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121“…This study explored the expression of BACE1 (β-amyloid precursor protein cleaving enzyme 1) in the rat carotid body and the effect of CIH (cyclic intermittent hypoxia) on the expression of BACE1. …”
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122por Wang, Yue, Jiang, Hong-feng, Liu, Bei-bei, Chen, Lei-lei, Wang, Yue, Liu, Xin-yan, Suo, Min, Wu, Xiao-fan“…Methods: This study involved ApoE(−/−) mice which were fed with a high-fat diet for 12 weeks and grouped into control and CIH group. During the last 8 weeks, mice in the CIH group were housed in cages to deliver CIH (12 h per day, cyclic inspiratory oxygen fraction 5–20.9%, 180 s cycle). …”
Publicado 2021
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123“…Obstructive sleep apnea (OSA), a sleep breathing disorder featured by chronic intermittent hypoxia (CIH), is associate with pulmonary hypertension. …”
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124por Ganesh, Nithya, Sun, Shengnan, Feder, Ann, Galfalvy, Hanga, Yehuda, Rachel, Byma, Lauren, Haghighi, Fatemeh“…BACKGROUND: Complementary and integrative health (CIH) interventions show promise in improving overall wellness and engaging Veterans at risk of suicide. …”
Publicado 2023
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125por Ren, Jie, Jin, Meng, You, Zhen-xi, Luo, Miao, Han, Yin, Li, Guang-cai, Liu, Hui-guo“…PURPOSE: This study was aimed to evaluate the role of CIH in steatohepatitis progression and the regulatory function of melatonin on fatty liver sensitivity to CIH injury, mainly focusing on autophagy signaling. …”
Publicado 2018
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126por Tang, Xiaojun, Li, Shisheng, Yang, Xinming, Tang, Qinglai, Zhang, Ying, Zeng, Shiying, Li, Mengmeng, Jiang, Kang, Guo, Lu, Huang, Peiying“…OBJECTIVE: To screen for obstructive sleep apnea (OSA) biomarkers, isobaric tags for relative and absolute quantitation (iTRAQ)-labeled quantitative proteomics assay was used to identify differentially expressed proteins (DEPs) during chronic intermittent hypoxia (CIH). METHOD: The iTRAQ technique was applied to compare DEPs in the serum of a CIH rat model and control group. …”
Publicado 2021
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127por DeSilva, Malini B., Settgast, Ann, Chrenka, Ella, Kodet, Amy J., Walker, Patricia F.“…We divided patients into three groups based on care received before September 1, 2019: 1) CIH: primary care clinician at HealthPartners Center for International Health, 2) GI: not CIH and seen by gastroenterology within previous 18 months, and 3) primary care (PC): not CIH and not seen by gastroenterology within previous 18 months. …”
Publicado 2022
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128por Mabry, Steve, Wilson, E. Nicole, Bradshaw, Jessica L., Gardner, Jennifer J., Fadeyibi, Oluwadarasimi, Vera, Edward, Osikoya, Oluwatobiloba, Cushen, Spencer C., Karamichos, Dimitrios, Goulopoulou, Styliani, Cunningham, Rebecca L.“…Long-term effects of gestational CIH on social behaviors were only observed in female offspring, wherein CIH induced social disengagement and suppression of circulating corticosterone levels in young adulthood. …”
Publicado 2023
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129“…Elevated BP was reduced after six sessions of EA treatment and remained low 72 hrs after EA in 18 CIH rats, but not in sham-EA (n = 12) and untreated (n = 6) CIH ones. …”
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130“…Obstructive sleep apnea (OSA), characterized by chronic intermittent hypoxia (CIH), is often present in diabetic (DB) patients. …”
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131por Snyder, Brina, Duong, Phong, Tenkorang, Mavis, Wilson, E. Nicole, Cunningham, Rebecca L.“…Most studies of CIH in rats have been conducted in the Sprague Dawley rat strain. …”
Publicado 2018
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132por Pena, Eduardo, Siques, Patricia, Brito, Julio, Arribas, Silvia M., Böger, Rainer, Hannemann, Juliane, León-Velarde, Fabiola, González, M. Carmen, López, M. Rosario, López de Pablo, Ángel Luis“…Therefore, these molecules may be considered new targets in CIH-induced RVH.…”
Publicado 2020
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133por Hao, Shengyu, Zhu, Xiaodan, Liu, Zilong, Wu, Xiaodan, Li, Shanqun, Jiang, Pan, Jiang, Liyan“…METHOD: In the present study, we established an orthotopic mouse model of primary lung cancer and utilized chronic intermittent hypoxia (CIH) exposure to mimic OSA status. RESULTS: We observed that CIH endows lung cancer with greater metastatic potential, evidenced by increased tumor growth, tumor seeding, and upregulated CSC-related gene expression in the lungs. …”
Publicado 2021
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134por Gu, Hong, Ru, Yiwen, Wang, Wei, Cai, Guanhui, Gu, Lanxin, Ye, Junjie, Zhang, Wei-Bing, Wang, Lin“…CONCLUSION: CIH environment inhibits osteogenesis and orexin-A can reverse bone mass loss induced by CIH through OX1R-Nrf2/HIF-1α pathway.…”
Publicado 2022
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135por Haun, Jolie N., Alman, Amy C., Jean-Baptiste, Esther, Melillo, Christine, McMahon-Grenz, Julie, Paykel, Jacquelyn M.“…Traditionally, CIH has been delivered in person. COVID-19 created a need to identify sustainable remote delivery options to assure access to CIH while practicing public health recommendations. …”
Publicado 2022
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136“…On the one hand, chronic IH (CIH) is an important pathologic feature of obstructive sleep apnea (OSA) syndrome (OSAS), and many studies have confirmed that OSA-related CIH (OSA-CIH) has atherogenic effects involving complex and interacting mechanisms. …”
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137“…Chronic intermittent hypoxia (CIH) induces oxidative stress in the brain, causing sleep disorders. …”
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138por Terrizzi, Antonela Romina, Conti, María Inés, Martínez, María Pilar, Fernández-Solari, Javier“…Adult Wistar rats were exposed to CCH or CIH simulating 4200 meters of altitude during 90 days. …”
Publicado 2018
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139por Han, Ling, Kerns, Robert, Skanderson, Melissa, Luther, Stephen, Fodeh, Samah, Goulet, Joseph, Brandt, Cynthia“…Research to identify and address barriers to CIH use among older Veterans is encouraged.…”
Publicado 2020
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140“…We tested effects of Chronic Intermittent Hypoxia (CIH) – a hallmark of OSA – on airway hyperresponsiveness (AHR), in a rat model of chronic allergen-induced inflammation. …”
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