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  1. 361
    “…Chronic Lung Allograft Dysfunction (CLAD) is a life-threatening complication that limits the long-term survival of lung transplantation patients. …”
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    Chronic Lung Allograft Dysfunction Is Associated with Increased Levels of Cell-Free Mitochondrial DNA in Bronchoalveolar Lavage Fluid of Lung Transplant Recipients
  2. 362
    “…Chronic lung allograft dysfunction (CLAD) phenotype determines prognosis and may have therapeutic implications. …”
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    Quantitative Image Analysis at Chronic Lung Allograft Dysfunction Onset Predicts Mortality
  3. 363
    “…Cladribine (CLAD) is a lymphodepleting agent approved for active relapsing multiple sclerosis (MS). …”
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    Pre-Existing Humoral Immunological Memory Is Retained in Patients with Multiple Sclerosis Receiving Cladribine Therapy
  4. 364
    por Bedair, Bahaa, Hachem, Ramsey R.
    Publicado 2021
    “…Outcomes after lung transplantation are limited by chronic lung allograft dysfunction (CLAD). The incidence of CLAD is high, and its clinical course tends to be progressive over time, culminating in graft failure and death. …”
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    Management of chronic rejection after lung transplantation
  5. 365
    “…Chronic liver allograft dysfunction (CLAD) remains the most common cause of patient morbidity and allograft loss in liver transplant patients. …”
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    CXCL4 Contributes to the Pathogenesis of Chronic Liver Allograft Dysfunction
  6. 366
    “…Such biomarkers would improve CLAD prediction and allow differential LT management regarding CLAD risk.…”
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    Early Identification of Chronic Lung Allograft Dysfunction: The Need of Biomarkers
  7. 367
    “…Cladribine tablets (CladT) preferentially reduce B and T lymphocyte levels. …”
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    Integrated Lymphopenia Analysis in Younger and Older Patients With Multiple Sclerosis Treated With Cladribine Tablets
  8. 368
    “…Chronic lung allograft dysfunction (CLAD) is a major cause of allograft loss post-lung transplantation. …”
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    Symptomatic Respiratory Virus Infection and Chronic Lung Allograft Dysfunction
  9. 369
    “…INTRODUCTION: Chronic lung allograft dysfunction (CLAD) can take two forms: bronchiolitis obliterans syndrome (BOS) or restrictive allograft syndrome (RAS). …”
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    Early chest CT abnormalities to predict the subsequent occurrence of chronic lung allograft dysfunction
  10. 370
    por Gregson, Aric L.
    Publicado 2016
    “…Infection is a recognized risk factor for the development of CLAD, and both acute infection and chronic lung allograft colonization with microorganisms increase the risk for CLAD. …”
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    Infectious Triggers of Chronic Lung Allograft Dysfunction
  11. 371
    “…Our evaluation of published studies over the last 20 years summarizes the complex multifactorial immunopathology of CLAD onset and progression. It highlights the phenotype of several key effector immune cells involved in CLAD pathogenesis, as well as the paucity of single cell resolution spatial studies in lung tissue from patients with CLAD.…”
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    Effector immune cells in chronic lung allograft dysfunction: A systematic review
  12. 372
    “…Chronic lung allograft dysfunction (CLAD) remains a major hurdle impairing lung transplant outcome. …”
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    Biomarkers for Chronic Lung Allograft Dysfunction: Ready for Prime Time?
  13. 373
    “…Risk factors of CLAD have been extensively studied, but the association between gram-negative bacteria (GNB) bronchial colonization and the development of CLAD is controversial. …”
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    Impact of gram negative bacteria airway recolonization on the occurrence of chronic lung allograft dysfunction after lung transplantation in a population of cystic fibrosis patients
  14. 374
    “…The objective of this study was to evaluate cognitive impairment and its risk factors in patients with CLAD. METHODS: We recruited non-demented patients with CLAD from our hospital. …”
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    Does cerebral large-artery disease contribute to cognitive impairment?
  15. 375
    “…Significance: Chronic lung allograft dysfunction (CLAD) is the leading cause of death in transplant patients who survive past the first year post-transplant. …”
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    Small airway dilation measured by endoscopic optical coherence tomography correlates with chronic lung allograft dysfunction
  16. 376
    “…BACKGROUND: Chronic lung allograft dysfunction (CLAD) is the leading cause of poor long-term survival after lung transplantation (LT). …”
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    Systems prediction of chronic lung allograft dysfunction: Results and perspectives from the Cohort of Lung Transplantation and Systems prediction of Chronic Lung Allograft Dysfunction cohorts
  17. 377
    “…Cladribine tablets (CladT) is a highly active oral disease-modifying therapy (DMT) for the management of relapsing multiple sclerosis (RMS). …”
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    Expert Narrative Review of the Safety of Cladribine Tablets for the Management of Relapsing Multiple Sclerosis
  18. 378
    “…System performance measures were comparable or superior to those in previous CLAD reports. We demonstrate that an NHP CLAD system can reliably and accurately control in real-time unconsciousness maintained by anesthesia. …”
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    Closed-loop control of anesthetic state in nonhuman primates
  19. 379
    “…METHODS: In this retrospective single-center cohort study of 441 lung transplant recipients, we formally evaluate the association between respiratory infection and chronic lung allograft dysfunction (CLAD). We furthermore hypothesized that bronchoalveolar lavage fluid (BALF) CXCL9 concentrations are augmented during respiratory infections, and that episodes of infection with elevated BALF CXCL9 are associated with greater CLAD risk. …”
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    The Impact of Allograft CXCL9 during Respiratory Infection on the Risk of Chronic Lung Allograft Dysfunction
  20. 380
    “…Chronic lung allograft dysfunction (CLAD) is the leading cause of death in lung transplant recipients. …”
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    JAK-STAT activation contributes to cytotoxic T cell–mediated basal cell death in human chronic lung allograft dysfunction
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