Partial agonism improves the anti-hyperglycaemic efficacy of an oxyntomodulin-derived GLP-1R/GCGR co-agonist

por Pickford, Phil, Lucey, Maria, Rujan, Roxana-Maria, McGlone, Emma Rose, Bitsi, Stavroula, Ashford, Fiona B., Corrêa, Ivan R., Hodson, David J., Tomas, Alejandra, Deganutti, Giuseppe, Reynolds, Christopher A., Owen, Bryn M., Tan, Tricia M., Minnion, James, Jones, Ben, Bloom, Stephen R.
Publicado 2021

Investigating the Transient Regenerative Potential of Cardiac Muscle Using a Neonatal Pig Partial Apical Resection Model

por Copeland, Katherine M., Brazile, Bryn L., Butler, J. Ryan, Cooley, Jim, Brinkman-Ferguson, Erin, Claude, Andrew, Lin, Sallie, Rais-Rohani, Sammira, Welch, Bradley, McMahan, Sara R., Nguyen, Kytai T., Hong, Yi, Ramaswamy, Sharan, Liu, Zhi-Ping, Bajona, Pietro, Peltz, Matthias, Liao, Jun
Publicado 2022

Screening Libraries to Discover Molecular Design Principles for the Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers Derived from Plant Phenolic...

por Lu, Juncheng, Atochina-Vasserman, Elena N., Maurya, Devendra S., Shalihin, Muhammad Irhash, Zhang, Dapeng, Chenna, Srijay S., Adamson, Jasper, Liu, Matthew, Shah, Habib Ur Rehman, Shah, Honey, Xiao, Qi, Queeley, Bryn, Ona, Nathan A., Reagan, Erin K., Ni, Houping, Sahoo, Dipankar, Peterca, Mihai, Weissman, Drew, Percec, Virgil
Publicado 2023

Chemokine expression predicts T cell-inflammation and improved survival with checkpoint inhibition across solid cancers

por Romero, Joan Miguel, Titmuss, Emma, Wang, Yifan, Vafiadis, James, Pacis, Alain, Jang, Gun Ho, Zhang, Amy, Golesworthy, Bryn, Lenko, Tatiana, Williamson, Laura M., Grünwald, Barbara, O’Kane, Grainne M., Jones, Steven J. M., Marra, Marco. A., Wilson, Julie M., Gallinger, Steven, Laskin, Janessa, Zogopoulos, George
Publicado 2023

1818. A Network Meta-Analysis of Antibiotic Efficacy for the Treatment of Skin and Soft Tissue Infections

por Go-Wheeler, Marianne, Mann, Sarah C, Hean, Sindalisa, Schwartz, Matthew H, Pham, Ann, Judge, Stephen, Kang, Amy Y, Lee, Pamela, Gil, Raul Macias, Launer, Bryn M, Tao, Li, Miller, Elliot I, Flores, Evelyn A, Nguyen, Megan H, Yeh, Maddie, Speciale, Christiana, Miller, Loren G
Publicado 2023

Lessons learned from expanded reproductive carrier screening in self‐reported Ashkenazi, Sephardi, and Mizrahi Jewish patients

por Akler, Gidon, Birch, Ashley H., Schreiber‐Agus, Nicole, Cai, Xiaoqiang, Cai, Guiqing, Shi, Lisong, Yu, Chunli, Larmore, Anastasia M., Mendiratta‐Vij, Geetu, Elkhoury, Lama, Dillon, Mitchell W., Zhu, Jun, Mclellan, Andrew S., Suer, Funda E., Webb, Bryn D., Schadt, Eric E., Kornreich, Ruth, Edelmann, Lisa
Publicado 2019

Self-reported loss of smell without nasal obstruction to identify COVID-19. The multicenter Coranosmia cohort study

por Salmon Ceron, Dominique, Bartier, Sophie, Hautefort, Charlotte, Nguyen, Yann, Nevoux, Jérôme, Hamel, Anne-Laure, Camhi, Yohan, Canouï-Poitrine, Florence, Verillaud, Benjamin, Slama, Dorsaf, Haim-Boukobza, Stephanie, Sourdeau, Elise, Cantin, Delphine, Corré, Alain, Bryn, Agnes, Etienne, Nicolas, Rozenberg, Flore, Layese, Richard, Papon, Jean-François, Bequignon, Emilie
Publicado 2020

