hospital Stay in Medicare Patients
  11. 14731
    “…The burrowing assay methodology involves loading animals at the bottom of well plates, casting a liquid-phase of Pluronic on top that solidifies via a modest temperature upshift, enticing animals to reach the surface via chemotaxis to food, and quantifying the relative success animals have in reaching the chemoattractant. …”
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    Pluronic gel-based burrowing assay for rapid assessment of neuromuscular health in C. elegans
  12. 14732
    “…Direct costs and indirect costs were measured by using the bottom-up approach. Data were entered into Epi-Info version 7 and imported to SPSS version 20 for analysis. …”
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    The costs of traumatic head injury and associated factors at University of Gondar Specialized Referral Hospital, Northwest Ethiopia
  13. 14733
    “…LAP index showed the highest area under the receiver operating characteristic curve (0.728) to detect individuals with insulin resistance defined as the bottom quartile of insulin-stimulated glucose disposal, followed by TG/HDL-C ratio (0.693), TyG index (0.688) and VAI (0.688). …”
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    Relationships of surrogate indexes of insulin resistance with insulin sensitivity assessed by euglycemic hyperinsulinemic clamp and subclinical vascular damage
  14. 14734
    “…The network compactness is found to increase as one goes from top level to bottom level of the network organization.…”
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    Methodology of predicting novel key regulators in ovarian cancer network: a network theoretical approach
  15. 14735
    “…EVs generated by HEI-OC1 cells were divided by size into two fractions, small (≤150 nm diameter) and large (>150 nm diameter), and loaded with aspirin, lipoxin A4, resolvin D1, and the polyunsaturated fatty acids (PUFA) arachidonic, eicosapentaenoic, docosahexanoic, and linoleic. Bottom-up proteomics revealed a differential distribution of selected proteins between small and large vesicles. …”
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    Extracellular Vesicles From Auditory Cells as Nanocarriers for Anti-inflammatory Drugs and Pro-resolving Mediators
  16. 14736
    “…When combined with data from deeper water deposits (Kennecott Point) far to the southwest, it would appear a very broad area of northeastern Panthalassa experienced anoxic to euxinic bottom water conditions in the direct lead up to the end-Triassic mass extinction. …”
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    Uppermost Triassic phosphorites from Williston Lake, Canada: link to fluctuating euxinic-anoxic conditions in northeastern Panthalassa before the end-Triassic mass extinction
  17. 14737
    “…The integration of the electrodes at the bottom of the conventional microwell plates ensures that the motions of the liquid flows in the wells can be controlled through the application of high frequency AC current along these electrodes. …”
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    Electrokinetic Mixing for Improving the Kinetics of an HbA1c Immunoassay
  18. 14738
    “…Rich information derived from the day-to-day, working healthcare professional is integral to shaping future practices going forward. The bottom up, iterative design adopted in this study provides an approach to tap into this information.…”
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    How prepared are healthcare professionals for delivering physical activity guidance to those with diabetes? A formative evaluation
  19. 14739
    “…One innovative stigma reduction method is participatory video (PV), whereby marginalized people come together to script, film and produce bottom-up educational videos about shared issues. …”
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    Can participatory video reduce mental illness stigma? Results from a Canadian action-research study of feasibility and impact
  20. 14740
    “…We hypothesize that these bottom-up and top-down forces created an “ectothermic vise” on forage species leading to their system-wide scarcity and resulting in mass mortality of murres and many other fish, bird and mammal species in the region during 2014–2017.…”
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    Extreme mortality and reproductive failure of common murres resulting from the northeast Pacific marine heatwave of 2014-2016
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