The involvement of physician assistants in inpatient care in hospitals in the Netherlands: a cost-effectiveness analysis

por Timmermans, Marijke J C, van den Brink, Geert T, van Vught, Anneke J A H, Adang, Eddy, van Berlo, Charles L H, van Boxtel, Kim, Braunius, Weibel W, Janssen, Loes, Venema, Alyssa, van den Wildenberg, Frits J, Wensing, Michel, Laurant, Miranda G H
Publicado 2017

The endosomal RIN2/Rab5C machinery prevents VEGFR2 degradation to control gene expression and tip cell identity during angiogenesis

por Kempers, Lanette, Wakayama, Yuki, van der Bijl, Ivo, Furumaya, Charita, De Cuyper, Iris M., Jongejan, Aldo, Kat, Marije, van Stalborch, Anne-Marieke D., van Boxtel, Antonius L., Hubert, Marvin, Geerts, Dirk, van Buul, Jaap D., de Korte, Dirk, Herzog, Wiebke, Margadant, Coert
Publicado 2021

Prime editing for functional repair in patient-derived disease models

por Schene, Imre F., Joore, Indi P., Oka, Rurika, Mokry, Michal, van Vugt, Anke H. M., van Boxtel, Ruben, van der Doef, Hubert P. J., van der Laan, Luc J. W., Verstegen, Monique M. A., van Hasselt, Peter M., Nieuwenhuis, Edward E. S., Fuchs, Sabine A.
Publicado 2020

Cerebral blood flow, blood supply, and cognition in Type 2 Diabetes Mellitus

por Jansen, Jacobus F. A., van Bussel, Frank C. G., van de Haar, Harm J., van Osch, Matthias J. P., Hofman, Paul A. M., van Boxtel, Martin P. J., van Oostenbrugge, Robert J., Schram, Miranda T., Stehouwer, Coen D. A., Wildberger, Joachim E., Backes, Walter H.
Publicado 2016

Androgen deprivation therapy for androgen receptor‐positive advanced salivary duct carcinoma: A nationwide case series of 35 patients in The Netherlands

por Boon, Eline, van Boxtel, Wim, Buter, Jan, Baatenburg de Jong, Robert J., van Es, Robert J. J., Bel, Miranda, Fiets, Edward, Oosting, Sjoukje F., Slingerland, Marije, Hoeben, Ann, Tesselaar, Margot E. T., Jonker, Marianne A., Flucke, Uta E., van der Graaf, Winette T. A., van Herpen, Carla M. L.
Publicado 2017

One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids

por Geurts, Maarten H., Gandhi, Shashank, Boretto, Matteo G., Akkerman, Ninouk, Derks, Lucca L. M., van Son, Gijs, Celotti, Martina, Harshuk-Shabso, Sarina, Peci, Flavia, Begthel, Harry, Hendriks, Delilah, Schürmann, Paul, Andersson-Rolf, Amanda, Chuva de Sousa Lopes, Susana M., van Es, Johan H., van Boxtel, Ruben, Clevers, Hans
Publicado 2023

International recommendations for a vascular access minimum dataset: a Delphi consensus-building study

por Schults, Jessica, Kleidon, Tricia, Chopra, Vineet, Cooke, Marie, Paterson, Rebecca, Ullman, Amanda J, Marsh, Nicole, Ray-Barruel, Gillian, Hill, Jocelyn, Devrim, İlker, Hammarskjold, Fredrik, Pedreira, Mavilde L, Bertoglio, Sergio, Egan, Gail, Mimoz, Olivier, van Boxtel, Ton, DeVries, Michelle, Magalhaes, Maria, Hallam, Carole, Oakley, Suzanne, Rickard, Claire M
Publicado 2021

Precancerous liver diseases do not cause increased mutagenesis in liver stem cells

por Nguyen, Luan, Jager, Myrthe, Lieshout, Ruby, de Ruiter, Petra E., Locati, Mauro D., Besselink, Nicolle, van der Roest, Bastiaan, Janssen, Roel, Boymans, Sander, de Jonge, Jeroen, IJzermans, Jan N. M., Doukas, Michail, Verstegen, Monique M. A., van Boxtel, Ruben, van der Laan, Luc J. W., Cuppen, Edwin, Kuijk, Ewart
Publicado 2021

