Mostrando 221 - 240 Resultados de 1,554 Para Buscar '"CBE"', tiempo de consulta: 0.11s Limitar resultados
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    “…We characterized the transcriptomic profiles of cells from the substantia nigra (SN) of mice with co-injection with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and selective inhibitor of GCase activity (conduritol-β-epoxide, (CBE)) to mimic PD bearing GCase dysfunction (MPTP+CBE), mice treated with MPTP, mice treated with CBE and control mice treated with injection of sodium chloride (NaCl) (vehicle). …”
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  4. 224
    por Gouvea, Julia S., Simon, Matt R.
    Publicado 2018
    “…Tanner recently proposed that many student difficulties in biology stem from underlying cognitive frameworks called cognitive construals (CBE—Life Sciences Education, 11[3], 209–215 [2012]; CBE—Life Sciences Education, 14[1], ar8 [2015]). …”
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    “…The resulting base editors were characterized with multiple genomic sites and were found to have distinct editing features to the N-terminal SaCas9 CBE (Sa-CBE-N). Among them, Sa-CBE-693, in which a cytosine deaminase was inserted between amino acids 693 and 694, showed an increased editing efficiency and a significantly expanded editing window ranging from bases 2-18. …”
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    “…This essay describes an online, evidence-based teaching guide published by CBE—Life Sciences Education at http://lse.ascb.org/evidence-based-teaching-guides/peer-instruction. …”
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