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421por Kang, Beom Ryong, Park, Joon Seong, Ryu, Gwang Rok, Jung, Woo-Jin, Choi, Jun-Seok, Shin, Hye-Min“…This study aims to evaluate the effect of chitosan coating on the formation and properties of Bacillus cyclic lipopeptide (CLP)-loaded liposomes. A nanoencapsulation strategy for a chitosan-coated liposomal system using lecithin phospholipids for the entrapment of antibiotic CLP prepared from Bacillus subtilis KB21 was developed. …”
Publicado 2022
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422“…Five equal groups of 25 adult male Swiss-albino mice were randomly divided (n=5): sham (laparotomy without CLP), CLP, vehicle (equivalent amount of DMSO one hour before CLP), and C21 (0.03 mg/kg, one hour before CLP). …”
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423por Zhang, Wenjing, Zhao, Cui, Sun, Liwei, Yang, Xintao, Yang, Linrui, Liang, Ying, Zhang, Xu, Du, Xiaoxia, Chen, Renji, Li, Chunlin“…Cleft lip and palate (CLP) is one of the most common craniofacial malformations. …”
Publicado 2023
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424“…Sepsis was induced by cecal ligation and puncture (CLP) method in Sprague Dawley rats. Rats were randomly assigned into five groups: animals undergoing a sham CLP (sham group); animals undergoing CLP (CLP group); animals undergoing CLP and treated with AS-IV at 2.5 mg/kg bw (low-dose AS-IV [L-AS] group), at 5 mg/kg bw (mid-dose AS-IV [M-AS] group), and at 10 mg/kg bw (high-dose AS-IV [H-AS] group). …”
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425por Restagno, Damien, Venet, Fabienne, Paquet, Christian, Freyburger, Ludovic, Allaouchiche, Bernard, Monneret, Guillaume, Bonnet, Jeanne-Marie, Louzier, Vanessa“…Pseudomonas was detected in all CLP and Sham’s lungs; in spleen and liver only in CLP at 2.10(7) CFU, and in CLP and Sham at 10(8) CFU. …”
Publicado 2016
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426“…In cells deleted for clpX or clpP, or cells expressing protease-defective mutant protein ClpP(S97A), Z-rings appear normal; however, after photobleaching a region of the Z-ring, fluorescence recovers ~70% more slowly in cells without functional ClpXP than in wild type cells. …”
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427por Mathew, Deepa, Barillas-Cerritos, Julia, Nedeljkovic-Kurepa, Ana, Abraham, Mabel, Taylor, Matthew D., Deutschman, Clifford S.“…HYPOTHESIS: Cecal ligation and puncture (CLP) attenuates IRβ, IRS-1 and IRS-2 phosphorylation. …”
Publicado 2023
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428por Bora, Ejder Saylav, Erdoğan, Arife, Alper Erdoğan, Mumin, Yigitturk, Gurkan, Çakır, Adem, Erbaş, Oytun“…Group 1: Normal (non-operative and orally fed control, n=8); Group 2: Sham operated (n=8); Group 3: Cecal ligation and puncture (CLP) (untreated group, n=8); and Group 4: CLP and 100 μg/kg octreotide i.p. …”
Publicado 2022
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429por Li, Hui, Han, Wei, Polosukhin, Vasilly, Yull, Fiona E., Segal, Brahm H., Xie, Can-Mao, Blackwell, Timothy S.“…Mice treated with BMS-345541 after CLP showed reduced neutrophilic alveolitis and lower levels of KC in bronchoalveolar lavage fluid compared to mice treated with CLP+vehicle. …”
Publicado 2013
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430“…One day after the last injection, CLP was performed to produce a low-grade sepsis. …”
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431“…ClpB subunits comprise two AAA+ modules with an interstitial rod-shaped M-domain. …”