Comprehensive single-cell genome analysis at nucleotide resolution using the PTA Analysis Toolbox

por Middelkamp, Sjors, Manders, Freek, Peci, Flavia, van Roosmalen, Markus J., González, Diego Montiel, Bertrums, Eline J.M., van der Werf, Inge, Derks, Lucca L.M., Groenen, Niels M., Verheul, Mark, Trabut, Laurianne, Pleguezuelos-Manzano, Cayetano, Brandsma, Arianne M., Antoniou, Evangelia, Reinhardt, Dirk, Bierings, Marc, Belderbos, Mirjam E., van Boxtel, Ruben
Publicado 2023

Elevated Mutational Age in Blood of Children Treated for Cancer Contributes to Therapy-Related Myeloid Neoplasms

por Bertrums, Eline J.M., Rosendahl Huber, Axel K.M., de Kanter, Jurrian K., Brandsma, Arianne M., van Leeuwen, Anaïs J.C.N., Verheul, Mark, van den Heuvel-Eibrink, Marry M., Oka, Rurika, van Roosmalen, Markus J., de Groot-Kruseman, Hester A., Zwaan, C. Michel, Goemans, Bianca F., van Boxtel, Ruben
Publicado 2022

Defects in 8-oxo-guanine repair pathway cause high frequency of C > A substitutions in neuroblastoma

por van den Boogaard, Marlinde L., Oka, Rurika, Hakkert, Anne, Schild, Linda, Ebus, Marli E., van Gerven, Michael R., Zwijnenburg, Danny A., Molenaar, Piet, Hoyng, Lieke L., Dolman, M. Emmy M., Essing, Anke H. W., Koopmans, Bianca, Helleday, Thomas, Drost, Jarno, van Boxtel, Ruben, Versteeg, Rogier, Koster, Jan, Molenaar, Jan J.
Publicado 2021

Associations between plasma kynurenines and cognitive function in individuals with normal glucose metabolism, prediabetes and type 2 diabetes: the Maastricht Study

por Bakker, Lieke, Ramakers, Inez H. G. B., van Boxtel, Martin P. J., Schram, Miranda T., Stehouwer, Coen D. A., van der Kallen, Carla J. H., Dagnelie, Pieter C., van Greevenbroek, Marleen M. J., Wesselius, Anke, Midttun, Øivind, Ueland, Per M., Verhey, Frans R. J., Eussen, Simone J. P. M., Köhler, Sebastian
Publicado 2021

Association of Type 2 Diabetes, According to the Number of Risk Factors Within Target Range, With Structural Brain Abnormalities, Cognitive Performance, and Risk of Dementia

por van Gennip, April C.E., Stehouwer, Coen D.A., van Boxtel, Martin P.J., Verhey, Frans R.J., Koster, Annemarie, Kroon, Abraham A., Köhler, Sebastian, van Greevenbroek, Marleen M.J., Wesselius, Anke, Eussen, Simone J.P.M., Backes, Walter H., Jansen, Jacobus F., Schram, Miranda T., Henry, Ronald M.A., Singh-Manoux, Archana, van Sloten, Thomas T.
Publicado 2021

Sister chromatid exchanges induced by perturbed replication can form independently of BRCA1, BRCA2 and RAD51

por Heijink, Anne Margriet, Stok, Colin, Porubsky, David, Manolika, Eleni Maria, de Kanter, Jurrian K., Kok, Yannick P., Everts, Marieke, de Boer, H. Rudolf, Audrey, Anastasia, Bakker, Femke J., Wierenga, Elles, Tijsterman, Marcel, Guryev, Victor, Spierings, Diana C. J., Knipscheer, Puck, van Boxtel, Ruben, Ray Chaudhuri, Arnab, Lansdorp, Peter M., van Vugt, Marcel A. T. M.
Publicado 2022

Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver

por Huch, Meritxell, Gehart, Helmuth, van Boxtel, Ruben, Hamer, Karien, Blokzijl, Francis, Verstegen, Monique M.A., Ellis, Ewa, van Wenum, Martien, Fuchs, Sabine A., de Ligt, Joep, van de Wetering, Marc, Sasaki, Nobuo, Boers, Susanne J., Kemperman, Hans, de Jonge, Jeroen, Ijzermans, Jan N.M., Nieuwenhuis, Edward E.S., Hoekstra, Ruurdtje, Strom, Stephen, Vries, Robert R.G., van der Laan, Luc J.W., Cuppen, Edwin, Clevers, Hans
Publicado 2015