Protocol for SYNchronising Exercises, Remedies in GaIt and Cognition at Home (SYNERGIC@Home): feasibility of a home-based double-blind randomised controlled trial to improve gait a...

por McGibbon, Chris, Jarrett, Pam, Handrigan, Grant, Bouchard, Danielle, Tranchant, Carole C, Sexton, Andrew M, Yetman, Linda, Robinson, Bryn, Crapoulet, Stephanie, Chamard-Witkowski, Ludivine, Liu-Ambrose, Teresa, Middleton, Laura Elizabeth, Almeida, Quincy J, Bherer, Louis, Lim, Andrew, Speechley, Mark, Kamkar, Nellie, Montero Odasso, Manuel
Publicado 2022

Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function

por Gruber, Conor N., Calis, Jorg J.A., Buta, Sofija, Evrony, Gilad, Martin, Jerome C., Uhl, Skyler A., Caron, Rachel, Jarchin, Lauren, Dunkin, David, Phelps, Robert, Webb, Bryn D., Saland, Jeffrey M., Merad, Miriam, Orange, Jordan S., Mace, Emily M., Rosenberg, Brad R., Gelb, Bruce D., Bogunovic, Dusan
Publicado 2020

MitoScape: A big-data, machine-learning platform for obtaining mitochondrial DNA from next-generation sequencing data

por Singh, Larry N., Ennis, Brian, Loneragan, Bryn, Tsao, Noah L., Lopez Sanchez, M. Isabel G., Li, Jianping, Acheampong, Patrick, Tran, Oanh, Trounce, Ian A., Zhu, Yuankun, Potluri, Prasanth, Emanuel, Beverly S., Rader, Daniel J., Arany, Zoltan, Damrauer, Scott M., Resnick, Adam C., Anderson, Stewart A., Wallace, Douglas C.
Publicado 2021

Framework From a Multidisciplinary Approach for Transitioning Variants of Unknown Significance From Clinical Genetic Testing in Kidney Disease to a Definitive Classification

por Mirshahi, Uyenlinh L., Bhan, Ahana, Tholen, Lotte E., Fang, Brian, Chen, Guoli, Moore, Bryn, Cook, Adam, Anand, Prince Mohan, Patel, Kashyap, Haas, Mary E., Lotta, Luca A., Igarashi, Peter, de Baaij, Jeroen H.F., Ferrè, Silvia, Hoenderop, Joost G.J., Carey, David J., Chang, Alexander R.
Publicado 2022

Hypoaminoacidemia underpins glucagon-mediated energy expenditure and weight loss

por Hope, David C.D., Hinds, Charlotte E., Lopes, Tatiana, Vincent, Matthew L., Shrewsbury, Jed V., Yu, Arthur T.C., Davies, Iona, Scott, Rebecca, Jones, Ben, Murphy, Kevin G., Minnion, James S., Sardini, Alessandro, Carling, David, Lutz, Thomas A., Bloom, Stephen R., Tan, Tricia M.M., Owen, Bryn M.
Publicado 2022

Long-Term Decrease in Intraocular Pressure in Survivors of Ebola Virus Disease in the Partnership for Research on Vaccines and Infectious Diseases in Liberia (PREVAIL) III Study

por Mudalegundi, Shwetha, Ross, Robin D., Larbelee, Jemma, Amegashie, Fred, Dolo, Robert F., Prakalapakorn, Grace S., Ray, Vincent, Gargu, Catherine, Sosu, Yassah, Sackor, Jennie, Cooper, Precious Z., Wallace, Augustine, Nyain, Ruth, Burkholder, Bryn, Van Ryn, Collin, Davis, Bionca, Fallah, Mosoka P., Reilly, Cavan, Bishop, Rachel J., Eghrari, Allen O.
Publicado 2022

Steroidogenic control of liver metabolism through a nuclear receptor-network

por Milona, Alexandra, Massafra, Vittoria, Vos, Harmjan, Naik, Jyoti, Artigas, Natalia, Paterson, Helen A.B., Bijsmans, Ingrid T.G.W., Willemsen, Ellen C.L., Ramos Pittol, Jose M., Miguel-Aliaga, Irene, Bosma, Piter, Burgering, Boudewijn M.T., Williamson, Catherine, Vernia, Santiago, Dhillo, Waljit S., van Mil, Saskia W.C., Owen, Bryn M.
Publicado 2019

