“…Crowdsourcing contests provide an innovative bottom-up way to solicit community feedback on clinical trials in order to enhance community engagement. …”
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“…Our results demonstrate that a bottom-up approach, which extends the single neuronal dynamics model based on empirical observations into a neural mass dynamics model and integrates structural connectivity, effectively reveals both macroscopic fast, and slow resting-state network dynamics.…”
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“…A total of 54 signs were of value in defining a latent structure consisting of seven principal components (termed “exit frustration,” “social panic,” “elimination,” “redirected frustration,” “reactive communication,” “immediate frustration,” “noise sensitivity”), which divided the population in four clusters (termed “exit frustration,” “redirected reactive,” “reactive inhibited” and “boredom” related SRPs) with 11 sub-clusters (3, 3, 3, and 2, respectively). We used a bottom-up data-driven approach with numerous quality checks for the definition of robust clusters to provide a robust methodology for nosological studies in veterinary behavioral medicine, that can extend our understanding of the nature of problems beyond SRPs. …”
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“…BACKGROUND: Employees dealing with job demands such as high workload and permeable work-life boundaries could benefit from bottom-up well-being strategies such as off-job crafting. …”
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“…Keratinocytes in culture need laminin‐332 for adhesion and migration and therefore deposit it on the bottom of the culture dish. What does this study add? …”
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“…The results showed that the LNC in the bottom of rice canopy was more susceptible to different N rates, and changes in the LNC with the relative canopy height could be simulated by an exponential model. …”
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“…Women in the top compared with the bottom quartile of self-reported physical activity had a reduced risk of both premenopausal (RR 0.75; 95% CI 0.60–0.93) and postmenopausal breast cancer (RR 0.87; 95% CI 0.78–0.98), after adjusting for adiposity. …”
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“…Previous work with homomeric ASIC1a implicates conserved leucine (L7′) and consecutive glycine-alanine-serine (GAS belt) residues near the middle, and conserved negatively charged (E18′) residues at the bottom of the pore in ion permeation and/or selectivity. …”
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“…Poyang Lake is a typical seasonal lake linked to the Yangtze River and is significantly affected by water level fluctuations. Bottom water was collected from 12 sampling sites: seven inundated for the whole year (inundated areas) and five drained during the dry season (emerged areas). …”
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“…After adjusting for potential confounding factors, per SD increase of MHR caused a 25.2% additional risk for hyperuricemia, and the top quartile of MHR had an 82.9% increased risk for hyperuricemia compared with the bottom quartile. Additionally, smooth curve fitting and subgroup analyses showed a linear and robust association between MHR and prevalent hyperuricemia respectively. …”
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“…Here, we used model-based functional magnetic resonance imaging (fMRI) to characterize learning from social prediction errors in 61 participants drawn from a population-based sample (n = 2402) who were recruited on the basis of being in the bottom or top 10% of self-esteem scores. Participants performed a social evaluation task during fMRI scanning, which entailed predicting whether other people liked them as well as the repeated provision of reported feelings of self-worth. …”
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“…The top 25% of Q1 performers increased their average numbers triaged from Q1–36.5 to Q4–40.3 (ie, a statistically insignificant increase of 3.8 patients per shift [p = 0.07]). The bottom 25% of Q1 performers, on the other hand, increased their averages from Q1–22.4 to Q4–34.5 (ie, a statistically significant increase of 12.2 patients per shift [p = 0.0013]). …”
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“…Data were analysed using ‘top-down’ and ‘bottom-up’ thematic coding. RESULTS: Interviewees reported an improvement in the surgical skills and confidence of NPCs, as well as better teamwork. …”
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“…The contemporary focus in this paradigm has been gut → brain (“bottom-up”), in which the gut-microbiome, and its perturbations, affects one’s psychological state-of-mind and behavior, and is pivotal in neurodegenerative disorders. …”
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“…For Zinnwald quartz, IR absorption spectra reveal different lithologies due to changes of the OH defect inventory, enabling a subdivision of the granitic body: (1) hydrothermal greisen quartz of the uppermost part of the intrusion have low OH defect contents (average of 15 µg/g H(2)O); (2) zinnwaldite granite quartz vary strongly in defect content and show the highest content of the dataset (10–70 µg/g H(2)O); (3) quartz from an underlying biotite granite have slightly lower, but very uniform contents down to the bottom of the borehole at 1600 m (average 20 µg/g H(2)O). …”
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“…RESULTS: The treatment with Ad-SGE-REIC showed the number of malignant glioma cells attached to the bottom of culture wells was significantly reduced in a time-dependent manner. …”
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“…In conclusion, our data suggest that fluid processing, which involves “online,” bottom-up, cognitive processing, predicts value-based decision-making amongst older adults, while crystallized intelligence, which relies on “offline” previously acquired knowledge, does not. …”
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“…The discrimination of the PRS was similar between the top and bottom quartiles of Indigenous American ancestry. …”
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“…Two modalities were tested: a single wipe motion from top to bottom or vigorous wiping (n = 6 for each modality). …”
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“…RESULTS: Here we present advantages and disadvantages of bottom-up proteomics, using MALDI-TOF/TOF tandem mass spectrometry, for culture-independent identification of uropathogens (e.g. directly from urine samples). …”
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