A clinicopathological study and prognostic factor analysis of 177 salivary duct carcinoma patients from The Netherlands

por Boon, Eline, Bel, Miranda, van Boxtel, Wim, van der Graaf, Winette T. A., van Es, Robert J. J., Eerenstein, Simone E. J., Baatenburg de Jong, Robert J., van den Brekel, Michiel W. M., van der Velden, Lilly‐Ann, Witjes, Max J. H., Hoeben, Ann, Willems, Stefan M., Bloemena, Elisabeth, Smit, Laura A., Oosting, Sjoukje F., Jonker, Marianne A., Flucke, Uta E., van Herpen, Carla M. L.
Publicado 2018

Health burden in type 2 diabetes and prediabetes in The Maastricht Study

por Veugen, Marja G. J., Onete, Veronica G., Henry, Ronald M. A., Brunner-La Rocca, Hans-Peter, Koster, Annemarie, Dagnelie, Pieter C., Schaper, Nicolaas C., Sep, Simone J. S., van der Kallen, Carla J. H., van Boxtel, Martin P. J., Reesink, Koen D., Schouten, Johannes S., Savelberg, Hans H. C. M., Köhler, Sebastian, Verhey, Frans R., van den Bergh, Joop P. W., Schram, Miranda T., Stehouwer, Coen D. A.
Publicado 2022

In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels

por Rothgangl, Tanja, Dennis, Melissa K., Lin, Paulo J. C., Oka, Rurika, Witzigmann, Dominik, Villiger, Lukas, Qi, Weihong, Hruzova, Martina, Kissling, Lucas, Lenggenhager, Daniela, Borrelli, Costanza, Egli, Sabina, Frey, Nina, Bakker, Noëlle, Walker, John A., Kadina, Anastasia P., Victorov, Denis V., Pacesa, Martin, Kreutzer, Susanne, Kontarakis, Zacharias, Moor, Andreas, Jinek, Martin, Weissman, Drew, Stoffel, Markus, van Boxtel, Ruben, Holden, Kevin, Pardi, Norbert, Thöny, Beat, Häberle, Johannes, Tam, Ying K., Semple, Sean C., Schwank, Gerald
Publicado 2021

An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneity

por Calandrini, Camilla, Schutgens, Frans, Oka, Rurika, Margaritis, Thanasis, Candelli, Tito, Mathijsen, Luka, Ammerlaan, Carola, van Ineveld, Ravian L., Derakhshan, Sepide, de Haan, Sanne, Dolman, Emmy, Lijnzaad, Philip, Custers, Lars, Begthel, Harry, Kerstens, Hindrik H. D., Visser, Lindy L., Rookmaaker, Maarten, Verhaar, Marianne, Tytgat, Godelieve A. M., Kemmeren, Patrick, de Krijger, Ronald R., Al-Saadi, Reem, Pritchard-Jones, Kathy, Kool, Marcel, Rios, Anne C., van den Heuvel-Eibrink, Marry M., Molenaar, Jan J., van Boxtel, Ruben, Holstege, Frank C. P., Clevers, Hans, Drost, Jarno
Publicado 2020

Mesenchymal tumor organoid models recapitulate rhabdomyosarcoma subtypes

por Meister, Michael T, Groot Koerkamp, Marian J A, de Souza, Terezinha, Breunis, Willemijn B, Frazer‐Mendelewska, Ewa, Brok, Mariël, DeMartino, Jeff, Manders, Freek, Calandrini, Camilla, Kerstens, Hinri H D, Janse, Alex, Dolman, M Emmy M, Eising, Selma, Langenberg, Karin P S, van Tuil, Marc, Knops, Rutger R G, van Scheltinga, Sheila Terwisscha, Hiemcke‐Jiwa, Laura S, Flucke, Uta, Merks, Johannes H M, van Noesel, Max M, Tops, Bastiaan B J, Hehir‐Kwa, Jayne Y, Kemmeren, Patrick, Molenaar, Jan J, van de Wetering, Marc, van Boxtel, Ruben, Drost, Jarno, Holstege, Frank C P
Publicado 2022