Comprehensive targeting of resistance to inhibition of RTK signaling pathways by using glucocorticoids

por Gong, Ke, Guo, Gao, Beckley, Nicole A., Yang, Xiaoyao, Zhang, Yue, Gerber, David E., Minna, John D., Burma, Sandeep, Zhao, Dawen, Akbay, Esra A., Habib, Amyn A.
Publicado 2021

Specificity of end resection pathways for double-strand break regions containing ribonucleotides and base lesions

por Daley, James M., Tomimatsu, Nozomi, Hooks, Grace, Wang, Weibin, Miller, Adam S., Xue, Xiaoyu, Nguyen, Kevin A., Kaur, Hardeep, Williamson, Elizabeth, Mukherjee, Bipasha, Hromas, Robert, Burma, Sandeep, Sung, Patrick
Publicado 2020

A dynamic role for dopamine receptors in the control of mammalian spinal networks

por Sharples, Simon A., Burma, Nicole E., Borowska-Fielding, Joanna, Kwok, Charlie H. T., Eaton, Shane E. A., Baker, Glen B., Jean-Xavier, Celine, Zhang, Ying, Trang, Tuan, Whelan, Patrick J.
Publicado 2020

Enhanced dependency of KRAS‐mutant colorectal cancer cells on RAD51‐dependent homologous recombination repair identified from genetic interactions in Saccharomyces cerevisiae

por Kalimutho, Murugan, Bain, Amanda L., Mukherjee, Bipasha, Nag, Purba, Nanayakkara, Devathri M., Harten, Sarah K., Harris, Janelle L., Subramanian, Goutham N., Sinha, Debottam, Shirasawa, Senji, Srihari, Sriganesh, Burma, Sandeep, Khanna, Kum Kum
Publicado 2017

Primary resistance to EGFR inhibition in glioblastoma is mediated by a TNF-JNK-Axl-ERK signaling axis

por Guo, Gao, Gong, Ke, Ali, Sonia, Ali, Neha, Shallwani, Shahzad, Hatanpaa, Kimmo J., Pan, Edward, Mickey, Bruce, Burma, Sandeep, Wang, David H., Kesari, Santosh, Sarkaria, Jann N, Zhao, Dawen, Habib, Amyn A.
Publicado 2017

Endonuclease EEPD1 Is a Gatekeeper for Repair of Stressed Replication Forks

por Kim, Hyun-Suk, Nickoloff, Jac A., Wu, Yuehan, Williamson, Elizabeth A., Sidhu, Gurjit Singh, Reinert, Brian L., Jaiswal, Aruna S., Srinivasan, Gayathri, Patel, Bhavita, Kong, Kimi, Burma, Sandeep, Lee, Suk-Hee, Hromas, Robert A.
Publicado 2017

Tumor-selective use of DNA base excision repair inhibition in pancreatic cancer using the NQO1 bioactivatable drug, β-lapachone

por Chakrabarti, Gaurab, Silvers, Molly A., Ilcheva, Mariya, Liu, Yuliang, Moore, Zachary R., Luo, Xiuquan, Gao, Jinming, Anderson, Glenda, Liu, Lili, Sarode, Venetia, Gerber, David E., Burma, Sandeep, DeBerardinis, Ralph J., Gerson, Stanton L., Boothman, David A.
Publicado 2015

Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone

por Chakrabarti, Gaurab, Moore, Zachary R., Luo, Xiuquan, Ilcheva, Mariya, Ali, Aktar, Padanad, Mahesh, Zhou, Yunyun, Xie, Yang, Burma, Sandeep, Scaglioni, Pier P., Cantley, Lewis C., DeBerardinis, Ralph J., Kimmelman, Alec C., Lyssiotis, Costas A., Boothman, David A.
Publicado 2015

DNA double-strand breaks cooperate with loss of Ink4 and Arf tumor suppressors to generate glioblastomas with frequent Met amplification

por Camacho, Cristel V., Todorova, Pavlina K., Gillam, Molly C., Tomimatsu, Nozomi, del Alcazar, Carlos R Gil, Ilcheva, Mariya, Mukherjee, Bipasha, McEllin, Brian, Vemireddy, Vamsidhara, Hatanpaa, Kimmo, Story, Michael D., Habib, Amyn A., Murty, Vundavalli V., Bachoo, Robert, Burma, Sandeep
Publicado 2014

EEPD1 promotes repair of oxidatively-stressed replication forks

por Jaiswal, Aruna S, Kim, Hyun-Suk, Schärer, Orlando D, Sharma, Neelam, Williamson, Elizabeth A, Srinivasan, Gayathri, Phillips, Linda, Kong, Kimi, Arya, Shailee, Misra, Anurag, Dutta, Arijit, Gupta, Yogesh, Walter, Christi A, Burma, Sandeep, Narayan, Satya, Sung, Patrick, Nickoloff, Jac A, Hromas, Robert
Publicado 2023

Targeting radioresistance and replication fork stability in prostate cancer

por Li, Xiangyi, Baek, GuemHee, Carreira, Suzanne, Yuan, Wei, Ma, Shihong, Hofstad, Mia, Lee, Sora, Gao, Yunpeng, Bertan, Claudia, Fenor de la Maza, Maria de los Dolores, Alluri, Prasanna G., Burma, Sandeep, Chen, Benjamin P.C., Raj, Ganesh V., de Bono, Johann, Pommier, Yves, Mani, Ram S.
Publicado 2022

