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621por Parisi, Ludovica, Rihs, Silvia, La Scala, Giorgio C., Schnyder, Isabelle, Katsaros, Christos, Degen, Martin“…Hence, cleft lip and palate (CLP) lip-derived fibroblasts could be thought as an intriguing cell source for personalized regenerative therapies in CLP-affected patients. …”
Publicado 2022
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622por Busch, Katharina, Kny, Melanie, Huang, Nora, Klassert, Tilman E., Stock, Magdalena, Hahn, Alexander, Graeger, Sebastian, Todiras, Mihail, Schmidt, Sibylle, Chamling, Bishwas, Willenbrock, Michael, Groß, Stefan, Biedenweg, Doreen, Heuser, Arnd, Scheidereit, Claus, Butter, Christian, Felix, Stephan B., Otto, Oliver, Luft, Friedrich C., Slevogt, Hortense, Fielitz, Jens“…WT CLP) cardiac function and attenuated cardiac (heart weight–tibia length ratio: WT CLP vs. …”
Publicado 2021
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623por Hartwig, Christina, Drechsler, Susanne, Vainshtein, Yevhen, Maneth, Madeline, Schmitt, Theresa, Ehling-Schulz, Monika, Osuchowski, Marcin, Sohn, Kai“…Microbial species compositions were determined by NGS of (cell-free) DNA and confirmed by microbiological cultivation. As a result, CLP induced rapid and early changes of gut microbial communities, with a transition of pathogenic species into the peritoneum and blood detected at 24 h post-CLP. …”
Publicado 2023
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624por Niranjane, P. Priyanka, Kamble, R. H., Diagavane, S. Pallavi, Shrivastav, S. Sunita, Batra, Puneet, Vasudevan, S. D., Patil, Pushkar“…However, literature reports lot of controversy regarding the use of PSIO in patients with CLP. Evaluation of long-term results of PSIO can provide scientific evidence on the efficacy and usefulness of PSIO in CLP patients. …”
Publicado 2014
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625por Zhu, Mei-fei, Xing, Xi, Lei, Shu, Wu, Jian-nong, Wang, Ling-cong, Huang, Li-quan, Jiang, Rong-lin“…We demonstrated here that EA preconditioning at ST36 obviously ameliorated CLP-induced intestinal injury and high permeability and reduced the mortality of CLP-induced sepsis rats. …”
Publicado 2015
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626“…We report that Salmonella enterica increases the specificity of the broadly conserved proteases Lon and ClpSAP by transforming the Lon activator and substrate HspQ into an inhibitor of the N-degron recognin ClpS, the adaptor of the ClpAP protease. …”
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627“…We constructed a rat model of sepsis by cecal ligation and puncture (CLP). The rats were randomly divided into the control group, the sham group, the CLP group and the IL-5 group, with 6 rats in each group. …”
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628“…METHODS: Sepsis was induced by cecal ligation and puncture (CLP) in mice. Bone marrow-derived MSCs from mice were cultured and injected via tail vein on the 8(th) day after CLP. …”
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629por Sun, Junyi, Ding, Xianfei, Liu, Shaohua, Duan, Xiaoguang, Liang, Huoyan, Sun, Tongwen“…METHODS: A total of 60 male adult Sprague-Dawley (SD) rats were separated into three groups: the sham control (SC) group, the sepsis induced by cecal ligation and puncture (CLP) group, and the ADMSC treatment (CLP-ADMSCs) group, in which rats underwent the CLP procedure and then received 1 × 10(6) ADMSCs. …”
Publicado 2020
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630por Jiang, Jihong, Hu, Baoji, Chung, Chun-Shiang, Chen, Yaping, Zhang, Yunhe, Tindal, Elizabeth W., Li, Jinbao, Ayala, Alfred“…METHODS: Male C57BL/6 mice were subjected to Hem (a “priming” insult) followed by CLP or sham-Hem plus sham-CLP (S/S) as controls. …”
Publicado 2020
