Modulating Protein-Protein Interactions of the Mitotic Polo-like Kinases to Target Mutant KRAS

por Narvaez, Ana J., Ber, Suzan, Crooks, Alex, Emery, Amy, Hardwick, Bryn, Guarino Almeida, Estrella, Huggins, David J., Perera, David, Roberts-Thomson, Meredith, Azzarelli, Roberta, Hood, Fiona E., Prior, Ian A., Walker, David W., Boyce, Richard, Boyle, Robert G., Barker, Samuel P., Torrance, Christopher J., McKenzie, Grahame J., Venkitaraman, Ashok R.
Publicado 2017

Clinical, biochemical, and genetic features associated with VARS2‐related mitochondrial disease

por Bruni, Francesco, Di Meo, Ivano, Bellacchio, Emanuele, Webb, Bryn D., McFarland, Robert, Chrzanowska‐Lightowlers, Zofia M.A., He, Langping, Skorupa, Ewa, Moroni, Isabella, Ardissone, Anna, Walczak, Anna, Tyynismaa, Henna, Isohanni, Pirjo, Mandel, Hanna, Prokisch, Holger, Haack, Tobias, Bonnen, Penelope E., Enrico, Bertini, Pronicka, Ewa, Ghezzi, Daniele, Taylor, Robert W., Diodato, Daria
Publicado 2018

Targeting GLP-1 receptor trafficking to improve agonist efficacy

por Jones, Ben, Buenaventura, Teresa, Kanda, Nisha, Chabosseau, Pauline, Owen, Bryn M., Scott, Rebecca, Goldin, Robert, Angkathunyakul, Napat, Corrêa Jr, Ivan R., Bosco, Domenico, Johnson, Paul R., Piemonti, Lorenzo, Marchetti, Piero, Shapiro, A. M. James, Cochran, Blake J., Hanyaloglu, Aylin C., Inoue, Asuka, Tan, Tricia, Rutter, Guy A., Tomas, Alejandra, Bloom, Stephen R.
Publicado 2018

A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2

por Aynaud, Marie-Ming, Hernandez, J. Javier, Barutcu, Seda, Braunschweig, Ulrich, Chan, Kin, Pearson, Joel D., Trcka, Daniel, Prosser, Suzanna L., Kim, Jaeyoun, Barrios-Rodiles, Miriam, Jen, Mark, Song, Siyuan, Shen, Jess, Bruce, Christine, Hazlett, Bryn, Poutanen, Susan, Attisano, Liliana, Bremner, Rod, Blencowe, Benjamin J., Mazzulli, Tony, Han, Hong, Pelletier, Laurence, Wrana, Jeffrey L.
Publicado 2021

Rapid antigen-based and rapid molecular tests for the detection of SARS-CoV-2: a rapid review with network meta-analysis of diagnostic test accuracy studies

por Veroniki, Areti Angeliki, Tricco, Andrea C., Watt, Jennifer, Tsokani, Sofia, Khan, Paul A., Soobiah, Charlene, Negm, Ahmed, Doherty-Kirby, Amanda, Taylor, Paul, Lunny, Carole, McGowan, Jessie, Little, Julian, Mallon, Patrick, Moher, David, Wong, Sabrina, Dinnes, Jacqueline, Takwoingi, Yemisi, Saxinger, Lynora, Chan, Adrienne, Isaranuwatchai, Wanrudee, Lander, Bryn, Meyers, Adrienne, Poliquin, Guillaume, Straus, Sharon E.
Publicado 2023

Effectors Enabling Adaptation to Mitochondrial Complex I Loss in Hürthle Cell Carcinoma

por Gopal, Raj K., Vantaku, Venkata R., Panda, Apekshya, Reimer, Bryn, Rath, Sneha, To, Tsz-Leung, Fisch, Adam S., Cetinbas, Murat, Livneh, Maia, Calcaterra, Michael J., Gigliotti, Benjamin J., Pierce, Kerry A., Clish, Clary B., Dias-Santagata, Dora, Sadow, Peter M., Wirth, Lori J., Daniels, Gilbert H., Sadreyev, Ruslan I., Calvo, Sarah E., Parangi, Sareh, Mootha, Vamsi K.
Publicado 2023

