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1601por Little, Hayley J., Rorick, Nicholas K., Su, Ling-I, Baldock, Clair, Malhotra, Saimon, Jowitt, Tom, Gakhar, Lokesh, Subramanian, Ramaswamy, Schutte, Brian C., Dixon, Michael J., Shore, Paul“…Cleft lip and cleft palate (CLP) are common disorders that occur either as part of a syndrome, where structures other than the lip and palate are affected, or in the absence of other anomalies. …”
Publicado 2009
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1602por Coleman, James L., Katona, Laura I., Kuhlow, Christopher, Toledo, Alvaro, Okan, Nihal A., Tokarz, Rafal, Benach, Jorge L.“…On the chromosome, lon-2 is immediately downstream of ATP-dependent proteases clpP and clpX, an arrangement identical to that of lon of Escherichia coli. …”
Publicado 2009
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1603por Kelly-Scumpia, Kindra M., Scumpia, Philip O., Delano, Matthew J., Weinstein, Jason S., Cuenca, Alex G., Wynn, James L., Moldawer, Lyle L.“…We used a low lethality cecal ligation and puncture (CLP) model of sepsis to determine the role of type I IFNs in host defense during sepsis. …”
Publicado 2010
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1604por Li, Chunmei, Qi, Yifei, Teng, Xin, Yang, Zongchang, Wei, Ping, Zhang, Changsheng, Tan, Lei, Zhou, Lu, Liu, Ying, Lai, Luhua“…In contrast to the matured 3CL(pro), the polyprotein, as well as the one-step digested product, 3CLP-Y-His, were shown to be monomeric in gel filtration and analytic ultracentrifuge analysis. …”
Publicado 2010
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1605por Dettman, E.J., Simko, Stephen J., Ayanga, Bernard, Carofino, Brandi, Margolin, Judith, Morse, Herbert C., Justice, Monica J.“…Prior to the onset of leukemia, differentiation of transduced cells was biased up to 1000-fold towards cells with features of common lymphoid progenitors (CLP), and lymphoid differentiation showed a relative block at the pro-B stage. …”
Publicado 2011
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1606por Aschkenasy, Gabriella, Bromberg, Zohar, Raj, Nichelle, Deutschman, Clifford S., Weiss, Yoram G.“…Sepsis was induced in rats via cecal ligation and double puncture (2CLP). At the time of 2CLP PBS, AdHSP or AdGFP (an adenoviral vector expressing green fluorescent protein) were injected into the tracheas of septic rats. 48 hours later, lungs were isolated. …”
Publicado 2011
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1607por Atmatzidis, Stefanos, Koutelidakis, Ioannis M, Chatzimavroudis, Grigorios, Kotsaki, Antigone, Louis, Konstantinos, Pistiki, Aikaterini, Savva, Athina, Antonopoulou, Anastasia, Atmatzidis, Konstantinos, Giamarellos-Bourboulis, Evangelos J“…METHODS: Abdominal sepsis was induced after cecal ligation and puncture (CLP) in 31 rabbits. Blood was sampled at serial time intervals and peripheral blood mononuclear cells (PBMCs) were isolated. …”
Publicado 2011
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1608por Castoldi, Angela, Braga, Tárcio Teodoro, Correa-Costa, Matheus, Aguiar, Cristhiane Fávero, Bassi, Ênio José, Correa-Silva, Reinaldo, Elias, Rosa Maria, Salvador, Fábia, Moraes-Vieira, Pedro Manoel, Cenedeze, Marcos Antônio, Reis, Marlene Antônia, Hiyane, Meire Ioshie, Pacheco-Silva, Álvaro, Gonçalves, Giselle Martins, Câmara, Niels Olsen Saraiva“…C57BL/6 TLR2(−/−), TLR4(−/−) and MyD88(−/−) male mice were subjected to sepsis by cecal ligation and puncture (CLP). Twenty four hours later, kidney tissue and blood samples were collected for analysis. …”
Publicado 2012
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1609por Adam, Céline, Picard, Marguerite, Déquard-Chablat, Michelle, Sellem, Carole H., Denmat, Sylvie Hermann-Le, Contamine, Véronique“…All multicellular eukaryotes, including filamentous fungi, possess the same set of mitochondrial proteases, unlike in unicellular yeasts, where ClpXP, one of the two matricial proteases, is absent. …”
Publicado 2012
