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41por Alzahrani, Abdulaziz A., Cao, Lily L., Aldossary, Hayyaf S., Nathanael, Demitris, Fu, Jiarong, Ray, Clare J., Brain, Keith L., Kumar, Prem, Coney, Andrew M., Holmes, Andrew P.“…Carotid body (CB) hyperactivity promotes hypertension in response to chronic intermittent hypoxia (CIH). The plasma concentration of adrenaline is reported to be elevated in CIH and our previous work suggests that adrenaline directly activates the CB. …”
Publicado 2020
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42por Meng, Yanling, Li, Wenyang, Zou, Ying, Yao, Ye, Huang, Hong, Sun, Jianjun, Li, Xiaomeng, Guo, Shu, Zhang, Xilong, Wang, Wei“…Chronic intermittent hypoxia (CIH) is the most important pathophysiological process of OSA. …”
Publicado 2020
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43por Hu, Chaowei, Li, Jing, Du, Yunhui, Li, Juan, Yang, Yunyun, Jia, Yifan, Peng, Lu, Qin, Yanwen, Wei, Yongxiang“…Chronic intermittent hypoxia (CIH) is the primary feature of obstructive sleep apnoea (OSA), a crucial risk factor for cardiovascular diseases. …”
Publicado 2020
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44“…We recently demonstrated that fictive eupnea is irregular following exposure to chronic intermittent hypoxia (CIH). However, it is unknown how CIH impacts fictive gasping. …”
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45por Docio, Inmaculada, Olea, Elena, Prieto-LLoret, Jesus, Gallego-Martin, Teresa, Obeso, Ana, Gomez-Niño, Angela, Rocher, Asuncion“…We hypothesized that the lack of CB hypoxia response in guinea pig would suppress chemo-reflex sensitization and thereby would attenuate or eliminate respiratory, sympathetic and cardiovascular effects of CIH treatment. The main purpose of this study was to assess if guinea pig CB undergoes overactivation by CIH and to correlate CIH effects on CB chemoreceptors with cardiovascular and respiratory responses to hypoxia. …”
Publicado 2018
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46“…Obstructive sleep apnea (OSA) is a highly prevalent respiratory disorder of sleep, and associated with chronic intermittent hypoxia (CIH). Experimental evidence indicates that CIH is a unique physiological state with potentially “adaptive” and “maladaptive” consequences for cardio-respiratory homeostasis. …”
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47“…Obstructive sleep apnea (OSA) is characterized by the repetitive collapse of the upper airway and chronic intermittent hypoxia (CIH) during sleep. It has been reported that CIH can increase the EMG activity of genioglossus in rats, which may be related to the neuromuscular compensation of OSA patients. …”
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48por Wang, Wanyu, Song, Ailing, Zeng, Yiming, Chen, Xiaoyang, Zhang, Yixiang, Shi, Yonghong, Lin, Yihua, Luo, Wen“…METHODS: 32 healthy male C57B6J mice were randomly divided into CIH, ARB, blank and air control groups. CIH lasted for 12 weeks. …”
Publicado 2018
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49por Takahashi, Keiko, Ueda, Seiji, Kobayashi, Takashi, Nishiyama, Akira, Fujisawa, Yoshihide, Sugaya, Takeshi, Shiota, Satomi, Takahashi, Kazuhisa, Gohda, Tomohito, Horikoshi, Satoshi, Suzuki, Yusuke“…We, therefore, examined the effects of CIH on sympathetic nerve activation in non-obese mice to determine whether renal sympathetic nerve denervation (RD) could ameliorate CIH-mediated cardiovascular effects. …”
Publicado 2018
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50por Black, David S., Lam, Chun Nok, Nguyen, Nathalie T., Ihenacho, Ugonna, Figueiredo, Jane C.“…Objective: Complementary and integrative health (CIH) use among Hispanic adults with colorectal cancer (CRC) diagnosis is not well documented. …”
Publicado 2016
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51“…BACKGROUND: Chronic intermittent hypoxia (CIH) is a key feature of obstructive sleep apnea (OSA) syndrome. …”
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52por Nie, Xinshi, Zhou, Ling, Wang, Aidi, Jin, Hongyu, Qin, Zheng, Pang, Jian, Wang, Wei, Kang, Jian“…The rats were divided into four groups: normal control or normoxic (NO) group, CIH group, CIH + normal saline (NS) group, and CIH + prazosin (PZ, α1-adrenergic antagonist) group. …”
Publicado 2017
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53“…This study was done to determine whether a relationship may exist between CIH and obesity, and body energy balance and leptin signaling during CIH. …”
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54“…Facilitators asked panelists how CIH practitioners could contribute and be mobilized. …”
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55por Martins, Fátima O., Sacramento, Joana F., Olea, Elena, Melo, Bernardete F., Prieto-Lloret, Jesus, Obeso, Ana, Rocher, Asuncion, Matafome, Paulo, Monteiro, Emilia C., Conde, Silvia V.“…Two CIH protocols were tested: A mild CIH paradigm (5/6 hypoxic (5% O(2)) cycles/h, 10.5 h/day) during 35 days and a severe CIH paradigm (30 hypoxic (5% O(2)) cycles, 8 h/day) during 15 days. …”
Publicado 2021
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56por Wang, Jin‐Wei, Li, Ai‐Ying, Guo, Qiu‐Hong, Guo, Ya‐jing, Weiss, James W., Ji, En‐Sheng“…This study is aimed to evaluate the role of endothelin‐1(ET‐1) system in coronary injury and cardiac dysfunction in CIH rats. In our study, Sprague–Dawley rats were exposed to CIH (FiO(2) 9% for 1.5 min, repeated every 3 min for 8 h/d, 7 days/week for 3 weeks). …”
Publicado 2017
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57por Lucking, Eric F., O'Connor, Karen M., Strain, Conall R., Fouhy, Fiona, Bastiaanssen, Thomaz F.S., Burns, David P., Golubeva, Anna V., Stanton, Catherine, Clarke, Gerard, Cryan, John F., O'Halloran, Ken D.“…BACKGROUND: Carotid body (peripheral oxygen sensor) sensitisation is pivotal in the development of chronic intermittent hypoxia (CIH)-induced hypertension. We sought to determine if exposure to CIH, modelling human sleep apnoea, adversely affects cardiorespiratory control in guinea-pigs, a species with hypoxia-insensitive carotid bodies. …”
Publicado 2018
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58por Zhang, Kai, Zhao, Linru, Ma, Zuowang, Wang, Weiding, Li, Xiongfeng, Zhang, Yue, Yuan, Meng, Liang, Xue, Li, Guangping“…CIH rats were subjected to CIH 6 h/d for 30 days and treatment rats were administrated doxycycline while they received CIH. …”
Publicado 2018
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59por Zhang, Xiao-Bin, Cheng, Hui-Juan, Yuan, Ya-Ting, Chen, Yan, Chen, Yi-Yuan, Chiu, Kam Yu, Zeng, Hui-Qing“…Chronic intermittent hypoxia (CIH), a hallmark of obstructive sleep apnea (OSA), is associated with various cardiovascular diseases. …”
Publicado 2021
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60por Miao, Shuai, Yang, Yu, Li, Ruiling, Yin, Li, Zhang, Kai, Cheng, Lijun, Xu, Xiaona, Wang, Weiding, Zhao, Zhiqiang, Li, Guangping“…CIH and CIH-A rats were subjected to CIH for 6 h per day for 4 weeks. …”
Publicado 2020
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