Efficacy and Safety Outcomes of Cataract Surgery in Survivors of Ebola Virus Disease: 12-Month Results From the PREVAIL VII Study

por Eghrari, Allen O., Shantha, Jessica G., Ross, Robin D., Ryn, Collin Van, Crozier, Ian, Hayek, Brent, Gradin, Dan, Roberts, Ben, Prakalapakorn, S. Grace, Amegashie, Fred, Nishant, Kumar, Singh, Gurcharan, Dolo, Robert, Fankhauser, John, Burkholder, Bryn, Pettitt, James, Gross, Robin, Brady, Tyler, Dighero-Kemp, Bonnie, Reilly, Cavan, Hensley, Lisa, Higgs, Elizabeth, Yeh, Steven, Bishop, Rachel J.
Publicado 2021

Measuring outcome differences associated with STEMI screening and diagnostic performance: a multicentred retrospective cohort study protocol

por Yiadom, Maame Yaa A B, Mumma, Bryn E, Baugh, Christopher W, Patterson, Brian W, Mills, Angela M, Salazar, Gilberto, Tanski, Mary, Jenkins, Cathy A, Vogus, Timothy J, Miller, Karen F, Jackson, Brittney E, Lehmann, Christoph U, Dorner, Stephen C, West, Jennifer L, Wang, Thomas J, Collins, Sean P, Dittus, Robert S, Bernard, Gordon R, Storrow, Alan B, Liu, Dandan
Publicado 2018

CTCF is essential for proper mitotic spindle structure and anaphase segregation

por Chiu, Katherine, Berrada, Yasmin, Eskndir, Nebiyat, Song, Dasol, Fong, Claire, Naughton, Sarah, Chen, Tina, Moy, Savanna, Gyurmey, Sarah, James, Liam, Ezeiruaku, Chimere, Capistran, Caroline, Lowey, Daniel, Diwanji, Vedang, Peterson, Samantha, Parakh, Harshini, Burgess, Ayanna R., Probert, Cassandra, Zhu, Annie, Anderson, Bryn, Levi, Nehora, Gerlitz, Gabi, Packard, Mary C., Dorfman, Katherine A., Bahiru, Michael Seifu, Stephens, Andrew D.
Publicado 2023

Clinical and clinicopathological features and outcomes of cats with suspected dietary induced pancytopenia

por Glanemann, Barbara, Humm, Karen, Abreu, Mariana, Aspinall, Sophie, Buckeridge, David, Carveth, Hope, Darcy, Hannah, Florey, Jessica, Frowde, Polly, Gajanayake, Isuru, Green, Kate, Holmes, Emma, Hrovat, Alenka, Jasensky, Anne‐Katherine, Jones, Bryn A, Lantzaki, Vasiliki, Lo, Eve JY, MacDonald, Kirsty, O'Brien, Kevin, Suárez‐Bonnet, Alejandro, Van den Steen, Nele, Szladovits, Balazs, Willems, Annelies, Wilson, Helen
Publicado 2023

SMPDL3b modulates insulin receptor signaling in diabetic kidney disease

por Mitrofanova, A., Mallela, S. K., Ducasa, G. M., Yoo, T. H., Rosenfeld-Gur, E., Zelnik, I. D., Molina, J., Varona Santos, J., Ge, M., Sloan, A., Kim, J. J., Pedigo, C., Bryn, J., Volosenco, I., Faul, C., Zeidan, Y. H., Garcia Hernandez, C., Mendez, A. J., Leibiger, I., Burke, G. W., Futerman, A. H., Barisoni, L., Ishimoto, Y., Inagi, R., Merscher, S., Fornoni, A.
Publicado 2019