Depression in Individuals Coinfected with HIV and HCV Is Associated with Systematic Differences in the Gut Microbiome and Metabolome

por Taylor, Bryn C., Weldon, Kelly C., Ellis, Ronald J., Franklin, Donald, Groth, Tobin, Gentry, Emily C., Tripathi, Anupriya, McDonald, Daniel, Humphrey, Gregory, Bryant, MacKenzie, Toronczak, Julia, Schwartz, Tara, Oliveira, Michelli F., Heaton, Robert, Grant, Igor, Gianella, Sara, Letendre, Scott, Swafford, Austin, Dorrestein, Pieter C., Knight, Rob
Publicado 2020

Detection of SARS‐CoV‐2 in respiratory samples from cats in the UK associated with human‐to‐cat transmission

por Hosie, Margaret J., Epifano, Ilaria, Herder, Vanessa, Orton, Richard J., Stevenson, Andrew, Johnson, Natasha, MacDonald, Emma, Dunbar, Dawn, McDonald, Michael, Howie, Fiona, Tennant, Bryn, Herrity, Darcy, Da Silva Filipe, Ana, Streicker, Daniel G., Willett, Brian J., Murcia, Pablo R., Jarrett, Ruth F., Robertson, David L., Weir, William
Publicado 2021

Target identification for small-molecule discovery in the FOXO3a tumor-suppressor pathway using a biodiverse peptide library

por Emery, Amy, Hardwick, Bryn S., Crooks, Alex T., Milech, Nadia, Watt, Paul M., Mithra, Chandan, Kumar, Vikrant, Giridharan, Saranya, Sadasivam, Gayathri, Mathivanan, Subashini, Sudhakar, Sneha, Bairy, Sneha, Bharatham, Kavitha, Hurakadli, Manjunath A., Prasad, Thazhe K., Kamariah, Neelagandan, Muellner, Markus, Coelho, Miguel, Torrance, Christopher J., McKenzie, Grahame J., Venkitaraman, Ashok R.
Publicado 2021

Establishing Diagnostic Criteria for Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 3]

por Hilton, Bryn, Gardner, Emma L., Jiang, Zhilin, Tetreault, Lindsay, Wilson, Jamie R. F., Zipser, Carl Moritz, Riew, K. Daniel, Guest, James D., Harrop, James S., Fehlings, Michael G., Rodrigues-Pinto, Ricardo, Rahimi-Movaghar, Vafa, Aarabi, Bizhan, Koljonen, Paul A., Kotter, Mark R. N., Davies, Benjamin M., Kwon, Brian K.
Publicado 2022

Study protocol for a type III hybrid effectiveness-implementation trial to evaluate scaling interoperable clinical decision support for patient-centered chronic pain management in...

por Salloum, Ramzi G., Bilello, Lori, Bian, Jiang, Diiulio, Julie, Paz, Laura Gonzalez, Gurka, Matthew J., Gutierrez, Maria, Hurley, Robert W., Jones, Ross E., Martinez-Wittinghan, Francisco, Marcial, Laura, Masri, Ghania, McDonnell, Cara, Militello, Laura G., Modave, François, Nguyen, Khoa, Rhodes, Bryn, Siler, Kendra, Willis, David, Harle, Christopher A.
Publicado 2022

Virologic Response to Dolutegravir Plus Lamivudine in People With Suppressed Human Immunodeficiency Virus Type 1 and Historical M184V/I: A Systematic Literature Review and Meta-ana...

por Kabra, Madhusudan, Barber, Tristan J, Allavena, Clotilde, Marcelin, Anne-Geneviève, Di Giambenedetto, Simona, Pasquau, Juan, Gianotti, Nicola, Llibre, Josep M, Rial-Crestelo, David, De Miguel-Buckley, Rosa, Blick, Gary, Turner, Matthew, Harrison, Cale, Wynne, Tammy, Verdier, Gustavo, Parry, Chris M, Jones, Bryn, Okoli, Chinyere, Donovan, Cynthia, Priest, Julie, Letang, Emilio
Publicado 2023