Microglial pannexin-1 channel activation is a spinal determinant of joint pain

por Mousseau, Michael, Burma, Nicole E., Lee, Kwan Yeop, Leduc-Pessah, Heather, Kwok, Charlie H. T., Reid, Allison R., O’Brien, Melissa, Sagalajev, Boriss, Stratton, Jo Anne, Patrick, Natalya, Stemkowski, Patrick L., Biernaskie, Jeff, Zamponi, Gerald W., Salo, Paul, McDougall, Jason J., Prescott, Steven A., Matyas, John R., Trang, Tuan
Publicado 2018

Transfer function analysis of dynamic cerebral autoregulation: A CARNet white paper 2022 update

por Panerai, Ronney B, Brassard, Patrice, Burma, Joel S, Castro, Pedro, Claassen, Jurgen AHR, van Lieshout, Johannes J, Liu, Jia, Lucas, Samuel JE, Minhas, Jatinder S, Mitsis, Georgios D, Nogueira, Ricardo C, Ogoh, Shigehiko, Payne, Stephen J, Rickards, Caroline A, Robertson, Andrew D, Rodrigues, Gabriel D, Smirl, Jonathan D, Simpson, David M
Publicado 2022

DNA binding and RAD51 engagement by the BRCA2 C-terminus orchestrate DNA repair and replication fork preservation

por Kwon, Youngho, Rösner, Heike, Zhao, Weixing, Selemenakis, Platon, He, Zhuoling, Kawale, Ajinkya S., Katz, Jeffrey N., Rogers, Cody M., Neal, Francisco E., Badamchi Shabestari, Aida, Petrosius, Valdemaras, Singh, Akhilesh K., Joel, Marina Z., Lu, Lucy, Holloway, Stephen P., Burma, Sandeep, Mukherjee, Bipasha, Hromas, Robert, Mazin, Alexander, Wiese, Claudia, Sørensen, Claus S., Sung, Patrick
Publicado 2023

Selective Vulnerability of Senescent Glioblastoma Cells to BCL-XL Inhibition

por Rahman, Masum, Olson, Ian, Mansour, Moustafa, Carlstrom, Lucas P., Sutiwisesak, Rujapope, Saber, Rehan, Rajani, Karishma, Warrington, Arthur E., Howard, Adam, Schroeder, Mark, Chen, Sisi, Decker, Paul A., Sananikone, Eliot F., Zhu, Yi, Tchkonia, Tamar, Parney, Ian F., Burma, Sandeep, Brown, Desmond, Rodriguez, Moses, Sarkaria, Jann N., Kirkland, James L., Burns, Terry C.
Publicado 2022

An untapped window of opportunity for glioma: targeting therapy-induced senescence prior to recurrence

por Riviere-Cazaux, Cecile, Carlstrom, Lucas P., Neth, Bryan J., Olson, Ian E., Rajani, Karishma, Rahman, Masum, Ikram, Samar, Mansour, Moustafa A., Mukherjee, Bipasha, Warrington, Arthur E., Short, Susan C., von Zglinicki, Thomas, Brown, Desmond A., Burma, Sandeep, Tchkonia, Tamar, Schafer, Marissa J., Baker, Darren J., Kizilbash, Sani H., Kirkland, James L., Burns, Terry C.
Publicado 2023

EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair

por Wu, Yuehan, Lee, Suk-Hee, Williamson, Elizabeth A., Reinert, Brian L., Cho, Ju Hwan, Xia, Fen, Jaiswal, Aruna Shanker, Srinivasan, Gayathri, Patel, Bhavita, Brantley, Alexis, Zhou, Daohong, Shao, Lijian, Pathak, Rupak, Hauer-Jensen, Martin, Singh, Sudha, Kong, Kimi, Wu, Xaiohua, Kim, Hyun-Suk, Beissbarth, Timothy, Gaedcke, Jochen, Burma, Sandeep, Nickoloff, Jac A., Hromas, Robert A.
Publicado 2015

BRD4 Promotes DNA Repair and Mediates the Formation of TMPRSS2-ERG Gene Rearrangements in Prostate Cancer

por Li, Xiangyi, Baek, GuemHee, Ramanand, Susmita G., Sharp, Adam, Gao, Yunpeng, Yuan, Wei, Welti, Jon, Rodrigues, Daniel N., Dolling, David, Figueiredo, Ines, Sumanasuriya, Semini, Crespo, Mateus, Aslam, Adam, Li, Rui, Yin, Yi, Mukherjee, Bipasha, Kanchwala, Mohammed, Hughes, Ashley M., Halsey, Wendy S., Chiang, Cheng-Ming, Xing, Chao, Raj, Ganesh V., Burma, Sandeep, de Bono, Johann, Mani, Ram S.
Publicado 2018

Therapy-Induced Senescence: Opportunities to Improve Anticancer Therapy

por Prasanna, Pataje G, Citrin, Deborah E, Hildesheim, Jeffrey, Ahmed, Mansoor M, Venkatachalam, Sundar, Riscuta, Gabriela, Xi, Dan, Zheng, Guangrong, van Deursen, Jan, Goronzy, Jorg, Kron, Stephen J, Anscher, Mitchell S, Sharpless, Norman E, Campisi, Judith, Brown, Stephen L, Niedernhofer, Laura J, O’Loghlen, Ana, Georgakilas, Alexandros G, Paris, Francois, Gius, David, Gewirtz, David A, Schmitt, Clemens A, Abazeed, Mohamed E, Kirkland, James L, Richmond, Ann, Romesser, Paul B, Lowe, Scott W, Gil, Jesus, Mendonca, Marc S, Burma, Sandeep, Zhou, Daohong, Coleman, C Norman
Publicado 2021