“…In multivariable analyses, 18:2n–6 was positively associated with ICH (HR = 2.33 [95% CIs 1.41, 3.82] for top versus bottom quintile, P(trend) = 0.007), but inversely associated with IS (0.69 [0.53,0.90], P(trend) = 0.027), while 20:3n-6 was positively associated with risk of IS (1.64 [1.32,2.04], P(trend) < 0.001), but not with ICH. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Active proliferation might be associated with enhanced expression levels in several factors (JNK pathway: jun-D; TGF-β pathway: decapentaplegic, glass bottom boat; insulin pathway: insulin-like peptides from the fat body; Wnt pathway: wntless, TCF/Pangolin). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…There is a need for a culture shift in assessing careers and “productivity” in academia, and this requires collaborative top-down and bottom-up approaches. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13063-022-06624-y.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…All but 2 patient characteristics (race and diagnosis of depression) were well-balanced between the top and bottom quartiles of the instrumental variable. Regarding 1-year outcomes, compared with patients undergoing gastric bypass, patients undergoing sleeve gastrectomy had a lower 1-year risk of mortality (0.9%; 95% CI, 0.8%-1.1% vs 1.7%; 95% CI, 1.3%-2.0%), complications (11.6%; 95% CI, 10.9%-12.3% vs 14.1%; 95% CI, 13.0%-15.3%), emergency department visits (48.3%; 95% CI, 46.9%-49.8% vs 53.6%; 95% CI, 52.3%-55.0%), hospitalization (23.4%; 95% CI, 22.4%-24.4% vs 26.5%; 95% CI, 25.1%-28.0%), and reinterventions (8.7%; 95% CI, 8.0%-9.4% vs 12.2%; 95% CI, 11.2%-13.3%). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Financial and economic costs of providing care for childhood illnesses were investigated from the provider perspective by combining a top-down and bottom-up approach to estimate unit costs and annual total costs for different types of visits for these illnesses. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The biggest diversity appeared in the fruit-related characteristics, i.e., stem end fruit shape, bottom end fruit shape, fruit shape, and fruit skin colour at the table and harvest maturity. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The prevalence-based and the bottom-up approaches were also used to collect the cost information and calculate the costs, respectively. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Controlling for caste, religion, gender, age, marital status and years of education, we found psychological distress is statistically higher among patients belonging to this bottom SES. CONCLUSIONS: We found that pain severity, psychological distress and perceived low SES are negatively associated with the desire to live in advanced cancer patients. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In ICG group, the average vertical distances between the top and bottom of the fluorescent edge and neoplastic edge were 2.65±0.58 and 2.67±0.65 cm, respectively. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…EC was found to be more ‘cost-effective’ than NC, with an ICER in the bottom right quadrant of the cost-effectiveness plane—indicating that it offers greater benefits at lower costs. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Third, instead of commonly developed monolithic systems, we propose a new data sharing method for data harmonization that combines both divide-and-conquer and bottom-up approaches. Finally, an end-to-end LDC implementation is introduced with real-world examples. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The spheres were fixed to the bottom of each tube by a plastic grid, yielding one sphere free homogeneous region and one heterogeneous (S1, S2, or S3) region per tube. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The ablation studies showed that using the complete CT study in the pipeline resulted in greater classification performance, restating that relevant COVID-19 patterns cannot be ignored towards the top and bottom of the lung volume. DISCUSSION: The lung CT classification architecture introduced has shown that it can handle weakly-labeled, variable-sized and possibly sparse axial lung studies, reducing the need for expert annotations at a per-slice level. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We discuss and compare the state-of-the-art bottom-up and top-down routes for the synthesis of nanoporous graphene films. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this study, a metagenomic approach was used to characterize ARG types and their abundance in different habitats (rhizosphere soil, surface bulk soil, bottom bulk soil, and sediment) of riverine ecosystems in eastern China. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Retaining positive elements of such change required a judicious balance between managerial (top-down) and emergent (bottom-up) approaches. Perspectives on exposure foregrounded social and technical impediments to video consulting. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CATEGORY: Diabetes; Midfoot/Forefoot INTRODUCTION/PURPOSE: Charcot arthropathy is a debilitating condition often accompanied by rocker-bottom deformity and plantar ulcerations. Patients with this condition historically experienced poor results, with varying rates of postoperative wound complications, infection, and amputation. …”
Enlace del recurso
Enlace del recurso

“…A mixed methodology consisting of both bottom-up and top-down costing was used for data collection. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this study, a simple and inexpensive sol–gel method is described to extract mesoporous silica nanoparticles (MSNs) from UKMRC8 RH using the bottom-up approach. RHs treated with hydrochloric acid were calcinated to obtain rice husk ash (RHA) with high silica purity (> 98% wt), as determined by the X-ray fluorescence analysis (XRF). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…[Figure: see text] Antibiotic days of therapy (DOT) stratified by study period (top) and antibiotic (LOT) stratified by study period (bottom). CONCLUSION: An intervention of automatically changing stool culture testing to stool PCR testing did not result in a significant change in median DOT or LOT in hospitalized adult patients, nor did it result in a significant change in DOT or LOT incidence rate. …”
Enlace del recurso
Enlace del recurso