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432por Olivares, Adrian O., Nager, Andrew R., Iosefson, Ohad, Sauer, Robert T., Baker, Tania A.“…We demonstrate that ClpA unfolds some protein substrates substantially faster than the single-ring ClpX enzyme, which also degrades substrates in collaboration with ClpP. …”
Publicado 2014
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433“…METHODS: Totally, 12 rats were randomly divided into CLP group or sham-operated (SHAM) group. Cardiac tissues were harvested 18 h after CLP or sham operation. …”
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434por Nguyen, Tuan‐Anh, Gronauer, Thomas F., Nast‐Kolb, Timon, Sieber, Stephan A., Lang, Kathrin“…We combine genetic code expansion, photocrosslinking and proteomics to identify substrates of the mitochondrial (mt) human caseinolytic protease P (hClpP). Site‐specific incorporation of the diazirine‐bearing amino acid DiazK into the inner proteolytic chamber of hClpP, followed by UV‐irradiation of cells, allows to covalently trap substrate proteins of hClpP and to substantiate hClpP's major involvement in maintaining overall mt homeostasis. …”
Publicado 2022
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435por Abraham, Mabel N, Nedeljkovic-Kurepa, Ana, Fernandes, Tiago, Yaipen, Omar, Brewer, Mariana R, Taylor, Matthew D, Deutschman, Clifford“…The effects of CLP on percentages of IL-1β(+) neutrophils, IL-1β(+) monocytes, cDCs, CD4(+) T cells and CD8(+) T cells were similar in xanomeline - treated and untreated post-CLP mice. …”
Publicado 2023
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436por Li, Jungang, Zhao, Chaoqian, Liu, Chun, Wang, Zhenyu, Ling, Zeming, Lin, Bin, Tan, Bizhi, Zhou, Linquan, Chen, Yan, Liu, Delong, Zou, Xuenong, Liu, Wenge“…Co-doped CLP scaffolds possessed excellent degradation properties compared with those of undoped CLP scaffolds. …”
Publicado 2021
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437por Tsao, Cheng-Ming, Li, Kai-Yi, Chen, Shiu-Jen, Ka, Shuk-Man, Liaw, Wen-Jinn, Huang, Hsieh-Chou, Wu, Chin-Chen“…RESULTS: The levosimendan-treated CLP animals had significantly higher arterial pressure and lower biochemical indices of liver and kidney dysfunction compared to the CLP animals (P < 0.05). …”
Publicado 2014
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438por Tsai, Hsin-Jung, Liao, Mei-Hui, Shih, Chih-Chin, Ka, Shuk-Man, Tsao, Cheng-Ming, Wu, Chin-Chen“…Rats were randomized to one of the following five groups: (1) sham-operated group, (2) Ang-(1–7) (1 mg/kg intravenously infused for 1 h) at 3 h and 6 h after sham operation, (3) CLP, (4) Ang-(1–7) at 3 h after CLP, and (5) Ang-(1–7) at 3 h and 6 h after CLP. …”
Publicado 2018
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439por Shen, Nengxing, Zhang, Haojie, Ren, Yongjun, He, Ran, Xu, Jing, Li, Chunyan, Lai, Weimin, Gu, Xiaobin, Xie, Yue, Peng, Xuerong, Yang, Guangyou“…METHODS: In the present study, the S. scabiei chitinase-like protein 5 (SsCLP5) was characterized and recombinant SsCLP5 (rSsCLP5) was evaluated as a candidate vaccine protein for anti-mite protection in rabbits. …”
Publicado 2018
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440por Wang, Chunyan, Yuan, Wenlin, Hu, Anmin, Lin, Juan, Xia, Zhengyuan, Yang, Catherine F., Li, Yalan, Zhang, Zhongjun“…In the present study, sepsis was induced by cecal ligation and puncture (CLP) in male C57BL/6 mice. Dex and yohimbine hydrochloride (YOH), an α2-AR inhibitor, were administered before inducing CLP. …”
Publicado 2020
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