“…RCS analyses demonstrated significant non-linear trends of the associations between dietary GI and CF and T2DM risk (both P-overall < 0.001, P-nonlinear = 0.001), and threshold analyses showed that T2DM risk decreased and reached the bottom when dietary GI was 74.5 (73.4, 75.6) and CF was 27.3 (25.1, 29.6) (both P-log likelihood ratio < 0.001). …”
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“…Imaging revealed constant gas exchange via the main incision, with CO(2) outflow via bottom and air inflow via the top of the incision. …”
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“…Thus, clover used by cereal growers for other services (weeds reduction, nitrogen supply, and soil cover), would participate to lower the risks associated to the presence of BYDV vectors through a bottom-up regulation of aphid populations within the field. …”
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“…When the cell proliferation reached 80%–90% of the bottom area of the culture flask, it was resuspended, passaged, frozen, and resuscitated according to experimental needs. …”
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“…The implementation has been driven by a bottom-up strategy. A deliberate and standardized strategy is needed to ensure full implementation of PCC into clinical curricula in higher education.…”
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“…The indicator was significantly associated with incidence of T2DM in the prospective cohort with HRs (95% CIs) from bottom quartile to top quartile being 1,1.21 (0.82–1.77), 1.60 (1.12–2.30), 2.04 (1.42–2.94). …”
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“…After osteotomy, the anteroposterior diameter was 3.73 ± 0.32 cm, the transverse diameter was 2.46 ± 0.27 cm, and the ratio of anteroposterior diameter to transverse diameter was 1.53. In the bottom view, the shape after osteotomy is rectangular. …”
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“…A metal matrix was placed at the bottom of the box for each restoration, creating a cervical gap of about 100 μm wide. …”
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“…Only moose demonstrated a positive behavioral association (i.e., longer events) with vegetation productivity (16‐day NDVI), suggesting that for other species bottom‐up influences of forage availability were generally weaker than top‐down influences from predation risk. …”
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“…Obtaining good-quality sputum from the bottom of the respiratory tract of children is challenging. …”
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“…CONCLUSIONS: In this work, bottom-up proteomics, a powerful tool to interrogate tissue composition, was used for the first time to quantify and compare the proteome of a developing engineered tissue to a recipient tissue. …”
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“…Pre-operative HbA1c was an independent predictor of AKI after adjustment for some clinical variables (OR comparing top to bottom quintiles 5.02, 95% CI, 1.90 to 13.24, P < 0.001 for trend; OR per percentage point increment in HbA1c 1.20, 95% CI, 1.07 to 1.33). …”
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“…The H. alternans life history in Lake Superior begins in mid-summer shortly after oviposition, which features females swimming to surf-exposed lake bottom substrates. Larval development takes approximately 10 months, but most of it occurs during their first 100 days. …”
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“…The median levels of hsCRP within 24 hours, between 24 and 72 hours and between 72 hours and 8 days were 2.01, 1.72, and 1.72 mg/L, respectively (P < 0.05). Compared with the bottom quartile, patients in the top quartile measured within 72 hours were at increased risk of recurrent stroke (<24 hours: adjusted hazard ratio [HR], 1.57 [95% CI, 1.05–2.35], P = 0.03; 24–72 hours: adjusted HR, 1.60 [95% CI, 1.18–2.17], P = 0.003). …”
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“…During the forecasting period, a Water Alternating Gas (WAG) injection ratio of 1:3 was utilized with a baseline bottom-hole pressure constraint of 5500 psi for 20 years. …”
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“…RESULTS: We observed a continual decline in gastric cancer risk according to the level-up of vitamin D intake in both genders, men, and women [Fifth vs. bottom quintile, OR, 95%CI: 0.68 (0.53, 0.86), OR, 95%CI: 0.72 (0.53, 0.97), OR, 95%CI: 0.58 (0.38, 0.89), respectively. …”
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“…RESULTS: Our findings reveal, first, a need for intersectoral collaboration between governments and affected populations for inclusive and sustainable NTD solutions. Second, a ‘bottom-up’ approach that enhances capacity building, sensitization, and behaviour change for improved uptake of NTD interventions. …”
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“…A final step consists of incubating recombinant M(pro) with natural extracts and identifying compounds adducted to the residues within the M(pro) active site by bottom-up proteomic analysis (nano-LC-HRMS). Data analysis is based on two complementary strategies: (i) a targeted search applied by setting the adducted moieties identified as Michael acceptors of Cys as variable modifications; (ii) an untargeted approach aimed at identifying the whole range of adducted peptides containing Cys145 on the basis of the characteristic b and y fragment ions independent of the adduct. …”
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“…After dividing eGDR into groups, the top group had a 58.9% risk reduction than the bottom group. Furthermore, smooth curve fitting demonstrated that the correlation between eGDR and prevalent IHD was linear in the whole range of eGDR. …”
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“…Two different methodologies have been applied: a bottom-up approach was applied to Spanish institutional data concerning contagions/hospitalizations/deaths and the extent of public green areas for each responder to an official questionnaire in the frame of a nationwide survey (with detailed data granularity per province) containing specific georeferenced information; a top-down approach was used for Italy, starting from the official figures of contagions/hospitalizations/deaths of each province and linking them to the OECD statistics about the extension of public green areas in the different areas. …”
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