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2601“…Average daily weight gain, coughing/sneezing index, losses due to morbidity/mortality, and lung scoring data at slaughter by means of CLP (Ceva Lung Program) were recorded for three consecutive fattening cohorts to achieve a powerful number of animals, one half each vaccinated with the IM vaccine and the other half with the ID vaccine (n = 659 in total). …”
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2602por Mishukov, Artem, Odinokova, Irina, Mndlyan, Ekaterina, Kobyakova, Margarita, Abdullaev, Serazhutdin, Zhalimov, Vitaly, Glukhova, Xenia, Galat, Vasiliy, Galat, Yekaterina, Senotov, Anatoly, Fadeev, Roman, Artykov, Artem, Gasparian, Marine E., Solovieva, Marina, Beletsky, Igor, Holmuhamedov, Ekhson“…ONC201, the anticancer drug, targets and activates mitochondrial ATP-dependent caseinolytic peptidase P (ClpP), a serine protease located in the mitochondrial matrix. …”
Publicado 2022
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2603por Wang, Ziyi, Wang, Xuesong, Guo, Zhe, Liao, Haiyan, Chai, Yan, Wang, Ziwen, Wang, Zhong“…In vivo, compound 7460-0250 could improved survival rate and alleviated lung injury of sepsis mice induced by cecum ligation and puncture (CLP), parallel with the activation of the AKT-mTOR pathway. …”
Publicado 2022
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2604por Mao, Yan, Jiang, Feng, Xu, Xue-Jiao, Zhou, Lan-Bo, Jin, Rui, Zhuang, Li-Li, Juan, Chen-Xia, Zhou, Guo-Ping“…Experiments on mice with cecum ligation puncture (CLP) surgery verified the relationships between IGF2BP1, E2F1, and MIF and demonstrated the significance of IGF2BP1 in MIF-associated pyroptosis in vivo. …”
Publicado 2023
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2605“…Several studies demonstrated that overexpression of CLP YKL-40 was associated with asthma. Moreover, it correlated with exacerbation rate, therapy resistance, poor control of symptoms, and, inversely, with FEV(1). …”
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2606“…In addition, four highly divergent regions, i.e., trnC–petN, trnL–rpl32, ndhD–ccsA, and exon 3 of clpP, were identified as potential DNA barcodes. …”
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2607por Mohammed, Afrah E., Aabed, Kawther, Benabdelkamel, Hicham, Shami, Ashwag, Alotaibi, Modhi O., Alanazi, Mona, Alfadda, Assim A., Rahman, Ishrat“…Among the upregulated proteins were Arginine-tRNA ligase, ATP-dependent Clp protease proteolytic, and flavodoxins. In contrast, down-regulated proteins were ATP synthase subunit alpha and quinone, among others, which are known antibacterial targets. …”
Publicado 2023
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2608por Marques, Patricia X, Wand, Handan, Nandy, Melissa, Tan, Chun, Shou, Huizhong, Terplan, Mishka, Mark, Katrina, Brotman, Rebecca M, Wilson, David P, Ravel, Jacques, Hsia, Ru-ching, Bavoil, Patrik M“…This study tests this hypothesis using an ELISA that measures serum IgG antibodies specific for the nine C. trachomatis Pmp subtypes and four immunodominant antigens (MOMP, OmcB, Hsp60, ClpP) in 265 participants of the Chlamydia Adolescent/Young Adult Reproductive Management (CHARM) cohort. …”
Publicado 2022
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2609por Li, Xin-Dong, Lin, Yi-Cen, Yang, Rui-Si, Kang, Xin, Xin, Wei-Gang, Wang, Feng, Zhang, Qi-Lin, Zhang, Wen-Ping, Lin, Lian-Bing“…Among them, the presence of genes such as clpP, pepO, and feoA suggests a possible advantage of AACE3 over other L. chiayiensis in terms of environmental adaptation. …”
Publicado 2023
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2610por Wakeley, Michelle E., Armstead, Brandon E., Gray, Chyna C., Tindal, Elizabeth W., Heffernan, Daithi S., Chung, Chun-Shiang, Ayala, Alfred“…Patients demonstrated increased co-expression of HVEM(+)BTLA(+) on CD3(+) lymphocytes compared to controls, as well as CD3(+)Ki67(-) lymphocytes. Both L-CLP 48hr mice and critically ill patients demonstrated significant increases in TNF-α. …”
Publicado 2023
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2611por Juramurodov, Inom, Makhmudjanov, Dilmurod, Yusupov, Ziyoviddin, Tojibaev, Komiljon“…As well, three highly variable genes (clpP, accD, and atpF) with high Pi values were detected among protein-coding genes. …”
