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1721por Takano, Ai, Toyomane, Kochi, Konnai, Satoru, Ohashi, Kazuhiko, Nakao, Minoru, Ito, Takuya, Andoh, Masako, Maeda, Ken, Watarai, Masahisa, Sato, Kozue, Kawabata, Hiroki“…A multilocus sequence analysis using 8 genes (clpA, clpX, nifS, pepX, pyrG, recG, rplB, and uvrA) suggested that all Japanese B. miyamotoi isolates, including past isolates, were genetically clonal, although these were isolated from different tick and vertebrate sources. …”
Publicado 2014
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1722por Coletta, Ciro, Módis, Katalin, Oláh, Gábor, Brunyánszki, Attila, Herzig, Daniela S, Sherwood, Edward R, Ungvári, Zoltán, Szabo, Csaba“…METHODS: Cecal ligation and puncture (CLP) was used to induce sepsis in mice. Survival rates were monitored and plasma indices of organ function were measured. …”
Publicado 2014
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1723por Starr, Marlene E., Steele, Allison M., Saito, Mizuki, Hacker, Bill J., Evers, B. Mark, Saito, Hiroshi“…While cecal-ligation and puncture (CLP) is considered the gold standard model for sepsis research, it may not be preferable for experiments comparing animals of different size or under different dietary regimens. …”
Publicado 2014
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1724por Li, Liping, Hong, Yuzhi, Luan, Gan, Mosel, Michael, Malik, Muhammad, Drlica, Karl, Zhao, Xilin“…The detrimental action of EF4 required transfer-messenger RNA (tmRNA, which tags truncated proteins for degradation and is known to be inhibited by EF4) and the ClpP protease. Inhibition of a protective, tmRNA/ClpP-mediated degradative activity would allow truncated proteins to indirectly perturb the respiratory chain and thereby provide a potential link between EF4 and ROS. …”
Publicado 2014
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1725por Kianifar, Hamidreza, Hasanzadeh, Nadia, Jahanbin, Arezoo, Ezzati, Atefeh, Kianifar, Homa“…Cleft lip associated with cleft palate (CLP) was the most prevalent type of cleft (50%), followed by isolated cleft lip (35.2%) and isolated cleft palate (14.8%). …”
Publicado 2015
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1726“…Overweight women were also at increased odds of pregnancy affected by CLP (OR = 1.06; 95% CI 0.93, 1.21) but not CP (OR = 0.89; 95% CI 0.75, 1.06). …”
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1727por Liu, Luwei, Zhang, Qian, Lin, Jiuxiang, Ma, Lian, Zhou, Zhibo, He, Xuesong, Jia, Yilin, Chen, Feng“…In this study, we sought to investigate the oral microbiota structure of children with cleft lip and palate (CLP) and explore the pre-operative oral bacterial composition related to the prognosis of alveolar bone grafting. …”
Publicado 2016
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1728por de Souza, Priscila, Guarido, Karla Lorena, Scheschowitsch, Karin, da Silva, Luísa Mota, Werner, Maria Fernanda, Assreuy, Jamil, da Silva-Santos, José Eduardo“…We investigated long-lasting changes in endothelial and vascular function in adult rat survivors of severe sepsis induced by cecal ligation and puncture (CLP) model. For this, male Wistar rats (200–350 g) had their cecum punctured once (non-transfixing hole) with a 14-gauge needle. …”
Publicado 2016
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1729por Rios, Carlos E. P., Abreu, Afonso G., Braga Filho, Jose A. F., Nascimento, Johnny R., Guerra, Rosane N. M., Amaral, Flávia M. M., Maciel, Márcia C. G., Nascimento, Flávia R. F.“…The animals received saline, HCE or HEX (5 mg/kg), subcutaneously (SC), 6 h before cecal ligation and puncture (CLP). Twelve hours after the CLP, the blood was collected to measure the serum cytokines and the animals were killed for the evaluation of colony-forming units (CFUs), cellular influx, and activation of phagocytes in the peritoneal cavity, measured by the secretion of hydrogen peroxide and nitric oxide production. …”
Publicado 2017
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1730por Hinkelbein, Jochen, Böhm, Lennert, Braunecker, Stefan, Adler, Christoph, De Robertis, Edoardo, Cirillo, Fabrizio“…Material and Methods. 26 male Wistar rats were assigned to either a sham group (control, N = 6) or sepsis group (N = 20; cecal ligature and puncture model, 24 and 48 hours after CLP). Surviving rats (n = 12) were decapitated at 24 hours (early phase; n = 6) or 48 hours (late phase; n = 6) after CLP and kidneys removed for proteomic analysis. 2D-DIGE and DeCyder 2D software (t-test, P < 0.01) were used for analysis of significantly regulated protein spots. …”
