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921por Owusu-Darko, Rodney, Allam, Mushal, Ismail, Arshad, Ferreira, Carlos A. S., de Oliveira, Sílvia D., Buys, Elna M.“…The study identified ClpC, ClpE, and ClpX as the three ATPases putatively involved in protein disaggregation in B. sporothermodurans. …”
Publicado 2020
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922por Han, Xue, Chen, Daili, Liufu, Ning, Ji, Fengtao, Zeng, Qingshi, Yao, Weifeng, Cao, Minghui“…METHODS: The cecal ligation and puncture (CLP) model was created to induce SIMD in rats. Protein levels of MG53 and PPARα, cardiac function, cardiomyocyte injury, myocardial oxidative stress and inflammatory indicators, and cardiomyocyte apoptosis were measured at 18 h after CLP. …”
Publicado 2020
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923por Soria-Bustos, Jorge, Ares, Miguel A., Gómez-Aldapa, Carlos A., González-y-Merchand, Jorge A., Girón, Jorge A., De la Cruz, Miguel A.“…In vivo data strongly suggest that both T6SSs are required for intestinal colonization because single and double mutants in clpV1 and clpV2 genes were defective in gut colonization in mice. …”
Publicado 2020
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924Chronic lead poisoning induced abdominal pain and anemia: a case report and review of the literaturepor Yang, Yuan, Li, Shujun, Wang, Hong, Liu, Morong, Tuo, Biguang, Wu, Huichao, Deng, Shili, Liu, Xuemei“…BACKGROUND: Chronic lead poisoning (CLP) is a rare cause of abdominal pain and is common in young children, in whom the incidence is higher than it is in adults. …”
Publicado 2020
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925por Carpenter, Kelsey C., Zhou, Yesen, Hakenjos, John M., Fry, Christopher D., Nemzek, Jean A.“…Male C57BL/6 mice were housed at 22°C or 30°C after cecal ligation and puncture (CLP) for 10 days. Survival of mice housed at 30°C (78%) after CLP was significantly increased compared with mice housed at 22°C (40%). …”
Publicado 2020
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926por Park, Cho Rong, Paik, Seungwha, Kim, Young Jae, Kim, Jin Kyung, Jeon, Sang Min, Lee, Sang-Hee, Whang, Jake, Cheng, Jinhua, Suh, Joo-Won, Cao, Jin, Shetye, Gauri, Chen, Shao-Nong, McAlpine, James, Pauli, Guido F., Franzblau, Scott, Cho, Sanghyun, Jo, Eun-Kyeong“…This study shows that the rufomycins 4/5/6/7 (Rufomycin 4–7), which targets ClpC1 as a subunit of caseinolytic protein complex ClpC1/ClpP1/ClpP2 of mycobacteria, exhibits a dual effect in host innate defense and in vivo antimicrobial activities against a rough morphotype of Mycobacterium abscessus (Mabs-R), a clinically severe morphotype that causes hyperinflammation. …”
Publicado 2021
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927por Li, Zhenhan, Ludwig, Nadine, Thomas, Katharina, Mersmann, Sina, Lehmann, Martin, Vestweber, Dietmar, Pittet, Jean-Francois, Gomez, Hernando, Kellum, John A., Rossaint, Jan, Zarbock, Alexander“…Furthermore, plasma transfer experiments suggest that the pathogenesis of CLP-induced AKI relies on circulating inflammatory mediators. …”
Publicado 2022
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928por Balion, Zbigniev, Svirskienė, Nataša, Svirskis, Gytis, Inokaitis, Hermanas, Cėpla, Vytautas, Ulčinas, Artūras, Jelinskas, Tadas, Eimont, Romuald, Paužienė, Neringa, Valiokas, Ramūnas, Jekabsone, Aistė“…Our findings indicate that the synthetic CLP-PEG hydrogels ensure more tissue-like microglial morphology, motility, and function than the crosslinked collagen substrates.…”
Publicado 2022
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929“…The STAT3 activation (increased pSTAT3) and increased angiotensin-converting enzyme 2 (ACE2) expressions were observed in CLP mice. The low responsive expressions of pSTAT3 and ACE2 to septic inflammation in CLP AKI mice were associated with BBL. …”
