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  1. 15261
    “…First, regarding the concept of the triple bottom line, total cost, environmental emissions, and job opportunities are considered to cover the criteria of sustainability. …”
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    A sustainable supply chain network considering lot sizing with quantity discounts under disruption risks: centralized and decentralized models
  2. 15262
    “…Results: UA triggered NRK-52E cell injury, as evidenced by morphological changes, detachment of cells from the bottom, cell swelling, large bubbles blowing from cell membrane and loss of cell viability. …”
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    Total extract of Abelmoschus manihot L. alleviates uric acid-induced renal tubular epithelial injury via inhibition of caspase-8/caspase-3/NLRP3/GSDME signaling
  3. 15263
    “…The most time-effective method was growing cells in spheroids using low-adhesive U-bottom plates. However, not every cell type grew into a 3D model using the the other methods of hanging drop or poly-HEMA. …”
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    3-Dimensional mesothelioma spheroids provide closer to natural pathophysiological tumor microenvironment for drug response studies
  4. 15264
    por Jing, Lijun, Du, Yabing, Fu, Denggang
    Publicado 2022
    “…Patients were classified into GI-like and genomic stable (GS)-like groups according to the top 25% and bottom 25% cumulative counts of somatic mutations. …”
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    Characterization of tumor immune microenvironment and cancer therapy for head and neck squamous cell carcinoma through identification of a genomic instability-related lncRNA prognostic signature
  5. 15265
    “…Costs were calculated using a bottom–up approach and involving cost calculation on a granular level. …”
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    Perioperative inappropriate red blood cell transfusions significantly increase total costs in elective surgical patients, representing an important economic burden for hospitals
  6. 15266
    “…The homogeneity of spatial distribution (top, middle and bottom of the eIBUB) was comparable between modalities. …”
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    Feasibility of pressurized intra peritoneal aerosol chemotherapy using an ultrasound aerosol generator (usPIPAC)
  7. 15267
    “…We typically attempt to place the tube at the bottom of the thoracic cavity to consider the effects of gravity; however, the effectiveness of this practice is not well-defined. …”
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    The relationship between chest tube position in the thoracic cavity and treatment failure in patients with pleural infection: a retrospective cohort study
  8. 15268
    “…Relative difference between forecasted and observed STEMI numbers (above figure), the relative risk of in-hospital mortality (middle figure) as well as number of new hospital admissions for COVID-19 per million inhabitants according to Roser et al.(27) (bottom figure). [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00392-022-02102-2.…”
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    COVID-19 pandemic affects STEMI numbers and in-hospital mortality: results of a nationwide analysis in Germany
  9. 15269
    “…Individuals with top 10% of PRS for elevated cystatin C, urate, and microalbuminuria had 28% to 43% higher risks of severe COVID‐19 than individuals with bottom 30% PRS (p < 0.05). Tipping‐point analyses further supported that severe COVID‐19 could occur even when the values of cystatin C, urate (male), and microalbuminuria were within their normal value ranges (OR >1.1, p < 0.05). …”
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    Impaired kidney function biomarkers and risk of severe COVID‐19: Analysis of population‐based cohort data
  10. 15270
    “…The findings point to a number of preconditions for large-scale introduction, including the need for support—both financially and organizationally—bottom-up involvement of teachers, children and parents and freedom to adapt the program.…”
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    Which factors promote and prohibit successful implementation and normalization of a healthy school lunch program at primary schools in the Netherlands?
  11. 15271
    “…In a meta-analysis of 16 population-based prospective cohort studies (including the current study) comprising 180,920 participants, the pooled multivariable adjusted relative risks (95% CIs) comparing the top vs bottom thirds of HGS levels were as follows: 0.58 (0.52–0.65) for cognitive impairment; 0.37 (0.07–1.85) for cognitive decline; 0.73 (0.62–0.86) for dementia; 0.68 (0.53–0.87) for AD; and 0.48 (0.32–0.73) for vascular dementia. …”
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    Handgrip strength and risk of cognitive outcomes: new prospective study and meta-analysis of 16 observational cohort studies
  12. 15272
    “…On physical examination, she had some dysmorphic features that were suggestive of a syndromic condition: prominent ear lobes, broad and flat nasal bridge, a single prominent tooth at the center of the bottom gum line, long palpebral fissures with upward curvature at the lateral edges, prominent finger pads and neurodevelopmental delay. …”
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    PSUN339 Persistent Hypoglycemia and Hyperinsulinism in a Patient With Kabuki Syndrome Type 1.
  13. 15273
    “…The odds of PS were doubled in people on the top tertile of DII (OR = 2.49, 95% (CI) = 1.11–5.58) and second tertile of EDII (OR = 2.29, 95% (CI) = 1.03–5.07) relative to bottom tertiles after adjusting for confounders. The relationships between index scores and HGS were simply significant in the adjusted model of EDII and HGS (B = -0.49, p = 0.04). …”
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    Association between dietary inflammatory potential and the probable sarcopenia among community-dwelling older adults: a cross-sectional study
  14. 15274
    “…Such superatomic icosahedral-C(n)B(12-n) stuffed borafullerenes and borospherenes with spherical aromaticity may serve as embryos to form bulk boron allotropes and their carbon-boron binary counterparts in bottom-up approaches.…”
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    Superatomic icosahedral-C(n)B(12-n) (n = 0, 1, 2) Stuffed mononuclear and binuclear borafullerene and borospherene nanoclusters with spherical aromaticity
  15. 15275
    por Miller, Roslyn
    Publicado 2022
    “…Surgical correction of the 'rocker bottom deformity has evolved. Minimally invasive surgical techniques utilising beams and bolts for a 'super-construct' to correct the Charcot deformity is possible through percutaneous incisions. …”
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    A 5-Year Follow-Up of Neuropathic Minimally Invasive Surgeries with Superconstructs for Mid-Foot Charcot Deformity
  16. 15276
    “…However, conformity between SPECT and CT at the bottom of the lung is generally low. This study aims to investigate the progression of conformity between lung perfusion SPECT and lung CT using a breathing synchronization software. …”
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    Evaluation of lung perfusion by using lung perfusion SPECT and lung CT with breathing synchronization software
  17. 15277
    “…In this sample, contrast agent had permeated through the drilling site to the bottom and some sub-site permeation was observed. …”
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    How Does Surgical Technique Affect Fluid Permeability? A Laboratory Study Comparing Nanofracture, Microfracture and Fine Wire Drilling Approaches
  18. 15278
    “…Internode-specific QTL analyses detected both major QTLs of chromosomes 3B and 3D across internodes, from top to bottom of the stalk, but minor QTLs were largely detected in upper or middle internodes. …”
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    QTL analysis identified two major all-internodes solidness loci from a completely solid-stemmed spring wheat line
  19. 15279
    “…The features are sorted from top to bottom by their mean absolute SHAP values (higher interpreted as more contributing). …”
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    1162. A data-driven approach to predict plasma leakage using explainable machine learning
  20. 15280
    “…Two weeks after injury, the thickness of the ganglion cell region (GCL to IPL) and photoreceptor layer (bottom of the OPL to top of the RPE) were measured using OCT. …”
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    Assessment of outer retinal thickness and function in mice after experimental optic nerve trauma
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