“…The thickness of the endovascular glycocalyx was visualized by intravital microscopy in lung (LPS inhalation model) or cremaster muscle (CLP model). Syndecan-1, hyaluronic acid, and heparanase levels were measured in blood samples. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Methods and Results: C57/BL6 mice were (1) injected with LPS followed by 24-h TMZ administration, or (2) treated with TMZ (20 mg/kg/day) for 1 week post cecal ligation and puncture (CLP) operation. Echocardiography and Millar system detection showed that TMZ alleviated cardiac dysfunction and histological staining showed the failure of neutrophils migration to heart in both LPS- and CLP-induced mice. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…An optimal cut-off value for annual CIMT change of > 0.003 mm/year (sensitivity: 84.5%, specificity: 49.3%) for MI plus CLP (AUC = 0.673) occurred an independent indicator of MACCE (HR = 3.00; 95% CI: 1.496–6.016), recurrent MI (HR = 4.59, 95% CI: 1.591–13.217), and MI plus CLP (HR = 3.50, 95% CI: 1.759–6.964). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…To examine the effect of sepsis and corticosteroid treatment on adrenal function, we used a naturalistic mouse model of sepsis, cecal ligation and puncture (CLP). Male and female C57Bl/6 mice (N = 20 per group, 10 male/10 female) underwent CLP or sham surgery and were treated with daily injections of either corticosterone (13 mg/kg) or vehicle for five days. …”
Enlace del recurso
Enlace del recurso

“…Sepsis was then induced by cecal ligation and puncture (CLP). At -10, 0, and 10 h relative to CLP, rats received MFG-E8 or vehicle (albumin) intravenously. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Compared with infection patients and healthy controls, PBMC from sepsis patients also had higher levels of mitogen-activated kinase kinase kinase 7 (MAP3K7), a known target protein of miR-10a and an activator of the NF-κB pathway. In the mouse model of CLP-induced sepsis, miR-10a levels in PBMC were significantly decreased as early as 8 h after CLP. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Using 5-ethynyl-2′-deoxyuridine (EdU) incorporation, we found that the CD54(hi) population on day 2 after CLP may be participating in emergency myelopoiesis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In individuals with cleft lip and palate (CLP) an iatrogenic effect of operations on subsequent maxillary growth is well-known. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…There was a significant dose-dependent decrease in mortality and ALI after CLP with SQV. SQV significantly inhibited LPS-mediated M1 phenotype and increased M2 phenotype in cultured RAW 264.7 and primary murine bone marrow-derived macrophages as well as lung macrophages from CLP-treated mice. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Elevation of pulmonary MMP-9 mRNA and protein expressions was confirmed in CLP-induced mouse sepsis model. Intratracheal injection of MMP-9 siRNA resulted in an approximately 60% decrease in pulmonary MMP-9 expression. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We also explored the downstream cytokines released by neutrophils following miR-let-7b treatment and its therapeutic effects in cecal ligation and puncture (CLP)-induced septic mice. Six-to-eight-week-old male C57BL/6 mice underwent CLP following treatment with miR-let-7b agomir. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: The CLP operation was performed to establish the sepsis mice model, and the survival rate and temperature were measured after 7-OBA treatment (7.5, 15, and 30 mg/kg; i.p.). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: The COVID-19 pandemic halted all in person and group Child Life Programs (CLP) for pediatric patients at a high acuity children's hospital. …”
Enlace del recurso
Enlace del recurso

“…OBJECTIVE: To systematically assess the efficacy and safety of dexmedetomidine as an anaesthesia adjuvant for cleft lip and palate (CLP) repair in children. DESIGN: Systematic review and meta-analysis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…It was noted that WWP1 and YTHDF1 were downregulated in clinical sepsis samples, LPS + ATP-treated RAW264.7 cells, and CLP-induced mice. The ubiquitination of NLRP3 was promoted after overexpression of WWP1. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The cecal ligation and puncture (CLP) model is currently the gold standard for sepsis studies. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In vivo, we established male C57BL/6 mice cecal ligation puncture (CLP) model of sepsis. We found that inhibition of CCL25 significantly reduced inflammatory cytokine expression in a CLP-induced sepsis model, thereby alleviating lung tissue damage in mice. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Thus, we speculated that GAS6-AS2 might function in sepsis-related AKI via regulating target genes. Here, LPS or CLP was used to establish in vitro or in vivo sepsis-related AKI model. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BPF treatment also dose-dependently improved the survival rates in mice with CLP-induced sepsis. These results show that BPF alleviates LPS-stimulated septic conditions and protects mice from CLP-induced sepsis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…MATERIALS AND METHODS: SAE was induced in C57BL/6 mice by cecal ligation and puncture(CLP). Mice were administrated with β-PAE or saline by intra-cerebral ventricle(i.c.v) injection immediately after CLP surgery. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso