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2761por He, Wenju, Xi, Qiang, Cui, Huantian, Zhang, Pingping, Huang, Rui, Wang, Taihuan, Wang, Dongqiang“…In this study, we established a rat model of sepsis-associated lung injury using the cecal ligation and puncture (CLP) method, and investigated the therapeutic effects of LG on lung injury in rats with sepsis. …”
Publicado 2022
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2762“…We established a severe sepsis rat model using cecal ligation and puncture (CLP). The optimal dose of secukinumab was determined by observing the 7-day survival rate of severe sepsis model rats. …”
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2763“…To investigate the protective effect and mechanism of Astragalus polysaccharide (APS) on septic rats, the present project applied APS at concentrations of 400, 600, and 800 mg/kg/d to rats for prophylactic administration for 7 d, and a rat sepsis model was constructed by the cecum ligation and puncture (CLP) method. Forty-eight rats were divided into six groups of eight each. …”
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2764por Gardner, Sharon L, Tarapore, Rohinton S, Allen, Jeffrey, McGovern, Susan L, Zaky, Wafik, Odia, Yazmin, Daghistani, Doured, Diaz, Zuanel, Hall, Matthew D, Khatib, Ziad, Koschmann, Carl, Cantor, Evan, Kurokawa, Ryo, MacDonald, Tobey J, Aguilera, Dolly, Vitanza, Nicholas A, Mueller, Sabine, Kline, Cassie, Lu, Guangrong, Allen, Joshua E, Khatua, Soumen“…BACKGROUND: ONC201, a dopamine receptor D2 (DRD2) antagonist and caseinolytic protease P (ClpP) agonist, has induced durable tumor regressions in adults with recurrent H3 K27M-mutant glioma. …”
Publicado 2022
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2765“…The variable hotspots in the genome included clpP, ycf1, rnK-rps16, rps16-trnQ, atpH-atpI, trnE-trnT, psbM-trnD, ycf3-trnS, and rpl32-trnL, providing valuable molecular markers for species authentication and regions for inferring phylogenetic relationships among them, as well as for evolutionary studies. …”
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2766“…When we compared the predictive values between prenatal US and MRI, there were significant differences in the PPV of OFCs (P < 0.05), NPV of OFCs (P < 0.05), TPR of CLO (P < 0.001), PPV of CLP (P < 0.05), and TPR of CPO (P < 0.05). CONCLUSION: Our results suggest that prenatal US could be effective for diagnosing and ruling out fetal OFCs. …”
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2767por Cao, Ying-Ya, Zhang, Yuan, Gerile, Wuyun, Guo, Yan, Wu, Li-Na, Wu, Li-Li, Song, Kai, Lu, Wei-Hua, Yu, Jian-Bo“…METHODS: Mice with PLK1 overexpression (CAG-PLK1 mice) or PLK1 inhibition (BI2536-treated mice) underwent caecal ligation and puncture (CLP) to establish a sepsis model. The intestinal barrier function, apoptosis in the intestinal epithelium, mitochondrial function and NF-κB signalling activity were evaluated. …”
Publicado 2022
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2768por Wu, Chia-Hua, Guo, Ling, Hao, Dan, Wang, Qian, Ye, Xiang, Ito, Misa, Huang, Bin, Mineo, Chieko, Shaul, Philip W., Li, Xiang-An“…RESULTS AND DISCUSSION: RAI mice were susceptible to cecal ligation and puncture (CLP)-induced sepsis (6.7% survival in SF1CreSR-BIfl/fl mice versus 86.4% in SR-BIfl/fl mice; p = 0.0001). …”
Publicado 2023
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2769por Cesa-Luna, Catherine, Geudens, Niels, Girard, Léa, De Roo, Vic, Maklad, Hassan R., Martins, José C., Höfte, Monica, De Mot, René“…This global assessment of lipopeptide production capacity revealed it to be confined to the Pseudomonas fluorescens lineage, with most strains synthesizing a single type of CLP. Whereas certain lipopeptide families are specific for a taxonomic subgroup, others are found in distant groups. …”
Publicado 2023
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2770por Jagtap, Ashok Babadev, Yadav, Inderjit Singh, Vikal, Yogesh, Praba, Umesh Preethi, Kaur, Navneet, Gill, Adeshpal Singh, Johal, Gurmukh S.“…AP2, MYB, WRKY, PsbP, bZIP, and NAM, heat shock proteins (HSP20, HSP70, and HSP101/ClpB), as well as genes related to photosynthesis (PsaD & PsaN), antioxidation (APX and CAT) and polyamines (Spd and Spm). …”
Publicado 2023