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631por Becker, Nils, Störmann, Philipp, Janicova, Andrea, Köhler, Kernt, Horst, Klemens, Dunay, Ildiko Rita, Neunaber, Claudia, Marzi, Ingo, Vollrath, Jan Tilmann, Relja, Borna“…METHODS: C57BL/6N mice were divided into three groups, receiving isolated blunt chest trauma (TxT), undergoing TxT followed by cecal ligation and puncture (CLP, TxT + CLP) after 24 h, or sham undergoing analgosedation (n = 18/group). …”
Publicado 2021
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632“…This regulon comprises several protein chaperone genes, including clpC, clpE and clpX, and is controlled by transcriptional repression. …”
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633por Meng, Wei, Paunel-Görgülü, Adnana, Flohé, Sascha, Hoffmann, Almuth, Witte, Ingo, MacKenzie, Colin, Baldus, Stephan E, Windolf, Joachim, Lögters, Tim T“…METHODS: In a prospective controlled double-armed animal trial, polymicrobial sepsis was induced by cecal ligation and puncture (CLP). After CLP, mice were treated with rhDNase or phosphate buffered saline, respectively. …”
Publicado 2012
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634“…METHODS: ILT4(+/+) (WT) and ILT4-knockout (ILT4(−/−)) male BALB/c mice were used for sepsis modeling using cecal ligation puncture (CLP). Flow cytometry was used to measure the levels of ILT4 and major histocompatibility complex class II (MHC-II) on peripheral blood monocytes 24 h after CLP. …”
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635por Eyenga, Pierre, Roussel, Damien, Morel, Jerome, Rey, Benjamin, Romestaing, Caroline, Gueguen-Chaignon, Virginie, Sheu, Shey-Shing, Viale, Jean Paul“…METHODS: We induced sepsis in rats by cecal ligation and perforation (CLP). Six, 24, or 36 h following CLP, we measured liver mitochondrial respiration, cytochrome c oxidase activity, and membrane permeability. …”
Publicado 2018
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636por Zhong, Xiaoli, Xie, Lingli, Yang, Xiaolong, Liang, Fang, Yang, Yanliang, Tong, Jianbin, Zhong, Yanjun, Zhao, Kai, Tang, Yiting, Yuan, Chuang“…METHODS: After CLP, C57BL/6 mice were intraperitoneally or intrathecally injected with saline or ethyl pyruvate using the sham-operated mice as control. …”
Publicado 2020
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637“…Human ghrelin and GH or vehicle (PBS) were administrated subcutaneously at 5 h post CLP. After 20 h of CLP, serum and spleens were harvested. …”
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638por Phuengmaung, Pornpimol, Khiewkamrop, Phuriwat, Makjaroen, Jiradej, Issara-Amphorn, Jiraphorn, Boonmee, Atsadang, Benjaskulluecha, Salisa, Ritprajak, Patcharee, Nita-Lazar, Aleksandra, Palaga, Tanapat, Hirankarn, Nattiya, Leelahavanichkul, Asada“…In LPS tolerance, downregulated NF-κB compared with the control was also demonstrated in Ezh2 null cells. In CLP sepsis mice, those with CLP alone and CLP at 2 days after twice receiving LPS injection, representing sepsis and sepsis after endotoxemia, respectively, symptoms were less severe in Ezh2 null mice, as indicated by survival analysis and other biomarkers. …”
Publicado 2023
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639por Flierl, Michael A, Rittirsch, Daniel, Weckbach, Sebastian, Huber-Lang, Markus, Ipaktchi, Kyros, Ward, Peter A, Stahel, Philip F“…METHODS: Sepsis was induced in adult male Sprague-Dawley rats by cecal ligation and puncture (CLP). Plasma samples were obtained as a function of time (6-48 hrs) after CLP and compared with healthy animals (neg ctrl). …”
Publicado 2011
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640por Kaplan, Jennifer M., Nowell, Marchele, Lahni, Patrick, O’Connor, Michael, Hake, Paul W., Zingarelli, Basilia“…After 3 weeks of feeding, sepsis was induced by cecal ligation and puncture (CLP) and animals were monitored for survival. In a separate experiment, after 3 weeks of feeding mice underwent CLP and were sacrificed at various time-points thereafter. …”
Publicado 2012
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