Mostrando 781 - 800 Resultados de 2,845 Para Buscar '"CLP"', tiempo de consulta: 0.11s Limitar resultados
  1. 781
    “…Whereas, little is known about the affection of melatonin and mitophagy on CLP-induced ALI. METHODS: The in vivo effect of melatonin on OPTN-mediated mitophagy was studied by CLP-induced ALI in a mouse model using C57BL/6 followed by treatment with vehicle and melatonin (30 mg/kg/d, intraperitoneal injection). …”
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    Melatonin Attenuates Sepsis-Induced Acute Lung Injury via Inhibiting Excessive Mitophagy
  2. 782
    “…Inhibition of ERK, not JNK, significantly increased TER and expression of claudin 4 in 2CLP monolayers, and prevented significant differences in claudin 18 expression between 2CLP and sham monolayers. …”
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    Cultured Alveolar Epithelial Cells From Septic Rats Mimic In Vivo Septic Lung
  3. 783
    “…METHODS: Male C57BL/6 mice that underwent severe CLP or sham surgery were intraperitoneally or intravenously administered anti-IL17A antibodies or isotype antibodies. …”
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    Neutralisation of Peritoneal IL-17A Markedly Improves the Prognosis of Severe Septic Mice by Decreasing Neutrophil Infiltration and Proinflammatory Cytokines
  4. 784
    “…We induced polymicrobial sepsis in mice using cecal ligation and puncture (CLP) in the presence or absence of competitive heparanase inhibitors (heparin or nonanticoagulant N-desulfated re-N-acetylated heparin [NAH]). …”
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    Heparanase mediates renal dysfunction during early sepsis in mice
  5. 785
    “…New pro-angiogenic factor YKL-40 belongs to a family of mammalian chitinase-like proteins (CLP) that act as cytokines or growth factors. Human CLP family comprises YKL-40, YKL-39, and SI-CLP. …”
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    Role of tumor associated macrophages in tumor angiogenesis and lymphangiogenesis
  6. 786
    “…The present study aims to evaluate the effects of this combination on a murine model of polymicrobial sepsis induced by cecal ligation and puncture (CLP). Severe sepsis was induced in male ICR mice (n = 7) via the CLP procedure. …”
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    Kaempferol and Chrysin Synergies to Improve Septic Mice Survival
  7. 787
    “…After this period, the CLP was performed. Naïve and Sham groups were performed as non-infected controls. …”
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    Prophylactic Treatment With Simvastatin Modulates the Immune Response and Increases Animal Survival Following Lethal Sepsis Infection
  8. 788
    “…These effects were observed only when IGF-1 was administered within 0–6 hours after CLP. Moreover, cytochrome C and caspase-9 expression levels were increased at 6 hours after CLP in the hippocampus, while TNFR and caspase-8 amounts were not increased until 12 hours after CLP. …”
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    Effects of early administration of insulin-like growth factor-1 on cognitive function in septic encephalopathy
  9. 789
    “…Results: Compared with the CLP group, the administration of DDWs and ML significantly (p < 0.05) prevented the increase of LP, COX-2 and PGE2 levels and liver enzymes. …”
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    Synergistic effects of deuterium depleted water and Mentha longifolia L. essential oils on sepsis-induced liver injuries through regulation of cyclooxygenase-2
  10. 790
    “…CC16 was neutralized by the intratracheal application of an anti-CC16-antibody, either after TxT (early) or following CLP (late). Euthanasia was performed at 6 or 24 h post-CLP. …”
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    Early Local Inhibition of Club Cell Protein 16 Following Chest Trauma Reduces Late Sepsis-Induced Acute Lung Injury
  11. 791
    “…METHODS: A blast SMS text informing local populations of upcoming cleft lip‐palate (CLP) surgical services was distributed to 25% of the subscriber base 1 week prior to arrival of a (CLP) surgical team in Zimbabwe. …”
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    Role of mobile health on patient enrollment for cleft lip‐palate surgery: A comparative study using SMS blast text messaging in zimbabwe
  12. 792
    “…Sepsis was induced using cecal ligation and puncture (CLP). The SS and SA groups received saline or Arg (300 mg/kg body weight) via tail vein 1 h after CLP. …”
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    Intravenous Arginine Administration Benefits CD4(+) T-Cell Homeostasis and Attenuates Liver Inflammation in Mice with Polymicrobial Sepsis
  13. 793
    “…In the current study, we employed the murine cecal ligation and puncture (CLP) model for sepsis to evaluate the effect of post-CLP infusion of apoptotic cells (Allocetra-OTS) on a CLP severe sepsis model. …”
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    Apoptotic cell therapy for cytokine storm associated with acute severe sepsis
  14. 794
    “…Transfection of STAT3 decoy ODNs downregulated pro-inflammatory cytokine/chemokine overproduction in CLP mice. Moreover, STAT3 decoy ODN transfection significantly reduced the increases in tissue mRNAs and proteins of high mobility group box 1 (HMGB1) and strongly suppressed the excessive elevation in serum HMGB1 levels in CLP mice. …”
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    Beneficial effect of STAT3 decoy oligodeoxynucleotide transfection on organ injury and mortality in mice with cecal ligation and puncture-induced sepsis
  15. 795
    “…METHODS: A septic rat model caused by cecal ligation and puncture (CLP) and a postsplenectomy (SPX) CLP rat model were established. …”
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    Effect of Electroacupuncture at Zusanli (ST36) on Sepsis Induced by Cecal Ligation Puncture and Its Relevance to Spleen
  16. 796
    “…An age-dependent metabolome analysis of the wild type and a PaClpP deletion strain verified differences and changes of various metabolites in cultures of the PaClpP mutant and the wild type. …”
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    Simultaneous Ablation of the Catalytic AMPK α-Subunit SNF1 and Mitochondrial Matrix Protease CLPP Results in Pronounced Lifespan Extension
  17. 797
    “…Methods  The effects of P2Y (12) inhibition using clopidogrel treatment and of platelet-specific deletion of the P2Y (12) receptor in mice were examined in two severity grades of cecal ligation and puncture (CLP) leading to mild sepsis or septic shock. Results  Twenty hours after induction of the high grade CLP, clopidogrel- and vehicle-treated mice displayed a similar 30% decrease in mean arterial blood pressure (MAP) characteristic of shock. …”
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    Platelet P2Y (12) Receptor Deletion or Pharmacological Inhibition does not Protect Mice from Sepsis or Septic Shock
  18. 798
    “…However, CLP extract showed a statistically significant difference on M. canis inhibition at 62.21% followed by surfactin with 59.04% at 72 h after treatment. …”
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    Efficacy of cyclic lipopeptides obtained from Bacillus subtilis to inhibit the growth of Microsporum canis isolated from cats
  19. 799
    “…Administration of GDZ824 reduced CLP-induced increases in the number of alveolar neutrophils. …”
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    c-Abl kinase regulates neutrophil extracellular trap formation and lung injury in abdominal sepsis
  20. 800
    “…To induce acute peritonitis in rats, the cecal ligation and perforation (CLP) model was used. Sixty rats were divided into six groups, namely, sham operation, plasma irrigation, CLP, dry cleaning after CLP, saline irrigation after CLP, and plasma-treated saline irrigation after CLP group. …”
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    Irrigation of peritoneal cavity with cold atmospheric plasma treated solution effectively reduces microbial load in rat acute peritonitis model
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