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2001por Kusy, Sophie, Ghosn, Eliver E. B., Herzenberg, Leonore A., Contag, Christopher H.“…In bone marrow, these alterations were accompanied by decreases in populations of common lymphoid progenitors (CLP), common myeloid progenitors (CMP) and megakaryocyte-erythrocyte progenitors (MEP). …”
Publicado 2012
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2002“…It also suggests explanations for the increased stability of the final product complex and for its preferential recognition by the ATP-dependent unfoldase ClpX. Although MuA and many other recombinases share a structurally conserved “DDE” catalytic domain, comparisons among the limited set of available complex structures suggest that some conserved features, such as catalysis in trans and target DNA bending, arose through convergent evolution because they are important for function.…”
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2003por Rattmann, Yanna D., de Souza, Lauro Mera, Malquevicz-Paiva, Simone M., Dartora, Nessana, Sassaki, Guilherme Lanzi, Gorin, Philip A. J., Iacomini, Marcello“…We reported that a flavonoid-rich fraction (HE-Bu) obtained from leaves decreased the lethality induced by cecal ligation and puncture (CLP), a clinically relevant model of sepsis. The oral administration of HE-Bu reduced the late mortality rate by 30%, prevented neutrophil accumulation in lungs, decreased TNF-α and IL-1β serum levels, and markedly decreased iNOS and COX-2 protein expression by ileum cells. …”
Publicado 2012
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2004
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2005“…It is particularly interesting that we observed upregulation of Clp and SppA proteases when FtsH was limited in the mutant lacking FtsH2. …”
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2006“…The title compound, [RuCl(2)(η(6)-C(6)H(6))(C(12)H(22)ClP)]·CHCl(3), was prepared by reaction of [RuCl(2)(η(6)-C(6)H(6))](2) with chlorodicyclohexylphosphane in CHCl(3) at 323 K under argon. …”
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2007
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2008“…We discuss here the role of TOX in specifying CLP toward an innate lymphoid cell fate and hypothesize a possible role for TOX in regulating Notch gene targets during innate lymphoid cell development.…”
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2009por Wake, Hidenori, Mori, Shuji, Liu, Keyue, Morioka, Yuta, Teshigawara, Kiyoshi, Sakaguchi, Masakiyo, Kuroda, Kosuke, Gao, Yuan, Takahashi, Hideo, Ohtsuka, Aiji, Yoshino, Tadashi, Morimatsu, Hiroshi, Nishibori, Masahiro“…We show that a plasma protein histidine-rich glycoprotein (HRG) was decreased significantly in septic mice with cecal ligation and puncture (CLP) and supplementary treatment of septic mice with exogenous HRG improved survival, with strong inhibition of tight attachment of neutrophils to pulmonary vasculatures, subsequent immunothrombosis, DIC state, lung inflammation, hypercytokinemia, and activation of vascular endothelial cells (VECs). …”
Publicado 2016
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2010“…We further uncover that GLR-RME gap junctions regulate RME axon specification through activation of the CDK-5 pathway in a calcium-dependent manner, involving a calpain clp-4. Therefore, our study reveals the function of glia-neuron gap junctions in neuronal axon specification and shows that calcium originated from glial cells can regulate neuronal intracellular pathways through gap junctions. …”
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2011por Ma, Shuai, Xu, Qingqing, Deng, Bo, Zheng, Yin, Tian, Hongyan, Wang, Li, Ding, Feng“…CONCLUSIONS: This study showed that selective granulocyte and monocyte adsorption with cellulose acetate beads might ameliorate cecal ligation and puncture (CLP)-induced sepsis and improve survival and organ function.…”
Publicado 2017
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2012“…At least two proteases induced by heat shock, ClpPA and Lon, were responsible for determining the instability of SmcR. …”
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2013por Frawley, Elaine R., Karlinsey, Joyce E., Singhal, Anshika, Libby, Stephen J., Doulias, Paschalis-Thomas, Ischiropoulos, Harry, Fang, Ferric C.“…Newly identified targets include zinc metalloproteins required for DNA replication and repair (DnaG, PriA, and TopA), protein synthesis (AlaS and RpmE), and various metabolic activities (ClpX, GloB, MetE, PepA, and QueC). The cytotoxic actions of free zinc are mitigated by the ZntA and ZitB zinc efflux transporters, which are required for S. …”
Publicado 2018
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2014
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2015por Boullet, Héloise, Bentot, Fayçal, Hequet, Arnaud, Ganem-Elbaz, Carine, Bechara, Chérine, Pacreau, Emeline, Launay, Pierre, Sagan, Sandrine, Jolivalt, Claude, Lacombe, Claire, Moumné, Roba, Karoyan, Philippe“…Moreover, the in vivo data activity obtained in septic mice reveals that the bacterial killing effect allows the control of the infection and increases the survival rate of cecal ligature and puncture (CLP)-treated mice.…”
Publicado 2019
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2016por Darshetkar, Ashwini M., Datar, Mandar N., Tamhankar, Shubhada, Li, Pan, Choudhary, Ritesh Kumar“…The Eriocaulaceae plastome is characterized by the presence of accD, ycf1 and ycf2 genes and presence of introns in clpP and rpoC1 genes which have been lost in the Graminid plastomes. …”
Publicado 2019
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