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1610por Nakahashi-Oda, Chigusa, Tahara-Hanaoka, Satoko, Shoji, Masamichi, Okoshi, Yasushi, Nakano-Yokomizo, Takako, Ohkohchi, Nobuhiro, Yasui, Teruhito, Kikutani, Hitoshi, Honda, Shin-ichiro, Shibuya, Kazuko, Nagata, Shigekazu, Shibuya, Akira“…After cecal ligation and puncture (CLP), when a large number of cells undergo apoptosis in the peritoneal cavity, CD300a-deficient peritoneal mast cells produced more chemoattractant and recruited more neutrophils than did wild-type (WT) mast cells. …”
Publicado 2012
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1611“…OBJECTIVE: A national survey was conducted to assess orthodontic residents' current concepts and knowledge of cleft lip and palate (CLP) management in Korea. METHODS: A questionnaire consisting of 7 categories and 36 question items was distributed to 16 senior chief residents of orthodontic department at 11 dental university hospitals and 5 medical university hospitals in Korea. …”
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1612por Viniol, Annika, Jegan, Nikita, Leonhardt, Corinna, Brugger, Markus, Strauch, Konstantin, Barth, Jürgen, Baum, Erika, Becker, Annette“…Current research distinguishes between chronic localized pain (CLP) and chronic widespread pain (CWP). The aim of this study was to identify differences between CWP and chronic low back pain (CLBP), a common type of CLP, in primary care settings. …”
Publicado 2013
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1613“…Suramin does not disrupt Hsp104 hexamers and does not effectively inhibit ClpB, the E. coli homolog of Hsp104, establishing yet another key difference between Hsp104 and ClpB behavior. …”
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1614“…An animal model of cecal ligation-perforation (CLP)-induced sepsis was established. Two hours prior to surgery, animals in the treatment group were administered 25 mg/kg Melilotus extract tablets and subsequently every 8 h. …”
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1615“…Male Sprague-Dawlay (SD) rats were treated with berberine for 5 d before undergoing cecal ligation and puncture (CLP) to induce polymicrobial sepsis. The expression of Toll-like receptor 2 (TLR 2), TLR 4, TLR 9, the activity of nuclear factor-kappa B (NF-κB), the levels of selected cytokines and chemokines, percentage of cell death in intestinal epithelial cells, and mucosal permeability were investigated at 0, 2, 6, 12 and 24 h after CLP. …”
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1616por Stoll, Christian, Mengsteab, Senait, Stoll, Doris, Riediger, Dieter, Gressner, Axel M, Weiskirchen, Ralf“…CONCLUSIONS: The genetic differences in codons 25 and 263 suggest that TGF-β1 could play an important role in occurrence of CLP, however, functional experiments will be required to confirm the mechanisms of disturbed development.…”
Publicado 2004
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1617“…This study aimed to explore the effect and mechanisms of rhein on sepsis-induced acute kidney injury by injecting lipopolysaccharide (LPS) and cecal ligation and puncture (CLP) in vivo, and on LPS-induced HK-2 cells in vitro. …”
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1618“…Nevertheless, the cp genome of Dianthus and Spinacia has two introns in the proteolytic subunit of ATP-dependent protease (clpP) gene, but Lychnis has lost introns from the clpP gene. …”
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1619por Kadono, Takashi, Miyagawa-Yamaguchi, Arisa, Kira, Nozomu, Tomaru, Yuji, Okami, Takuma, Yoshimatsu, Takamichi, Hou, Liyuan, Ohama, Takeshi, Fukunaga, Kazunari, Okauchi, Masanori, Yamaguchi, Haruo, Ohnishi, Kohei, Falciatore, Angela, Adachi, Masao“…Moreover, the identified ClP1 promoter can serve as a novel tool for metabolic engineering of diatoms. …”
Publicado 2015
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1620“…The relBE2sca operon transcription was induced under osmotic stress, along with the ClpP proteinase genes. The subsequent in vivo analysis showed that the antitoxin was degraded by ClpP. …”
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