Publicado 2017
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1731por Souza, Maria C., Fonseca, Denise M., Kanashiro, Alexandre, Benevides, Luciana, Medina, Tiago S., Dias, Murilo S., Andrade, Warrison A., Bonfá, Giuliano, Silva, Marcondes A. B., Gozzi, Aline, Borges, Marcos C., Gazzinelli, Ricardo T., Alves-Filho, José C., Cunha, Fernando Q., Silva, João S.“…In this study, we showed that mice chronically infected with Toxoplasma gondii were more susceptible to sepsis induced by cecal ligation and puncture (CLP). Although T. gondii-infected mice exhibited efficient control of the bacterial burden, they showed increased mortality compared to the control groups. …”
Publicado 2017
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1732por Mercer, Stewart W., Fitzpatrick, Bridie, Grant, Lesley, Chng, Nai Rui, O’Donnell, Catherine A., Mackenzie, Mhairi, McConnachie, Alex, Bakhshi, Andisheh, Wyke, Sally“…Study population: For intervention practices, staff and adult patients involved in referral to a CLP, and a sample of community organization staff. …”
Publicado 2017
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1733por Niu, Zhitao, Pan, Jiajia, Zhu, Shuying, Li, Ludan, Xue, Qingyun, Liu, Wei, Ding, Xiaoyu“…The 10 loci—ndhA intron, matK-5′trnK, clpP-psbB, rps8-rpl14, trnT-trnL, 3′trnK-matK, clpP intron, psbK-trnK, trnS-psbC, and ndhF-rpl32—that had the highest degrees of sequence variability were identified as mutational hotspots for the Apostasia plastome. …”
Publicado 2017
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1734por Au, Amanda E., Lebois, Marion, Sim, Starling A., Cannon, Ping, Corbin, Jason, Gangatirkar, Pradnya, Hyland, Craig D., Moujalled, Diane, Rutgersson, Angelika, Yassinson, Fatme, Kile, Benjamin T., Mason, Kylie D., Ng, Ashley P., Alexander, Warren S., Josefsson, Emma C.“…Absent TPO signaling in Mpl (−/−) mice led to enrichment of a common lymphoid progenitor (CLP) signature in multipotential lineage-negative Sca-1(+)c-Kit(+) (LSK) cells and an increase in CLP formation. …”
Publicado 2017
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1735“…METHODS: Sepsis was induced by cecal ligation and perforation (CLP) or by a single intraperitoneal injection of lipopolysaccharide (LPS, 8 mg/kg) in C57BL/6J mice. …”
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1736por Apatsidou, Margarita, Konstantopoulou, Ioanna, Foufa, Eleni, Tsarouhas, Konstantinos, Papalexis, Petros, Rezaee, Ramin, Spandidos, Demetrios A., Kouretas, Demetrios, Tsitsimpikou, Christina“…The findings showed that over 85% of the responders were not aware of classification, labelling and packaging (CLP) and 67.8% of the responders were unaware of any changes made in the labeling of the products they were using. …”
Publicado 2018
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1737por Wang, Yongzhi, Luo, Lingtao, Braun, Oscar Ö, Westman, Johannes, Madhi, Raed, Herwald, Heiko, Mörgelin, Matthias, Thorlacius, Henrik“…Cecal ligation and puncture (CLP)-induced TG in vivo was reflected by a reduced capacity of plasma from septic animals to generate thrombin. …”
Publicado 2018
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1738por Hu, Qiongyuan, Ren, Jianan, Ren, Huajian, Wu, Jie, Wu, Xiuwen, Liu, Song, Wang, Gefei, Gu, Guosheng, Guo, Kun, Li, Jieshou“…Additionally, cecal ligation and puncture (CLP) was established in rats to evaluate the association between UmtDNA and mitochondrial function. …”
Publicado 2018
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1739por Frohnmeyer, Esther, Deptula, Paulina, Nyman, Tuula A., Laine, Pia K. S., Vihinen, Helena, Paulin, Lars, Auvinen, Petri, Jokitalo, Eija, Piironen, Vieno, Varmanen, Pekka, Savijoki, Kirsi“…One of the dairy strains (JS22), producing non‐covalently bound surface‐proteins (LspA, ClpB, AraI) and releasing SlpA and InlA into the culture medium, was found to form clumps under physiological conditions. …”
Publicado 2018
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1740por Xu, Xiaolong, Liu, Qingquan, He, Shasha, Zhao, Jingxia, Wang, Ning, Han, Xuyang, Guo, Yuhong“…The present study aimed to investigate the effect of Qiang-Xin 1 (QX1) formula, a traditional Chinese herbal medicine designed for cardiac dysfunction, on cecal ligation puncture (CLP)-induced heart damage and its underlying mechanisms in mice. …”
Publicado 2018
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