Characterization of Ebola Virus–Associated Eye Disease

por Eghrari, Allen O., Bishop, Rachel J., Ross, Robin D., Davis, Bionca, Larbelee, Jemma, Amegashie, Fred, Dolo, Robert F., Prakalapakorn, S. Grace, Gaisie, Catherine, Gargu, Catherine, Sosu, Yassah, Sackor, Jennie, Cooper, Precious Z., Wallace, Augustine, Nyain, Ruth, Gray, Maima, Kamara, Famatta, Burkholder, Bryn, Brady, Christopher J., Ray, Vincent, Tawse, Kirstin L., Yeung, Ian, Neaton, James D., Higgs, Elizabeth S., Lane, H. Clifford, Reilly, Cavan, Sneller, Michael C., Fallah, Mosoka P.
Publicado 2021

Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis

por Mousavy Gharavy, S. Neda, Owen, Bryn M., Millership, Steven J., Chabosseau, Pauline, Pizza, Grazia, Martinez-Sanchez, Aida, Tasoez, Emirhan, Georgiadou, Eleni, Hu, Ming, Fine, Nicholas H. F., Jacobson, David A., Dickerson, Matthew T., Idevall-Hagren, Olof, Montoya, Alex, Kramer, Holger, Mehta, Zenobia, Withers, Dominic J., Ninov, Nikolay, Gadue, Paul J., Cardenas-Diaz, Fabian L., Cruciani-Guglielmacci, Céline, Magnan, Christophe, Ibberson, Mark, Leclerc, Isabelle, Voz, Marianne, Rutter, Guy A.
Publicado 2021

A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death

por Scott, Duncan E., Francis-Newton, Nicola J., Marsh, May E., Coyne, Anthony G., Fischer, Gerhard, Moschetti, Tommaso, Bayly, Andrew R., Sharpe, Timothy D., Haas, Kalina T., Barber, Lorraine, Valenzano, Chiara R., Srinivasan, Rajavel, Huggins, David J., Lee, Miyoung, Emery, Amy, Hardwick, Bryn, Ehebauer, Matthias, Dagostin, Claudio, Esposito, Alessandro, Pellegrini, Luca, Perrior, Trevor, McKenzie, Grahame, Blundell, Tom L., Hyvönen, Marko, Skidmore, John, Venkitaraman, Ashok R., Abell, Chris
Publicado 2021

Intra-Tumoral CD8+ T-Cell Infiltration and PD-L1 Positivity in Homologous Recombination Deficient Pancreatic Ductal Adenocarcinoma

por Golesworthy, Bryn, Wang, Yifan, Tanti, Amanda, Pacis, Alain, Romero, Joan Miguel, Cuggia, Adeline, Domecq, Celine, Bourdel, Guillaume, Denroche, Robert E., Jang, Gun Ho, Grant, Robert C., Borgida, Ayelet, Grünwald, Barbara T., Dodd, Anna, Wilson, Julie M., Bourque, Guillaume, O’Kane, Grainne M., Fischer, Sandra E., Kron, Chelsea Maedler, Fiset, Pierre-Olivier, Omeroglu, Atilla, Foulkes, William D., Gallinger, Steven, Guiot, Marie-Christine, Gao, Zu-Hua, Zogopoulos, George
Publicado 2022

When a Home is Not a Home: MultiDrug-Resistant Organism (MDRO) Colonization and Environmental Contamination in 28 Nursing Homes (NHs)

por McKinnell, James A, Miller, Loren, Singh, Raveena D, Mendez, Job, Franco, Ryan, Gussin, Gabrielle, Chang, Justin, Dutciuc, Tabitha D, Saavedra, Raheeb, Kleinman, Ken, Peterson, Ellena M, Evans, Kaye D, Heim, Lauren, Miner, Aaron, Estevez, Marlene, Custodio, Harold, Yamaguchi, Stacey, Nguyen, Jenny, Varasteh, Alex, Launer, Bryn, Agrawal, Shalini, Tjoa, Thomas, He, Jiayi, Park, Steven, Tam, Steven, Gohil, Shruti K, Stone, Nimalie D, Steinberg, Karl, Montgomery, Jocelyn, Beecham, Nancy, Huang, Susan S
Publicado 2017