Publicado 2023
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2612por Philipp, Kauffmann, Anja, Quast, Boris, Schminke, Johanna, Kolle, Susanne, Wolfer, Adam, Stepniewski, Philipp, Meyer-Marcotty, Henning, Schliephake“…RESULTS: The prevalence of orofacial clefts for Goettingen in Lower Saxony was 1:890. 231 patients were male and 173 were female. CLP was most common (39.1%) followed by CP (34.7%), CL (14.4%), CLA (9.9%), and facial clefts (2%). …”
Publicado 2023
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2613por Su, He, Ding, Xiaoxia, Liao, Baosheng, Zhang, Danchun, Huang, Juan, Bai, Junqi, Xu, Subing, Zhang, Jing, Xu, Wen, Qiu, Xiaohui, Gong, Lu, Huang, Zhihai“…Interestingly, we found that 31 genes were likely to be under positive selection, including genes encoding ATP protein subunits, photosystem protein subunit, ribosome protein subunits, NAD(P)H dehydrogenase complex subunits, and clpP, petB, rbcL, rpoCl, ycf4, and cemA genes. These genes may function as key roles in the adaption to diverse environment during evolution. …”
Publicado 2023
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2614por Li, Xuexin, Sun, Bowen, Li, Jie, Ye, Wanlin, Li, Mingjuan, Guan, Fasheng, Wu, Songlin, Luo, Xuerong, Feng, Jianguo, Jia, Jing, Liu, Xueru, Li, Tao, Liu, Li“…Methods: Cecal ligation and perforation (CLP) was performed on C57BL/6J mice to induce sepsis. …”
Publicado 2023
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2615por Guo, Jie, Miao, Yuqing, Nie, Fayi, Gao, Fei, Li, Hua, Wang, Yuan, Liu, Qi, Zhang, Tingbin, Yang, Xiaohang, Liu, Li, Fan, Haiming, Wang, Qiang, Qiao, Haifa“…As a result, the Zn-Shik-PEG NPs demonstrated excellent therapeutic efficacies in lipopolysaccharide (LPS) as well as cecal ligation puncture (CLP) induced sepsis model. These findings suggest that Zn-Shik-PEG NPs may have therapeutic potential for the treatment of other ROS-associated and inflammatory diseases. …”
Publicado 2023
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2616por Mascarenhas, Judita, Volkov, Arsen V, Rinn, Cornelia, Schiener, Jens, Guckenberger, Reinhard, Graumann, Peter L“…We also found that the SMC protein is subject to induced proteolysis, most strikingly as cells enter stationary phase, which is partly achieved by ClpX and LonA proteases. Atomic force microscopy revealed the existence of high order rosette-like SMC structures in vitro, which might explain the formation of the SMC centres in vivo. …”
Publicado 2005
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2617“…This work also describes two large conserved inserts in DNA polymerase III (DnaE) and alanyl-tRNA synthetase that are distinctive characteristics of the Chlorobi species and a 3 aa deletion in ClpB chaperone that is mainly found in various Bacteroidales, Flavobacteriales and Flexebacteraceae, but generally not found in the homologs from other organisms. …”
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2618por Yamanaka, Takeshi, Furukawa, Tomoyo, Matsumoto-Mashimo, Chiho, Yamane, Kazuyoshi, Sugimori, Chieko, Nambu, Takayuki, Mori, Naoki, Nishikawa, Hiroyuki, Walker, Clay B, Leung, Kai-Poon, Fukushima, Hisanori“…Expression of several genes which including those for heat shock proteins (DnaJ, DnaK, ClpB, GroEL and GroES) were up-regulated two to four-fold with statistical significance in biofilm-forming strain 17 as compared to the variant strain 17-2. …”
Publicado 2009
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2619por Ow, Dave Siak-Wei, Lim, Denis Yong-Xiang, Morin Nissom, Peter, Camattari, Andrea, Wong, Victor Vai-Tak“…These included genes of the major HSP70 DnaK chaperone family and key proteases belonging to the Clp and Lon protease systems. Other metabolic gene expression trends include: (1) the differential regulation of several energy metabolic genes, (2) down-regulation of the central metabolic TCA cycle and transport genes, and (3) up-regulation of ribosomal genes. …”
Publicado 2010
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2620“…Significant up-regulation of the chaperones ClpB, HslU and GroEL and high-level expression of two protective small heat shock proteins (IbpA and IbpB) were found in cells overexpressing GST-GlcNAc 2-epimerase-5D but not in GST-Neu5Ac aldolase-5R-expressing E. coli. …”
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