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981por Liu, Zhiyong, Shi, Qiao, Liu, Jiao, Abdel-Razek, Osama, Xu, Yongan, Cooney, Robert N, Wang, Guirong“…CLP decreased pancreatic SP-D levels and caused severe pancreatic injury with higher serum amylase 24 h after CLP. …”
Publicado 2015
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982por Zhao, Wenjing, Dao, Christine, Karim, Murni, Gomez-Chiarri, Marta, Rowley, David, Nelson, David R.“…Complementation of the clpX and exoP mutations restored the wild type phenotype. …”
Publicado 2016
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983“…Furthermore, a mutation of a global regulator gene (clp) or a Gcn5-related N-acetyltransferase (GNAT) gene in L. enzymogenes led to nearly no growth in media containing chloramphenicol, whereas a complementation of clp restored the chloramphenicol acylation as well as antibiotic HSAF production in the clp mutant. …”
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984“…As compared with WT (C57Bl/6) mice, CXCL1 knockout mice display early mortality following acute alcohol exposure followed by CLP. Recombinant CXCL1 (rCXCL1) in acute alcohol challenged CLP mice increases survival, enhances bacterial clearance, improves neutrophil recruitment, and enhances NET formation (NETosis). …”
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985por Itakura, Junya, Sato, Miwa, Ito, Toshihiro, Mino, Megumi, Fushimi, Soichiro, Takahashi, Sakuma, Yoshimura, Teizo, Matsukawa, Akihiro“…Here, we examined whether the absence of Sprouty-related EVH1-domain-containing protein 2 (Spred2), a negative regulator of the Ras/Raf/ERK/MAPK pathway, influences host defense against polymicrobial sepsis (PMS) induced by cecal ligation and puncture (CLP). Compared to wild-type mice, Spred2(−/−) mice exhibited higher survival rates with increased level of leukocyte infiltration and local chemokine production and reduced plasma and peritoneal bacterial loads after CLP. …”
Publicado 2017
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986“…ABI was induced by cecal ligation and puncture (CLP). EA on bilateral Zusanli acupoints was performed following CLP. …”
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987por Diniz, Lúcio Ricardo Leite, Portella, Viviane Gomes, da Silva Alves, Kerly Shamira, Araújo, Pâmella Cristina da Costa, de Albuquerque Júnior, Ricardo Luiz Cavalcanti, Cavalcante de Albuquerque, Aline Alice, Coelho-de-Souza, Andrelina Noronha, Leal-Cardoso, José Henrique“…MATERIALS AND METHODS: Twenty-four hours after sepsis induced by cecal ligation and puncture (CLP) model, sciatic and vagus nerves of septic (CLP group) and control (sham group) rats were removed, and selected electric stimulations were applied to measure the parameters of the first and second components of the compound action potential. …”
Publicado 2018
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988por Jia, Yifan, Li, Zeyu, Feng, Yang, Cui, Ruixia, Dong, Yanyan, Zhang, Xing, Xiang, Xiaohong, Qu, Kai, Liu, Chang, Zhang, Jingyao“…Sepsis was induced in wild-type C57BL/6 mice by cecal ligation and puncture (CLP), and the mice were divided into three groups: a sham control group (sham), a surgery group with saline intraperitoneal injection (i.p.) treatment (CLP + NS), and a surgery group with MRS i.p. treatment (CLP + MRS). 24 h after the establishment of the sepsis, the blood and kidney tissues of mice in all groups were collected. …”
Publicado 2018
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989por Yang, Dingyi, Ho, Yin Xin, Cowell, Laura M., Jilani, Iqra, Foster, Simon J., Prince, Lynne R.“…The virulence of the clpP mutant was restored in a neutrophil-depleted zebrafish model, suggesting the importance of ClpP in mechanisms underpinning neutrophil immunity to S. aureus. …”
Publicado 2019
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990por Fu, Qun, Wu, Jing, Zhou, Xiao-Yan, Ji, Mu-Huo, Mao, Qing-Hong, Li, Qing, Zong, Man-Man, Zhou, Zhi-Qiang, Yang, Jian-Jun“…Mice were randomly assigned to one of six groups: sham+saline, sham+MCC950, sham+Ac-YVAD-CMK, cecal ligation and puncture (CLP)+saline, CLP+MCC950, and CLP+Ac-YVAD-CMK. Surviving mice underwent behavioral tests or had hippocampal tissues collected for histochemical analysis and biochemical assays. …”
Publicado 2018
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991por Espinoza-Espinoza, Gerardo, Corsini, Gilda, Rojas, Rubén, Mariño, Rodrigo, Zaror, Carlos“…Only direct costs were evaluated, expressed in Chilean pesos (CLP) at 7th May at 2019 values (exchange rate USD = CLP 681.09). …”
Publicado 2019
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992por Wang, Hongzhou, Zhang, Shunwen, Zhao, Haijun, Qin, Huiyuan, Zhang, Jie, Dong, Jiangtao, Zhang, Hui, Liu, Xiaoling, Zhao, Zhengyong, Zhao, Yanheng, Shao, Meng, Wu, Fang, Zhang, Wanjiang“…This study aimed to investigate the role of CO on the expression of proteins associated with intestinal mucosal pyroptosis in a rat model of sepsis induced by cecal ligation and puncture (CLP). MATERIAL/METHODS: The rat model of sepsis was developed using CLP. …”
Publicado 2020
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993por Zhang, Xue, Morits, Maria, Jonkergouw, Christopher, Ora, Ari, Valle-Delgado, Juan José, Farooq, Muhammad, Ajdary, Rubina, Huan, Siqi, Linder, Markus, Rojas, Orlando, Sipponen, Mika Henrikki, Österberg, Monika“…Overall, our results demonstrate that nanocomposite CNF-alginate-CLP scaffolds have high potential in soft-tissue engineering and regenerative-medicine applications.…”
Publicado 2020
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994por Tsujimoto, Hironori, Horiguchi, Hiroyuki, Matsumoto, Yusuke, Takahata, Risa, Shinomiya, Nariyoshi, Yamori, Takao, Miyazaki, Hiromi, Ono, Satoshi, Saitoh, Daizoh, Kishi, Yoji, Ueno, Hideki“…Similarly, at 24 and 72 h after operation, serum levels of HGF in CLP mice were significantly higher than those in sham-operated mice. …”
Publicado 2020
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995por de Jesus Oliveira, Flora Magno, Gonçalves-de-Albuquerque, Cassiano Felippe, de Moraes, Isabel Matos Medeiros, Reis, Patrícia Alves, Rocha, Vinicius Novaes, Bozza, Patrícia Torres, Silva, Adriana Ribeiro, de Castro Faria Neto, Hugo Caire“…We measured plasma biochemical markers of organ dysfunction, cell migration, cell activation, bacterial elimination, production of nitric oxide 24 h after CLP, survival rate for 7 days, and cognitive impairment 15 days after CLP. …”
Publicado 2020
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996por García-Laorden, M. Isabel, Rodríguez-González, Raquel, Martín-Barrasa, José L., García-Hernández, Sonia, Ramos-Nuez, Ángela, González-García, H. Celeste, González-Martín, Jesús M., Kacmarek, Robert M., Villar, Jesús“…For this purpose, sepsis was induced in male, Sprague-Dawley rats by cecal ligation and puncture (CLP). We randomly assigned experimental animals to three groups: control (healthy animals), septic (CLP), and sham-septic (surgical intervention without CLP). …”
Publicado 2020
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997por Liang, Guiwen, Wu, Ruo, Jiang, Lan, Liu, Yanfang, Mao, Guomin, Huang, Zhongwei, Qi, Lei, Jiang, Haiyan“…BACKGROUND: This experiment aimed to investigate the role and mechanism of lipoprotein-associated phospholipase A2 (Lp-PLA2) in kidney injury in septic mice induced by cecal ligation and perforation (CLP). METHODS: Male BALB/c mice were randomly divided into two groups: sham-operation group (Sham group) and septic group (CLP group). …”
Publicado 2020
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998por Chimenti, Laura, Morales-Quinteros, Luis, Puig, Ferranda, Camprubi-Rimblas, Marta, Guillamat-Prats, Raquel, Gómez, Maria Nieves, Tijero, Jessica, Blanch, Lluis, Matute-Bello, Gustavo, Artigas, Antonio“…Rats receiving only HCl or subjected to CLP had no evidence of lung injury. CONCLUSIONS: Rat models of ALI induced directly by LPS or HCl-LPS more closely reproduced the acute phase of human ARDS than the CLP model of indirectly induced ALI.…”
Publicado 2020
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999“…Sepsis was induced using cecal ligation and puncture (CLP). The animal’s hippocampi and blood were collected for subsequent investigations 24 h after surgery. …”
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1000por Kamal, Shady Mansour, Cimdins‐Ahne, Annika, Lee, Changhan, Li, Fengyang, Martín‐Rodríguez, Alberto J., Seferbekova, Zaira, Afasizhev, Robert, Wami, Haleluya Tesfaye, Katikaridis, Panagiotis, Meins, Lena, Lünsdorf, Heinrich, Dobrindt, Ulrich, Mogk, Axel, Römling, Ute“…We confirmed stand‐alone disaggregation activity, but observed distinct biochemical characteristics of ClpG(GI‐Fec10) compared to the nearly identical Pseudomonas aeruginosa ClpG(GI‐SG17M.) …”
Publicado 2020
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