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81“…The Yersinia pestis pH 6 antigen (PsaA) forms fimbria-like structures and is required for full virulence during bubonic plague. High temperature and low pH regulate PsaA production, and while recent work has uncovered the molecular aspects of temperature control, the mechanisms underlying this unusual regulation by pH are poorly understood. …”
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82por Guiyoule, A, Gerbaud, G, Buchrieser, C, Galimand, M, Rahalison, L, Chanteau, S, Courvalin, P, Carniel, E“…We describe a second Y. pestis strain with high-level resistance to streptomycin, isolated from a human case of bubonic plague in Madagascar. The resistance determinants were carried by a self-transferable plasmid that could conjugate at high frequencies to other Y. pestis isolates. …”
Publicado 2001
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83por Ambrose, Charles T.“…The stability and infectivity of the smallpox virus are reviewed from both a historical (anecdotal) perspective and modern virologic studies. Bubonic plague was the contagious disease that led to quarantines as early as the 14th century in port cities in southern Europe. …”
Publicado 2005
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84“…We concluded that pneumonic plague can be transmitted by intensive handling of the corpse or carcass, presumably through the inhalation of respiratory droplets, and that bubonic plague can be transmitted by blood-to-blood contact with the body fluids of a corpse or carcass. …”
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85“…They cited the fact that Isaac Newton came up with his theory of gravity whilst quarantined during the bubonic plague. Globally, the reaction from many was to inwardly — or publicly — scream.…”
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86por Wei, Furong, Jia, Xiaokai, Wang, Ying, Yang, Yuetao, Wang, Junyun, Gao, Chunhua, Wang, Yong“…Xenopsylla cheopis, also called oriental rat flea, is an ectoparasite as well as disease vector for murine typhus and bubonic plague. In the study, the whole mitochondrial genome of X. cheopis was sequenced and assembled, which is the second report of mitochondrial genome in the family Pulicidae and the sixth mitochondrial genome in the order Siphonaptera (fleas). …”
Publicado 2022
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87por LaRock, Christopher N., Yu, Jing, Horswill, Alexander R., Parsek, Matthew R., Minion, F. Chris“…The etiologic agent of bubonic plague, Yersinia pestis, senses self-produced, secreted chemical signals in a process named quorum sensing. …”
Publicado 2013
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88por Andrianaivoarimanana, Voahangy, Piola, Patrice, Wagner, David M., Rakotomanana, Fanjasoa, Maheriniaina, Viviane, Andrianalimanana, Samuel, Chanteau, Suzanne, Rahalison, Lila, Ratsitorahina, Maherisoa, Rajerison, Minoarisoa“…During 1998–2016, a total of 13,234 suspected cases were recorded, mainly from the central highlands; 27% were confirmed cases, and 17% were presumptive cases. Patients with bubonic plague (median age 13 years) represented 93% of confirmed and presumptive cases, and patients with pneumonic plague (median age 29 years) represented 7%. …”
Publicado 2019
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89“…Whereas Saint Sebastian is associated with plagues only symbolically, Catholic tradition considers Saint Roch to have had real contact with the bubonic plague. Indeed, during his pilgrimage to Rome, Saint Roch helped people suffering from the plague and was, subsequently, himself infected. …”
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90por Fulloon, J. D.“…The first outbreak of the bubonic plague in Norwich was in 1349 when Julian was only six years old and continued for another twenty-one years of sporadic outbreaks in East Anglia. …”
Publicado 2021
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91“…There are three main clinical forms: bubonic plague, septicemic plague, and pulmonary plague. …”
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92“…V. vulnificus is as lethal early diagnosis as Ebola and bubonic plague, so timely treatment is imperative. Sepsis caused by V. vulnificus infection mainly exists in the United States and is rarely reported in Southeast Asia. …”
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93“…Zoonotic diseases are like a sneaky game of “tag” between animals and humans, where the stakes are high and the consequences can be deadly. From the bubonic plague to COVID-19, zoonotic diseases have affected humanity for centuries, reminding us of our interconnectedness with the animal kingdom and the importance of taking proactive measures to prevent their spread. …”
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94por Linte, Guillaume“…Syphilis, although less deadly than other endemic or epidemic diseases such as yellow fever, sleeping sickness and bubonic plague, was one of the most widespread infections in France’s sub-Saharan colonies. …”
Publicado 2023
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95“…Yersinia pestis is the causative agent of bubonic plague, a deadly flea-borne disease responsible for three historic pandemics. …”
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96por Sebbane, Florent, Jarrett, Clayton, Gardner, Donald, Long, Daniel, Hinnebusch, B. Joseph“…Bacteriology and histology analyses revealed that a Ybt-negative strain caused only primary septicemic plague and atypical bubonic plague instead of the typical bubonic form of disease. …”
Publicado 2010
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97“…While this modification is unnecessary to cause pneumonic plague, the substitution is instead needed to efficiently induce the invasive infection associated with bubonic plague. These findings indicate that Y. pestis was capable of causing pneumonic plague before it evolved to optimally cause invasive infections in mammals.…”
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98por Rasmussen, Simon, Allentoft, Morten Erik, Nielsen, Kasper, Orlando, Ludovic, Sikora, Martin, Sjögren, Karl-Göran, Pedersen, Anders Gorm, Schubert, Mikkel, Van Dam, Alex, Kapel, Christian Moliin Outzen, Nielsen, Henrik Bjørn, Brunak, Søren, Avetisyan, Pavel, Epimakhov, Andrey, Khalyapin, Mikhail Viktorovich, Gnuni, Artak, Kriiska, Aivar, Lasak, Irena, Metspalu, Mait, Moiseyev, Vyacheslav, Gromov, Andrei, Pokutta, Dalia, Saag, Lehti, Varul, Liivi, Yepiskoposyan, Levon, Sicheritz-Pontén, Thomas, Foley, Robert A., Lahr, Marta Mirazón, Nielsen, Rasmus, Kristiansen, Kristian, Willerslev, Eske“…We also identify a temporal sequence of genetic changes that lead to increased virulence and the emergence of the bubonic plague. Our results show that plague infection was endemic in the human populations of Eurasia at least 3,000 years before any historical recordings of pandemics.…”
Publicado 2015
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99“…Type III secretion system is a key bacterial symbiosis and pathogenicity mechanism responsible for a variety of infectious diseases, ranging from food-borne illnesses to the bubonic plague. In many Gram-negative bacteria, the type III secretion system transports effector proteins into host cells, converting resources to bacterial advantage. …”
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100por Lemaître, Nadine, Liang, Xiaofei, Najeeb, Javaria, Lee, Chul-Jin, Titecat, Marie, Leteurtre, Emmanuelle, Simonet, Michel, Toone, Eric J., Zhou, Pei, Sebbane, Florent“…Furthermore, LPC-069 is curative in a murine model of one of the most severe human diseases, bubonic plague, which is caused by the Gram-negative bacterium Yersinia pestis. …”
Publicado 2017
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