DNA methylation dynamics and dysregulation delineated by high-throughput profiling in the mouse

por Zhou, Wanding, Hinoue, Toshinori, Barnes, Bret, Mitchell, Owen, Iqbal, Waleed, Lee, Sol Moe, Foy, Kelly K., Lee, Kwang-Ho, Moyer, Ethan J., VanderArk, Alexandra, Koeman, Julie M., Ding, Wubin, Kalkat, Manpreet, Spix, Nathan J., Eagleson, Bryn, Pospisilik, John Andrew, Szabó, Piroska E., Bartolomei, Marisa S., Vander Schaaf, Nicole A., Kang, Liang, Wiseman, Ashley K., Jones, Peter A., Krawczyk, Connie M., Adams, Marie, Porecha, Rishi, Chen, Brian H., Shen, Hui, Laird, Peter W.
Publicado 2022

A defect in myoblast fusion underlies Carey-Fineman-Ziter syndrome

por Di Gioia, Silvio Alessandro, Connors, Samantha, Matsunami, Norisada, Cannavino, Jessica, Rose, Matthew F., Gilette, Nicole M., Artoni, Pietro, de Macena Sobreira, Nara Lygia, Chan, Wai-Man, Webb, Bryn D., Robson, Caroline D., Cheng, Long, Van Ryzin, Carol, Ramirez-Martinez, Andres, Mohassel, Payam, Leppert, Mark, Scholand, Mary Beth, Grunseich, Christopher, Ferreira, Carlos R., Hartman, Tyler, Hayes, Ian M., Morgan, Tim, Markie, David M., Fagiolini, Michela, Swift, Amy, Chines, Peter S., Speck-Martins, Carlos E., Collins, Francis S., Jabs, Ethylin Wang, Bönnemann, Carsten G., Olson, Eric N., Carey, John C., Robertson, Stephen P., Manoli, Irini, Engle, Elizabeth C.
Publicado 2017

TUBB3 Arg262His causes a recognizable syndrome including CFEOM3, facial palsy, joint contractures, and early-onset peripheral neuropathy

por Whitman, Mary C., Barry, Brenda J., Robson, Caroline D., Facio, Flavia M., Van Ryzin, Carol, Chan, Wai-Man, Lehky, Tanya J., Thurm, Audrey, Zalewski, Christopher, King, Kelly A., Brewer, Carmen, Almpani, Konstantinia, Lee, Janice S., Delaney, Angela, FitzGibbon, Edmond J., Lee, Paul R., Toro, Camilo, Paul, Scott M., Abdul-Rahman, Omar A., Webb, Bryn D., Jabs, Ethylin Wang, Moller, Hans Ulrik, Larsen, Dorte Ancher, Antony, Jayne H., Troedson, Christopher, Ma, Alan, Ragnhild, Glad, Wirgenes, Katrine V., Tham, Emma, Kvarnung, Malin, Maarup, Timothy James, MacKinnon, Sarah, Hunter, David G., Collins, Francis S., Manoli, Irini, Engle, Elizabeth C.
Publicado 2021

Draft Genome Sequence of Nereida sp. Strain MMG025, Isolated from Giant Kelp

por Alker, Amanda T., Hern, Natalie A., Ali, Munira A., Baez, Melissa I., Baswell, Brianna C., Baxter, Bryn I., Blitz, Alyssa, Calimlim, Theresa M., Chevalier, Cierra A., Eguia, Claudia A., Esparza, Tania, Fuller, Alaina E., Gwynn, Caitlin J., Hedin, Allison L., Johnson, Ronnesha A., Kaur, Maninder, Laxina, Rio T., Lee, Kouta, Maguire, Payton N., Martelino, Isabella F., Melendez, Jennifer A., Navarro, Jeannine J., Navarro, Jazmin N., Osborn, James M., Padilla, Mariana R., Peralta, Nicole D., Pureza, John Lawrence R., Rojas, Jesse J., Romo, Taelor R., Sakha, Morsal, Salcedo, Geronimo J., Sims, Kaiden A., Trieu, Thanh Ha, Niesman, Ingrid R., Shikuma, Nicholas J.
Publicado 2022