“…AIM: The aim of this study is to evaluate the various dentofacial deformities in children who were surgically managed for cleft lip and palate (CLP). MATERIALS AND METHODS: The study was carried out in 100 surgically managed cleft lip palate children between the ages of 4 years and 15 years. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Administration of rmIL‐38 improved the survival rate of CLP mice. In addition, CD4(+)CD25(+) Tregs depletion before the onset of sepsis obviously abolished IL‐38–mediated protective response. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We show that binding of pyrazinoic acid to PanD triggers degradation of the protein by the caseinolytic protease ClpC1-ClpP. Thus, the old tuberculosis drug pyrazinamide exerts antibacterial activity by acting as a target degrader, a mechanism of action that has recently emerged as a successful strategy in drug discovery across disease indications. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Our results show that CLP led to two consecutive phases of Mo deployment. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the present study, SAE was established in mice through caecal ligation and puncture (CLP). The adeno‐associated virus 2 (AAV2)‐mediated SESN2 expression (ie overexpression and knockdown) system was injected into the hippocampi of mice with SAE, and subsequently followed by electron microscopic analysis, the Morris water maze task and pathological examination. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this study, high-throughput gene sequencing was used to analyze the expression profiles of circRNAs in lung specimens of mice grouped by acute lung injury induced by cecal ligation and puncture (CLP) and sham. To identify differentially expressed circRNAs, the left lungs of sham (n = 3) and CLP (n = 3) mice were used for high-throughput sequencing. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we screened a cross-kingdom collection of Hsp104 homologs in yeast proteotoxicity models. Prokaryotic ClpG reduced TDP-43, FUS, and α-synuclein toxicity, whereas prokaryotic ClpB and hyperactive variants were ineffective. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The present study was performed to investigate whether Senkyunolide I protected against SAE in a murine model of cecal ligation and puncture (CLP). Here, we showed that Senkyunolide I treatment improved the 7-day survival rate and reduced the excessive release of cytokines including TNF-α, IL-6, and IL-1β. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Five cleft types were considered: unilateral CLP (right; URCLP and left; ULCLP), bilateral CLP (BCLP), isolated cleft palate (CP) and isolated cleft lip (CL). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this study, mouse models of sepsis were established by caecal ligation and puncture (CLP). The H&E staining of sections and serum diamine oxidase concentration were evaluated at different timepoint after CLP. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The imipridone ONC201 is a G-protein-coupled dopamine receptor D2 modulator and an allosteric agonist of the mitochondrial protease caseinolytic protease P(ClpP), which induces apoptosis. Here, we aimed to develop a novel ONC201-based combination therapy targeting TNBC. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Long-lasting depression-like behaviors were detected in the CLP mice, as well as significant increases in neuronal apoptosis and necroptosis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Only the three smRLs (Rh-Eth-C12, Rh-Est-C12 and Rh-Succ-C12), the two CLP mixtures and the BioA187 led to a partial protection of wheat against Bgt. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The expression pattern of miR-377 was detected in myocardial tissues of septic mice induced by cecal ligation-perforation (CLP). We found that miR-377 was highly expressed in myocardial tissues of CLP-induced septic mice with cardiomyocyte hypertrophy. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: We found that macrophage Spry4 was increased in CLP mice and positively correlated with sepsis-induced ALI. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: Clinical sample, cecal ligation and puncture (CLP)‐induced animal models and lipopolysaccharides (LPS)‐induced cell models were prepared for testing relative expression of extracellular histone H3 and E2 as well as analyzing the role of extracellular histone H3 and E2 in sepsis concerning cell viability, reactive oxygen species (ROS), and ferroptosis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This study aims to obtain a novel probiotic strain adapted to marine habitats and to assess its antisepsis properties using a cecal ligation and puncture (CLP) model in rodents. The marine Enterococcus faecium EA9 was isolated from marine shrimp samples and evaluated for probiotic potential after phenotypical and molecular identification. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: Mice were subjected to cecal ligation and puncture (CLP) with daily chronic stress (DCS) as an in vivo model to study sepsis late‐effects/sequelae on skeletal muscle components. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: Sepsis was induced in BALB/c mice using cecal ligation and puncture (CLP), followed by intraperitoneal injection of different doses (10, 25 or 50 μg) of recombinant Sj-Cys (rSj-Cys). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Platycodon has an IR containing a 3′ rps12 operon, which occurs in the middle of the LSC region in four other species of Campanulaceae (T. caeruleum, A. remotiflora, C. takesimana, and H. asiatica), but lacks accD, clpP, infA, and rpl23, as has been found in these four species. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso