Mostrando 1,081 - 1,100 Resultados de 2,845 Para Buscar '"CLP"', tiempo de consulta: 0.60s Limitar resultados
  1. 1081
    “…Our data collectively show CLP-induced sepsis alters the number and function of Ag-specific memory CD4 T cells, which contributes (in part) to the characteristic long-lasting immunoparalysis seen after sepsis.…”
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    Polymicrobial Sepsis Impairs Antigen-Specific Memory CD4 T Cell-Mediated Immunity
  2. 1082
    “…AIMS: The Cardiac Lipid Panel (CLP) is a newly discovered panel of metabolite‐based biomarkers that has shown to improve the diagnostic value of N terminal pro B type natriuretic peptide (NT‐proBNP). …”
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    Incremental prognostic value of a novel metabolite‐based biomarker score in congestive heart failure patients
  3. 1083
    “…METHODS: In this paper, we used cecal ligation puncture (CLP) to generate an ALI mouse model to determine the effects of luteolin on ALI/ARDS. …”
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    Luteolin Regulates the Differentiation of Regulatory T Cells and Activates IL-10-Dependent Macrophage Polarization against Acute Lung Injury
  4. 1084
    “…Overexpression of RUNX1 abolished the impacts of elevated miR-21-5p in CLP rats. Also, EPCs-exos upregulated miR-21-5p expression, and functioned similar to elevation of miR-21-5p for CLP rats. …”
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    Endothelial progenitor cells-derived exosomal microRNA-21-5p alleviates sepsis-induced acute kidney injury by inhibiting RUNX1 expression
  5. 1085
    “…METHODS: A cecal ligation and puncture (CLP) protocol was performed in 12 rats while 12 controls underwent sham operation. …”
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    Mechanical ventilation preserves diaphragm mitochondrial function in a rat sepsis model
  6. 1086
    “…The cardiac lipid panel (CLP) is a novel panel of metabolomic biomarkers that has previously shown to improve the diagnostic and prognostic value for CHF patients. …”
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    Performance of a cardiac lipid panel compared to four prognostic scores in chronic heart failure
  7. 1087
    “…RESULTS: Compared with the sham group, the lung of mice in the CLP group showed pulmonary morphological abnormalities, and the expression of IL-6 and IL-1β, caspase-3 activity, and apoptosis rate were significantly upregulated in the CLP group. …”
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    miR-128-3p reduced acute lung injury induced by sepsis via targeting PEL12
  8. 1088
    “…CLP or sham surgery was performed on pre-miR-335, anti-miR-335 and wild-type mice and miR-335 expression was determined by reverse transcription-quantitative PCR. …”
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    Upregulation of miR-335 exerts protective effects against sepsis-induced myocardial injury
  9. 1089
    “…Cecal ligation and puncture (CLP) was used to establish a sepsis model in rats. …”
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    Tong-fu-li-fei decoction attenuates immunosuppression to protect the intestinal-mucosal barrier in sepsis by inhibiting the PD-1/PD-L1 signaling pathway
  10. 1090
    “…Recently, some researchers have directed their interest toward a protein, calprotectin (CLP), as a potential biomarker. The primary objective of our systematic review and meta-analysis was to analyze the possible role of CLP in JIA. …”
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    Serum Calprotectin a Potential Biomarker in Juvenile Idiopathic Arthritis: A Meta-Analysis
  11. 1091
    “…RESULTS: Here we report hippocampal-dependent cognitive deficits and synaptic dysfunction induced by the CLP, accompanied by a significant increase in inflammatory factors. …”
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    Metformin attenuates sepsis-induced neuronal injury and cognitive impairment
  12. 1092
    “…PURPOSE: Dental restoration in cleft lip and palate (CLP) patients is demanding and often results in bone loss and dental implant failure. …”
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    Novel approach for treating challenging implant-borne maxillary dental rehabilitation cases of cleft lip and palate: a retrospective study
  13. 1093
    “…LPS treatment or CLP induction decreased the expression of Foxc1 and inhibitor of NF-κB (IκΒα) whilst increasing that of p65, IL-1β and TNF-α. …”
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    Overexpression of Foxc1 ameliorates sepsis-associated encephalopathy by inhibiting microglial migration and neuroinflammation through the IκBα/NF-κB pathway
  14. 1094
    “…Isometric tension in isolated aortic rings was measured by wire myography.CLP down-regulated aortic expression of Notch3, Jag1 and Dll4 as compared to control mice. …”
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    Sepsis downregulates aortic Notch signaling to produce vascular hyporeactivity in mice
  15. 1095
    “…We developed a mouse model of sepsis through cecal ligation and puncture (CLP) to investigate dynamic changes in autophagy in CD4 + T cells. …”
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    mTOR deletion ameliorates CD4 + T cell apoptosis during sepsis by improving autophagosome-lysosome fusion
  16. 1096
    “…Experimental sepsis was induced in C57BL/6 mice by cecal ligation and puncture (CLP). RESULTS: CLP significantly induced systemic inflammation, lung permeability, and lung epithelial apoptosis with downregulated messenger RNA (mRNA) levels of antioxidant enzymes. …”
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    Deletion of the miR-144/451 cluster aggravates lethal sepsis-induced lung epithelial oxidative stress and apoptosis
  17. 1097
    “…The in vitro LPS-induced HK-2 cell model and in vivo CLP-induced mouse model were established. qRT-PCR, Western blot, ELISA, and RNA pulldown were used for expression examination. …”
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    miR-181a-5p Inhibits Pyroptosis in Sepsis-Induced Acute Kidney Injury through Downregulation of NEK7
  18. 1098
    “…To investigate the underlying role of protein phosphorylation in SAE and H(2) treatment, a mouse model of sepsis was constructed by caecal ligation and puncture (CLP), then treated with H(2) (CLP + H(2)). Brain tissues of the mice were collected to be analysed with tandem mass tag‐based quantitative proteomics coupled with IMAC enrichment of phosphopeptides and LC–MS/MS analysis. …”
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    Phosphorylation‐mediated PI3K‐Art signalling pathway as a therapeutic mechanism in the hydrogen‐induced alleviation of brain injury in septic mice
  19. 1099
    “…Furthermore, these 3 metabolites including Palmitoylethanolamide, Deoxycholic acid and Chenodeoxycholic acid correlated significantly to CLP- and GM-rich genus (P < 0.05). Besides, the lung tissues of CLP group showed more severe inflammatory infiltration and edema, and the mortality rate in the CLP group (10/20) was significantly higher than in the SC group (0/20) (P < 0.001) and GM group (4/20) (P < 0.05). …”
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    Effects of Gabexate Mesylate on the Gut Microbiota and Metabolomics in Rats with Sepsis
  20. 1100
    “…The inflammation response and multi-organ injury induced by CLP treatment could be partially counteracted by 0.5 g/kg parenteral ω-3 PUFA treatment. …”
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    Protective effect of omega-3 polyunsaturated fatty acids on sepsis via the AMPK/mTOR pathway
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