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321por Ge, Yunxiang, Zheng, Weimin, Li, Yujia, Dou, Weibei, Ren, Shan, Chen, Zhigang, Wang, Zhiqun“…Finally, the significant features at left Cbe9, Cbe1, and Cbe7b were found to be useful as sensitive biomarkers to differentiate MSA-c from HCs according to the SVM analysis. …”
Publicado 2022
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322por Jenkinson, George P, Houghton, Natasha, van Zalk, Nejra, Waller, Jo, Bello, Fernando, Tzemanaki, Antonia“…Thematic analysis of free-text responses identified the following 7 themes: women perceive that R-CBE has the potential to address limitations in current screening services; R-CBE may facilitate increased user choice and autonomy; ethical motivations for supporting R-CBE development; accuracy (and users’ perceptions of accuracy) is essential; results management with clear communication is a priority for users; device usability is important; and integration with health services is key. …”
Publicado 2023
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323por Mubarik, Sumaira, Malik, Saima Shakil, Yanran, Zhang, Hak, Eelko, Nawsherwan, Wang, Fang, Yu, Chuanhua“…METHODS: In this ecological study applying mixed-effect multilevel regression models, a country-specific dataset was analyzed by combining data from the Global Burden of Disease study 2019 on female age-standardized BC mortality, incidence, and DALYs rates with information on national/regional BCS availability (against no such program or only a pilot program) and BCS type (only self-breast examination (SBE) and/or clinical breast examination (CBE) [SBE/CBE] versus SBE/CBE with mammographic screening availability [MM and/or SBE/CBE] versus SBE/CBE/mammographic with digital mammography and/or ultrasound (US) [DMM/US and/or previous tests] in BRICS-plus countries. …”
Publicado 2023
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326por Qi, Yuhan, Wang, Jiarong, Zhao, Jichun, Huang, Bing, Xiong, Fei, Du, Xiaojiong, Chen, Xiyang, Guo, Qiang, Wang, Tiehao, Yuan, Ding“…However, there is no level I evidence regarding the comparison safety and efficacy between the CSE stent and CBE stent in AIOD to date. Therefore, this study aims to compare the efficacy and safety of CBE stent (BARD®LIFESTREAM™) and CSE stent (GORE® VIABAHN™) in AIOD. …”
Publicado 2022
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327por Sirait, Lady Margaretha Febriany, Hamajima, Nobuyuki, Suzuki, Yunosuke, Wahyuningsih, Endang Sri, Oktavia, Dwi, Widyastuti, Inthaphatha, Souphalak, Nishino, Kimihiro, Yamamoto, Eiko“…Socio-demographic factors, reproductive factors, lifestyle factors, family history, and the results of VIA and CBE were used for analyses. Binary and multivariate logistic regression analyses were performed to identify factors associated with VIA positive or CBE positive. …”
Publicado 2022
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328“…However, rat APOBEC1-derived cytosine base editor (CBE) that converts C•G to T•A at target genes induced DNA off-targets, regardless of single-guide RNA (sgRNA) sequences. …”
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329por Grünewald, Julian, Zhou, Ronghao, Iyer, Sowmya, Lareau, Caleb A., Garcia, Sara P., Aryee, Martin J., Joung, J. Keith“…We also tested CBEs with cytidine deaminases other than APOBEC1 and found that the human APOBEC3A (hA3A)-based CBE induces substantial RNA base edits, whereas an enhanced A3A (eA3A)-CBE(6), human activation-induced cytidine deaminase (hAID)-CBE(7), and the petromyzon marinus cytidine deaminase (pmCDA1)-based CBE Target-AID(4) induce reduced RNA edits. …”
Publicado 2019
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330“…To over this problem using a quick and effective genetic approach, we developed a multiplex genome editing system using a cytosine base editor (CBE). The CBE system achieved simultaneous double, triple, quadruple, and quintuple gene editing with efficiencies of 100, 100, 83, and 75%, respectively, as well as the 100% editing efficiency of single targets in Bacillus subtilis. …”
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336por Garrison, HowardEnlace del recurso
Publicado 2013
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337por Allchin, DouglasEnlace del recurso
Publicado 2013
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339por Elgin, Sarah C. R., Bangera, Gita, Decatur, Sean M., Dolan, Erin L., Guertin, Laura, Newstetter, Wendy C., San Juan, Elvyra F., Smith, Mary A., Weaver, Gabriela C., Wessler, Susan R., Brenner, Kerry A., Labov, Jay B.Enlace del recurso
Publicado 2016
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340por Boone, William J.Enlace del recurso
Publicado 2016
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