“…Additionally, the mechanism used by the complex to modulate the genes (rpf, gumB, clp and manA) involved in the biofilm formation and stability was also studied. …”
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“…Carijoa riisei (Duchassaing & Michelotti, 1860) isolate CLP2_A03 was collected by scuba at 32 m on the USTS Texas Clipper (27° 53.7827′N, 93° 36.2702′W). …”
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“…An accelerated substitution rate was found in the protein-coding genes, especially clpP. The effective number of codons (EN(C)), parity rule 2 (PR2), and neutrality plots together revealed that the codon usage bias is affected by mutation and selection. …”
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“…A total of 104 genes were annotated including 80 protein-coding genes, 20 tRNA genes, and 4 rRNA genes. Twelve genes (ClpP, ndhB, ycf3, rpl2, rps12, trnA, trnI, trnR, trnG, trnL, and trnV) were multiple-copy genes. …”
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“…Seventeen protein-coding genes (tpF, ndhA, ndhB, petB, petD, rpl16, rpl2, rps16, trnA-UGC, trnG-UCC, trnI-GAU, trnK-UUU, trnL-UAA, trnV-UAC, clpP, rps12, ycf3) contained one or two introns. …”
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“…Among 15 intron-containing genes, clpP and ycf3 contain two introns and the rest have one intron.…”
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“…Inhibiting the activity of SARS-CoV-2 main protease (Mpro), 3C-like protease (3CLP), is able to block the viral replication and proliferation. …”
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“…ShT = 20.39 ± 8.18 s (p = 0.035), ClpT = 50.66 ± 45.04 vs. 63.55 ± 37.15 s (p = 0.662), LigT = 12.82 ± 3.37 vs. 8.02 ± 3.11 min (p = 0.005), and CT = 16.40 ± 4.5 vs. 11.60 ± 2.5 min (p = 0.013), respectively. …”
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“…We also used semiconductor target areas sequencing and Sanger sequencing to detect the mutations in 15 IHH causative genes in 4 KS patients with cleft lip/palate (CLP) and 8 IGD patients (including 5 KS patients, one nIHH patients and two AIHH patients) without CLP. …”
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“…METHODS: Healthy male Sprague-Dawley rats (weighing 230–250 g) under anesthesia and sedation were subjected to cecal ligation and perforation (CLP). After surgical preparation, rats were randomly assigned to eight groups (n = 6 or 8 each group): sham group (Group A: normal saline gavage); sepsis group (Group B: normal saline gavage); Group C (intraperitoneally, dexamethasone 0.5 mg/kg) immediately after CLP surgery; and rhubarb monomer (100 mg/kg in normal saline)-treated groups (Group D: rhein; Group E: emodin; Group F: 3,8-dihydroxy-1-methyl-anthraquinone-2-carboxylic acid; Group G: 1-O-caffeoyl-2-(4-hydroxy-O-cinnamoyl)-D-glucose; and Group H: daucosterol linoleate). …”
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“…PKCδ inhibition significantly reduced TNF-α-mediated hyperpermeability and TEER decrease in vitro in activated HBMVEC and rat brain in vivo 24 h after CLP induced sepsis. TNF-α-treated HBMVEC showed interrupted tight junction expression, whereas continuous expression of tight junction protein was observed in non-treated or PKCδ-i-treated cells. …”
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“…Similarly, LC3-II, and BECN-1 protein levels were significantly increased and peaked at 2 h after CLP (LC3-II: 3.33 ± 0.12 vs. 1.03 ± 0.15, P < 0.05; BECN-1: 1.57 ± 0.26 vs. 1.02 ± 0.11, P < 0.05) in vivo compared with those after sham operation. …”
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“…METHODS: A sepsis mouse model was established by caecal ligation and puncture (CLP), and liver injury was induced by haematoxylin-eosin (H&E) staining. …”
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“…Adult male C57BL/6 mice were subjected to cecal ligation and puncture (CLP). Serum samples were collected on day 1, 3, 5 and 7 to determine the levels of VDBP, 25-hydroxyvitamin D [25(OH)D(3)], 1,25-dihydroxyvitamin D [1,25(OH)(2)D(3)], interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α). …”
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“…In addition, we found evidence of positive selection of the clpP, matK, and rps3 genes in the three branches related to H. ascyron. …”
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“…METHODS: Cecal ligation and puncture (CLP) was performed to establish the sepsis model. 24 h after CLP, the proportion of activated platelets, the level of sCD40L, the expression of tight-junction proteins, the intestinal barrier function and histological damage of septic mice were analyzed. …”
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“…METHODS: Cecal ligation and puncture (CLP) was performed to establish the sepsis model. 24 h after CLP, the proportion of activated platelets, the level of sCD40L, the expression of tight-junction proteins, the intestinal barrier function and histological damage of septic mice were analyzed. …”
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“…We have previously reported on the discovery of a mitochondrial specific unfolded protein response (mtUPR) in mammalian cells, in which the accumulation of unfolded protein within the mitochondrial matrix results in the transcriptional activation of nuclear genes encoding mitochondrial stress proteins such as chaperonin 60, chaperonin 10, mtDnaJ, and ClpP, but not those encoding stress proteins of the endoplasmic reticulum (ER) or the cytosol. …”
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“…Method spikes, which were performed at 20 ng/l, showed mean recoveries within US EPA Contract Laboratory Protocol (CLP) acceptance criteria. System blanks averaged 0.12 ng/l, and recoveries of NIST 1641c diluted to 29.4 ng/l averaged 93.4%. …”
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“…CONCLUSION: This intra oral appliance design achieved desired skeletal changes during maxillary protraction with RED device in dolichofacial CLP patient. Occlusion and facial profile changes was found to be stable in 1-year follow-up.…”
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