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930por Senousy, Shaymaa Ramzy, El-Daly, Mahmoud, Ibrahim, Ahmed R. N., Khalifa, Mohamed Montaser A., Ahmed, Al-Shaimaa F.“…The aim of this study was to compare the effects of infliximab (IFX) and celecoxib (CLX) on septic rats that went through a cecal ligation and puncture (CLP) surgery to induce sepsis. This study included four groups: sham, CLP (untreated), and CLP-treated with CLX or IFX. …”
Publicado 2022
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931por Herrera-Atoche, José Rubén, Huerta-García, Nieves Aime, Escoffié-Ramírez, Mauricio, Aguilar-Pérez, Fernando Javier, Aguilar-Ayala, Fernando Javier, Lizarraga-Colomé, Eduardo Andrés, Colomé-Ruiz, Gabriel Eduardo, Zúñiga-Herrera, Iván Daniel“…The case group consisted of 192 non-syndromic patients with complete CLP, while the control group included 411 patients. …”
Publicado 2022
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932“…After GA injection, the number of total cells, neutrophils, and macrophages in the CLP rats was reduced and the levels of TNF-α, IL-1β, HMGB1, TLR4, p-38 MAPK, and ERK1/2 in the CLP rat were also repressed. …”
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933por Shaye, David A., Nakarmi, Kiran Kishor, Shakya, Pramila, Pradhan, Leeza, Bhattarai, Kabita, Rayamajhi, Badri, Joshi, Hemanta Dhoj, Yuen, Courtney M., Shrestha, Kailash Khaki, Rai, Shankar Man“…BACKGROUND: In Nepal's remote regions, challenging topography prevents patients with cleft lip and palate (CLP) from seeking care. OBJECTIVE: To measure the effect of a mobile surgical scout program on CLP surgical care in remote regions of Nepal. …”
Publicado 2022
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934“…RESULTS: Chemogenetic activation of the HPC‐PFC pathway enhanced cognitive dysfunction in CLP‐induced septic mice. Glutamate receptors mediated the effects of HPC‐PFC pathway activation in CLP mice. …”
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935por Mehanna, Joe, Massaad, Abir, Assi, Ayman, Rassi, Joe, Atallah, Alexis, Ghanem, Ismat“…Introduction: The calcaneal lengthening procedure (CLP) is a well-known surgical technique used for the correction of symptomatic planovalgus foot deformities. …”
Publicado 2023
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936por Luyo-Peñafiel, Brigith R, Briceño-Vergel, Gissela, Ladera-Castañeda, Marysela Irene, Córdova-Limaylla, Nancy, Huamaní-Echaccaya, Jose Luis, Romero-Velásquez, Leysi, Hernández-Huamaní, Emily, Castro-Rojas, Miriam, Cervantes-Ganoza, Luis, Cayo-Rojas, César“…It is recommended that educational authorities include selected topics on CLP in subjects related to infant, child and adolescent care.…”
Publicado 2023
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937por Bitto, Alessandra, Minutoli, Letteria, David, Antonio, Irrera, Natasha, Rinaldi, Mariagrazia, Venuti, Francesco S, Squadrito, Francesco, Altavilla, Domenica“…INTRODUCTION: Cecal ligation and puncture (CLP) is an inflammatory condition that leads to multisystemic organ failure. …”
Publicado 2012
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938“…METHODS: To study this, male wild-type (WT) and RIPK3-deficient (Ripk3(-/-)) mice on C57BL/6 background were subjected to sham operation or cecal ligation and puncture (CLP)-induced sepsis. Blood and tissue samples were collected 20 hours post-CLP for various measurements. …”
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939“…Together, these results reveal a role for W102 in nuclear targeting of 5-LO1 suggesting that interactions with CLP are required for nuclear localization of 5-LO1, and are an initial characterisation of the 5-LO∆13 isoform whose inhibition of LT biosynthesis appears independent of interactions with CLP and FLAP. …”
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940“…RESULTS: The EBR system ameliorated CLP-induced sepsis compared with the sham EBR system. …”
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