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1321por Chen, Chaojin, Qiu, Rongzong, Yang, Jing, Zhang, Qian, Sun, Guoliang, Gao, Xiaofeng, Hei, Ziqing, Ji, Haocong“…While, on the one hand, inhibition of senescence with rapamycin restored renal function and attenuated septic inflammatory response, on the other hand, LXA4 administration inhibited renal inflammation and tubular epithelial cell senescence after CLP. Ultimately, pretreatment with LXA4 significantly restored renal function and increased the survival rate of rats after CLP. …”
Publicado 2021
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1322por Hagihara, Mao, Ariyoshi, Tadashi, Kuroki, Yasutoshi, Eguchi, Shuhei, Higashi, Seiya, Mori, Takeshi, Nonogaki, Tsunemasa, Iwasaki, Kenta, Yamashita, Makoto, Asai, Nobuhiro, Koizumi, Yusuke, Oka, Kentaro, Takahashi, Motomichi, Yamagishi, Yuka, Mikamo, Hiroshige“…Additionally, CBM 588 upregulated T cell-dependent pathogen specific immunoglobulin A (IgA) via interleukin (IL)-17A producing CD4(+) cells and plasma B cells in the cLP, and Th17 cells in the cLP enhanced the gut epithelial barrier function. …”
Publicado 2021
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1323por Skirecki, Tomasz, Drechsler, Susanne, Jeznach, Aldona, Hoser, Grażyna, Jafarmadar, Mohammad, Kawiak, Jerzy, Osuchowski, Marcin F.“…The 12-week-old outbred CD-1 female mice (n=65) were subjected to a cecal ligation and puncture (CLP) sepsis, treated with antibiotics and fluid resuscitation, and stratified into predicted-to-die (P-DIE) and predicted-to-survive (P-SUR) cohorts for analysis. …”
Publicado 2021
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1324“…Cecal ligation and puncture (CLP) is a classic animal model of sepsis, which can induce ALI. …”
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1325por Dastpak, Arman, Ansell, Philip, Searle, Justin R., Lundström, Mari, Wilson, Benjamin P.“…Overall, these results highlight the potential of TOCN–CLP biopolymeric composites as a basis for sustainable corrosion protection coatings.…”
Publicado 2021
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1326por Sekulovski, Samoil, Devant, Pascal, Panizza, Silvia, Gogakos, Tasos, Pitiriciu, Anda, Heitmeier, Katharina, Ramsay, Ewan Phillip, Barth, Marie, Schmidt, Carla, Tuschl, Thomas, Baas, Frank, Weitzer, Stefan, Martinez, Javier, Trowitzsch, Simon“…Introns of human transfer RNA precursors (pre-tRNAs) are excised by the tRNA splicing endonuclease TSEN in complex with the RNA kinase CLP1. Mutations in TSEN/CLP1 occur in patients with pontocerebellar hypoplasia (PCH), however, their role in the disease is unclear. …”
Publicado 2021
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1327“…METHODS: Sepsis was induced in aged wild-type (WT) and IRF3-knock-out (KO) mice, using a clinically-relevant CLP-sepsis model including fluids and antibiotics. …”
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1328“…Dexmedetomidine (DEX) has been reported to attenuate cecal ligation perforation (CLP)-stimulated acute lung injury (ALI) by downregulating HMGB1 and RAGE. …”
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1329“…RESULTS: CLP significantly increased circulating levels of human resistin. …”
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1330por Matto, Carolina, D'Alessandro, Bruno, Mota, María Inés, Braga, Valeria, Buschiazzo, Alejandro, Gianneechini, Edgardo, Varela, Gustavo, Rivero, Rodolfo“…Instead, both strains carried a set of genes that encode for other virulence factors of the genus Listeria detected using the Virulence Factor Database (VFDB): iap (division and invasion of host cells), lpeA (entry into non‐professional phagocytes cells), fbpA (multifunctional virulence factor, including adherence to host cells), lspA (surface protein anchoring), lap (adhesion to enterocytes and trans epithelial translocation), pdgA (resistance to lysozyme), oatA (resistance to different antimicrobial compounds and also required for growth inside macrophages), lplA1 (use of host‐metabolites for in vivo growth), gtcA (catalyses teichoic acid of bacterial wall), prsA2 (cell invasion, vacuole lysis and intracellular growth), clpC, clpE and clpP (survival under several stress conditions). …”
Publicado 2022
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1331por Sun, Yali, Ding, Xianfei, Cui, Yuqing, Li, Hongyi, Wang, Dong, Liang, Huoyan, Liu, Shaohua, Zhang, Xiaojuan, Wang, Haixu, Sun, Tongwen“…METHODS: Sixty Sprague-Dawley (SD) rats were randomly divided into sham control (SC), sepsis (CLP), and sepsis+Sivelestat (Sive) groups. The rats’ survival status was monitored for 24 hours postoperatively, and feces were collected for microbiome and non-targeted metabolomics analyses. …”
Publicado 2022
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1332por Vale, A.H.F., Nascimento, D.C., Pineros, A.R., Ferreira, R.G., Santos, J.D., Aragon, D.C., Cunha, F.Q., Ramalho, F.S., Alves-Filho, J.C., Carlotti, A.P.C.P.“…C57BL/6 mice, 6-8 weeks old, were allocated to the study group (polymicrobial sepsis induced by cecal ligation and puncture (CLP) + antibiotic + iv riboflavin), control (CLP + antibiotic + iv saline), or naïve (non-operated controls). …”
Publicado 2022
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1333“…The four key genes were confirmed increased in the heart of CLP rats (p < 0.05 or 0.01). The results suggest that the lipid metabolism disorder participates in the occurrence of AF. …”
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1334por Li, Lei, Huang, Lin, Huang, Chenyang, Xu, Jia, Huang, Yukai, Luo, Haihua, Lu, Xinya, He, Shuyue, Yuan, Gang, Chen, Li, Han, Xue, Cao, Xusong, Jiang, Aolin, Liu, Cuiting, Shi, Junmin, Yang, Hong, Jiang, Yong“…Importantly, pretreatment with serum exosomes derived from mice subjected to CLP significantly restrained proinflammatory cytokine expression and alleviated tissue injury in septic mice. …”
Publicado 2021
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1335“…Background: A transitory period prior to the surgical correction of cleft lip and palate (CLP) is associated with adverse impacts, which may require a medical intervention. …”
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1336por Zeng, Jun, Yang, Zhiqiang, Zhong, Yue, Zheng, Yingli, Hao, Jingwen, Luo, Gang, Yan, Qingpi“…The silencing of the P. plecoglossicida clpV gene significantly recovered the lipid metabolism of infected E. coioides. …”
Publicado 2022
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1337por Leisman, Daniel E., Privratsky, Jamie R., Lehman, Jake R., Abraham, Mabel N., Yaipan, Omar Y., Brewer, Mariana R., Nedeljkovic-Kurepa, Ana, Capone, Christine C., Fernandes, Tiago D., Griffiths, Robert, Stein, William J., Goldberg, Marcia B., Crowley, Steven D., Bellomo, Rinaldo, Deutschman, Clifford S., Taylor, Matthew D.“…Ex vivo, angiotensin-II increased post-CLP monocyte phagocytosis and ROS production after lipopolysaccharide stimulation. …”
Publicado 2022
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1338por Shi, Xiaocui, Li, Juncong, Han, Yuzhen, Wang, Jingyi, Li, Qingping, Zheng, Yue, Li, Wenxiong“…However, the ameliorative effect of α7nAChR on sepsis-induced AKI (SAKI) in the cecal ligation and puncture (CLP) model is unclear. The previous studies have demonstrated that α7nAChR is highly expressed on the surface of CD4(+)CD25(+) regulatory T cells (Tregs). …”
Publicado 2022
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1339por Parasuraman, Paramanantham, Devadatha, B, Sarma, V. Venkateswara, Ranganathan, Sampathkumar, Ampasala, Dinakara Rao, Reddy, Dhanasekhar, Kumavath, Ranjith, Kim, In-Won, Patel, Sanjay K. S., Kalia, Vipin Chandra, Lee, Jung-Kul, Siddhardha, Busi“…The MIC values of CLP and 4-HPA against P. aeruginosa PAO1 were determined as 250 and 125 μg/ml, respectively. …”
Publicado 2020
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1340por Otsuki, Bungo, Fujibayashi, Shunsuke, Shimizu, Takayoshi, Murata, Koichi, Matsuda, Shuichi“…The present study compared the clinical outcomes of cervical laminoplasty (CLP) using a closed suction drain (CSD) and closed nonsuction drain (CNSD). …”
Publicado 2022
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