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  1. 1901
    “…In WT plants, but not in cfbp1 plants, small fungal VCs reduced the levels of both transcripts and proteins of the stromal Clp protease system and enhanced those of plastidial chaperonins and co-chaperonins. …”
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    Proteostatic Regulation of MEP and Shikimate Pathways by Redox-Activated Photosynthesis Signaling in Plants Exposed to Small Fungal Volatiles
  2. 1902
    “…Cecal ligation and puncture (CLP) was utilized to establish septic lung injury model in rats. …”
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    Exosomes Derived From Alveolar Epithelial Cells Promote Alveolar Macrophage Activation Mediated by miR-92a-3p in Sepsis-Induced Acute Lung Injury
  3. 1903
    “…Next, plasma desHMGB1 levels were examined in a cecal ligation and puncture (CLP)-induced septic mouse model treated with rTM. …”
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    Specific detection of high mobility group box 1 degradation product with a novel ELISA
  4. 1904
    “…F-AgÅPs potently reduced bacterial burden, reversed dysregulated inflammation, and enhanced survival in mice with CLP- or E. coli bloodstream infection-induced sepsis, either alone or combined with antibiotic therapy. …”
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    Fructose-coated Ångstrom silver prevents sepsis by killing bacteria and attenuating bacterial toxin-induced injuries
  5. 1905
    “…The deletion of sHsp20, clpK(GI), sHsp(GI), pscA, pscB, and hdeD(GI) reduced both heat and chlorine resistance; deletion of kefB reduced only chlorine resistance. …”
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    Ecology and Function of the Transmissible Locus of Stress Tolerance in Escherichia coli and Plant-Associated Enterobacteriaceae
  6. 1906
    “…The current study was designed to explore the role of EPCs derived EVs transmitting TUG1 in macrophage polarization and macrophage-mediated inflammation in a cecal ligation and puncture (CLP)-induced sepsis mouse model. TUG1 was underexpressed in CLP-induced sepsis, and its reexpression induced anti-inflammatory macrophage polarization and suppressed macrophage-medicated inflammatory injury to the pulmonary vascular endothelium. …”
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    Functional delivery of lncRNA TUG1 by endothelial progenitor cells derived extracellular vesicles confers anti-inflammatory macrophage polarization in sepsis via impairing miR-9-5p-targeted SIRT1 inhibition
  7. 1907
    “…Next, we designed de-escalation and escalation strategy in cecum ligation and puncture (CLP) models. Organ injury, inflammatory cytokines, NETs levels were compared and evaluated. …”
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    De-escalation antibiotic therapy alleviates organ injury through modulation of NETs formation during sepsis
  8. 1908
    “…BACKGROUND: Treatment of cleft lip and palate (CLP) requires a comprehensive interdisciplinary approach and long-term follow-up. …”
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    Long-term follow-up of mandibular dental arch changes in patients with complete non-syndromic unilateral cleft lip, alveolus, and palate
  9. 1909
    “…MIF and pyroptosis-related proteins were up-regulated in kidney tissue of mice with CLP (cecum ligation puncture) surgery and in LPS-injured human kidney-2 (HK-2) cells. …”
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    Downregulation of macrophage migration inhibitory factor attenuates NLRP3 inflammasome mediated pyroptosis in sepsis-induced AKI
  10. 1910
    “…The study evaluated the epigenetic alterations and the effects of the environmental enrichment (EE) protocol in the brain of animals submitted to sepsis by cecal ligation and perforation (CLP). Male Wistar rats were divided into sham and CLP at 24 h, 72 h, 10 days and 30 days after sepsis. …”
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    Enriched environment causes epigenetic changes in hippocampus and improves long-term cognitive function in sepsis
  11. 1911
    “…METHODS: C57BL/6 mice underwent cecal ligation and puncture (CLP) surgery to establish sepsis model in vivo. …”
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    Inhibition of visfatin alleviates sepsis-induced intestinal damage by inhibiting Hippo signaling pathway
  12. 1912
    “…ST5 and ST121 had the three genes clpL, mdrL, and lde; however, ST120 and ST2 had two genes except for clpL. …”
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    Persistence of Listeria monocytogenes ST5 in Ready-to-Eat Food Processing Environment
  13. 1913
    “…RESULTS: The number of patients admitted to the surgery ward was significantly higher in the PCP cohort compared to the CLP and PLP cohorts (p = 0.009), with a 42.1% and 37% decline in patients’ admissions, respectively. …”
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    The impact of partial and complete lockdown during the COVID-19 pandemic on acute surgical services: a retrospective cohort study
  14. 1914
    “…Furthermore, the clpV3 mutation led to an increase in the intracellular free Fe(2+) content of P. aeruginosa. …”
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    Pseudomonas aeruginosa H3-T6SS Combats H(2)O(2) Stress by Diminishing the Amount of Intracellular Unincorporated Iron in a Dps-Dependent Manner and Inhibiting the Synthesis of PQS
  15. 1915
    “…METHODS: Cecal ligation and puncture (CLP) surgery and lipopolysaccharide (LPS) treatment were used as in vivo and in vitro sepsis models, respectively. …”
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    PINK1 protects against dendritic cell dysfunction during sepsis through the regulation of mitochondrial quality control
  16. 1916
    “…In rodents following cecal ligation and puncture (CLP), which induces polymicrobial sepsis, in vivo blockade of C5a using neutralizing antibodies dramatically improved survival, reduced apoptosis of lymphoid cells, and attenuated the ensuing coagulopathy. …”
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    Manipulation of the Complement System for Benefit in Sepsis
  17. 1917
    “…This review summarizes the current state of knowledge about the interaction of antitoxins with cellular proteases Lon and ClpP to mediate TA module activation. An understanding of these processes can answer long-standing questions regarding stochastic versus specific activation of TA modules and provide insight into the potential for manipulation of TA modules to alter bacterial growth.…”
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    Toxin-Antitoxin Modules Are Pliable Switches Activated by Multiple Protease Pathways
  18. 1918
    “…This review highlights recent research centred upon a number of potential therapeutic targets from Mab (Ag85C, ClpC1, GyrB, MmpL3 and TrmD), and discusses the various approaches used to discover small molecule inhibitors, in the search for future antibiotics for the treatment of Mab infections.…”
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    Potential therapeutic targets from Mycobacterium abscessus (Mab): recently reported efforts towards the discovery of novel antibacterial agents to treat Mab infections
  19. 1919
    por Cui, Ming, Oestreich, Martin
    Publicado 2021
    “…Trapping the intermediate enolate with ClP(O)(OPh)(2) affords silylated enol phosphates that can be further engaged in Kumada cross‐coupling reactions to yield silylated cyclobutene derivatives.…”
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    Synthesis of Silylated Cyclobutanone and Cyclobutene Derivatives Involving 1,4‐Addition of Zinc‐Based Silicon Nucleophiles
  20. 1920
    “…METHODS: To explore its specific mechanism, we firstly established a sepsis animal model using cecal ligation and puncture (CLP) and treated MH-S cells with LPS plus ATP. Then, UPLC/Q-TOF–MS/MS was utilized to identify its active ingredients. …”
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    Shengjiang San alleviated sepsis-induced lung injury through its bidirectional regulatory effect
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