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2771por Zhang, Danchun, Tu, Jiajun, Ding, Xiaoxia, Guan, Wan, Gong, Lu, Qiu, Xiaohui, Huang, Zhihai, Su, He“…Similar number of SSRs and long repeats were found in Bidens, wherein mononucleotide repeats (A/T), forward and palindromic repeats were the most in abundance. Gene loss of clpP and psbD, IR expansion and contraction were detected in these Bidens plants. …”
Publicado 2023
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2772por Sun, Silei, Wang, Daosheng, Dong, Danfeng, Xu, Lili, Xie, Mengqi, Wang, Yihui, Ni, Tongtian, Jiang, Weisong, Zhu, Xiaojuan, Ning, Ning, Sun, Qian, Zhao, Shuyuan, Li, Mengjiao, Chen, Peili, Yu, Meiling, Li, Jian, Chen, Erzhen, Zhao, Bing, Peng, Yibing, Mao, Enqiang“…The intestinal transcriptome in CLP rats illustrated that Enterococcus and Bacteroides had divergent profiles of correlation with differentially expressed genes, indicating distinctly different roles for these bacteria in sepsis. …”
Publicado 2023
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2773por Lu, Lu, Quan, Lingli, Li, Jian, Yuan, Junbin, Nie, Xinmin, Huang, Xueyuan, Dong, Hang, Su, Yanrong, Huang, Yufen, Kou, Qingjie, Liu, Leping, Liu, Haiting, Zhou, Xionghui, Gui, Rong, Gu, Lan“…When sepsis induced by cecal ligation and puncture (CLP) challenged mice was treated, FZ/MER-AgMOF@Bm could not only reduce the levels of pro-inflammatory factors and lung injury, but also help to improve hypothermia caused by septic shock and prolong survival time. …”
Publicado 2023
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2774por Halbedel, Sven, Sperle, Ida, Lachmann, Raskit, Kleta, Sylvia, Fischer, Martin A., Wamp, Sabrina, Holzer, Alexandra, Lüth, Stefanie, Murr, Larissa, Freitag, Christin, Espenhain, Laura, Stephan, Roger, Pietzka, Ariane, Schjørring, Susanne, Bloemberg, Guido, Wenning, Mareike, Al Dahouk, Sascha, Wilking, Hendrik, Flieger, Antje“…Analysis of the Ny9 genome revealed clpY, dgcB, and recQ inactivating mutations, but phenotypic characterization of several virulence-associated traits of a representative Ny9 isolate showed that the outbreak strain had the same pathogenic potential as other serogroup IIa strains. …”
Publicado 2023
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2775“…Next, a sepsis rat model was constructed by cecal ligation and puncture (CLP), and rats received tail vein injection of PEVs to explore the role of PEVs in sepsis. …”
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2776“…All plant SMXL proteins possess a conserved Clp-N domain, P-loop NTPase, and EAR motif. We identified 63 SMXL genes in cotton and classified these into four evolutionary branches. …”
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2777“…It contains 130 genes, including 85 protein-coding genes, 37 tRNA genes, and 8 rRNA genes. The ycf3 and clpP genes have two introns, with the longest intron in the trnK-UUU gene in the LSC region. …”
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2778por Barriuso-Iglesias, Mónica, Schluesener, Daniela, Barreiro, Carlos, Poetsch, Ansgar, Martín, Juan F“…By contrast, L-2.3-butanediol dehydrogenase (ButA), an ATPase with chaperone activity, the ATP-binding subunit (ClpC) of an ATP-dependent protease complex, a 7 TMHs hypothetical protein cg0896, a conserved hypothetical protein cg1556, and the dihydrolipoamide acyltransferase SucB, were clearly up-regulated at pH 6.0. …”
Publicado 2008
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2779por Manyama, Mange, Larson, Jacinda R, Liberton, Denise K, Rolian, Campbell, Smith, Francis J, Kimwaga, Emmanuel, Gilyoma, Japhet, Lukowiak, Kenneth D, Spritz, Richard A, Hallgrimsson, Benedikt“…The isolated cleft lip (CL) and combined cleft lip and palate (CLP) groups did not differ significantly from one another (Procrustes distance = 0.0416, p = 0.50). …”
Publicado 2014
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2780por Yu, Jie, Sun, Zhihong, Liu, Wenjun, Xi, Xiaoxia, Song, Yuqin, Xu, Haiyan, Lv, Qiang, Bao, Qiuhua, Menghe, Bilige, Sun, Tiansong“…Sequences of 10 housekeeping genes (carB, clpX, dnaA, murC, murE, pepN, pepX, pyrG, recA, and rpoB) were obtained for 239 S. thermophilus strains, which were isolated from home-made fermented dairy foods in 18 different regions of Mongolia and China. …”
Publicado 2015
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