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Mostrando 201 - 220 Resultados de 341 Para Buscar '"CMG"', tiempo de consulta: 0.80s Limitar resultados
  1. 201
    “…The existence of multiple CMG isolates with high DNA genome diversity in Tanzania and the molecular forces behind this diversity pose a threat to cassava production throughout the African continent.…”
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    Molecular biodiversity of cassava begomoviruses in Tanzania: evolution of cassava geminiviruses in Africa and evidence for East Africa being a center of diversity of cassava geminiviruses
  2. 202
    por Cavazza, Marina
    Publicado 2022
    “…Opening ceremony of the United Kingdom of Great Britain and Northern Ireland Industrial Days, UK@CERN with His Excellency Mr Simon Manley CMG, Ambassador, Permanent Representative of the United Kingdom of Great Britain and Northern Ireland to the United Nations Office and other international organisations in Geneva.…”
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    Visit of Ambassador Simon Manley, Permanent Representative of the UK to the UNOG at opening ceremony of UK@CERN industrial days
  3. 203
    “…Two activators, Cdc45 and GINS, associate with Mcm2-7 at origins of replication to form the CMG complex, which is the active eukaryotic replicative helicase. …”
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    Initiation-specific alleles of the Cdc45 helicase-activating protein
  4. 204
    “…Here we show that Ctf4 tightly dimerizes CMG helicase, with an extensive interface involving Psf2, Cdc45, and Sld5. …”
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    Ctf4 organizes sister replisomes and Pol α into a replication factory
  5. 205
    “…AARPs and leukocytes do not express high levels of the toxin receptors, tumor endothelium marker-8 (TEM8) and capillary morphogenesis protein-2 (CMG2). Less than 20% expressed surface TEM8, while less than 15% expressed CMG2. …”
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    Anthrax Edema and Lethal Toxins Differentially Target Human Lung and Blood Phagocytes
  6. 206
    “…Moreover, we investigated the phenotype of sympathetic trunk ganglia (STG) and caudal mesenteric ganglia (CMG) neurons positive to FB (FB+) by coupling retrograde tracing and double-labeling immunofluorescence methods. …”
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    Localization of Peripheral Autonomic Neurons Innervating the Boar Urinary Bladder Trigone and Neurochemical Features of the Sympathetic Component
  7. 207
    “…Through RNAi-based suppressor screens of lrr-1(0) and cul-2(or209ts) mutants, we identified two genes encoding components of the GINS complex, which is part of the Cdc45-MCM-GINS (CMG) replicative helicase, as well as CDC-7 and MUS-101, which drives the assembly of the CMG helicase during DNA replication. …”
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    RNAi-Based Suppressor Screens Reveal Genetic Interactions Between the CRL2(LRR-1) E3-Ligase and the DNA Replication Machinery in Caenorhabditis elegans
  8. 208
    “…Using single-molecule biochemical assays to monitor CMG formation, we found that Cdc45 and GINS are recruited to loaded Mcm2-7 in two stages. …”
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    DDK regulates replication initiation by controlling the multiplicity of Cdc45-GINS binding to Mcm2-7
  9. 209
    “…Trp346 is of particular interest because of its proximity to the CMG2 binding interface, and because it forms part of the membrane-spanning pore. …”
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    (19)F Nuclear Magnetic Resonance and Crystallographic Studies of 5-Fluorotryptophan-Labeled Anthrax Protective Antigen and Effects of the Receptor on Stability
  10. 210
    “…The most significantly mutated CMG is DNAAF1 with biallelic inactivation and loss of DNAAF1 expression shown in tumours from carriers. …”
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    Rare disruptive mutations in ciliary function genes contribute to testicular cancer susceptibility
  11. 211
    “…Loss of the checkpoint did not regulate the progression and stalling of the CMG complex but rather resulted in the disruption of chromatin at both early and late origins. …”
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    Disruption of origin chromatin structure by helicase activation in the absence of DNA replication
  12. 212
    por Sasso-Cerri, Estela, Cerri, Paulo S
    Publicado 2008
    “…Ten animals were distributed into two groups, control (CG) and cimetidine (CmG) which received saline solution and 50 mg of cimetidine per kg of body weight, respectively, for 52 days. …”
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    Morphological evidences indicate that the interference of cimetidine on the peritubular components is responsible for detachment and apoptosis of Sertoli cells
  13. 213
    “…In S-phase, Dbf4-dependent kinase (DDK) and cyclin-dependent-kinase (CDK) direct with the help of a large number of helicase-activation factors the assembly of a Cdc45–MCM2–7–GINS (CMG) complex. However, in the absence of S-phase kinases complex assembly is inhibited, which is unexpected, as the MCM2–7 double-hexamer represents a very large interaction surface. …”
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    A reconstituted system reveals how activating and inhibitory interactions control DDK dependent assembly of the eukaryotic replicative helicase
  14. 214
    “…Interestingly, Cmg1 localizes to the cytoplasm and to the intermembrane space of mitochondria and its overexpression promotes apoptosis. …”
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    Protein cofactor competition regulates the action of a multifunctional RNA helicase in different pathways
  15. 215
    “…Furthermore, addition of artificial nucleotide Benzi was required for full-length DNA synthesis during bypass of O(6)-CMG. Selective incorporation of the artificial nucleotide opposite an O(6)-alkylguanine DNA adduct was verified using a novel 2′,3′-dideoxy derivative of BenziTP. …”
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    The use of an artificial nucleotide for polymerase-based recognition of carcinogenic O(6)-alkylguanine DNA adducts
  16. 216
    “…In the eukaryotic replicative helicase complex, Cdc45 forms a complex with MCM and GINS, named as CMG (Cdc45-MCM-GINS). Cdc45 shares sequence similarity with bacterial RecJ. …”
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    The Cdc45/RecJ-like protein forms a complex with GINS and MCM, and is important for DNA replication in Thermococcus kodakarensis
  17. 217
    “…RESULTS: CMG identified ten high-priority CFIR constructs as important for genomic medicine. …”
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    Developing a Common Framework for Evaluating the Implementation of Genomic Medicine Interventions in Clinical Care: The IGNITE Network’s Common Measures Working Group
  18. 218
    “…Knockdown of MINA53 reduced the CMG genes expression and thus induced DNA replication stress and DNA damage. …”
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    MINA53 deficiency leads to glioblastoma cell apoptosis via inducing DNA replication stress and diminishing DNA damage response
  19. 219
    “…In this setting, short ubiquitin chains recruit NEIL3 through direct binding, whereas longer chains are required for CMG unloading by the p97 ATPase, enabling the FA pathway. …”
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    TRAIP is a master regulator of DNA interstrand cross-link repair
  20. 220
    “…Cystometric measurements were used for this analysis and were further elaborated as external urethral sphincter electromyographic (EUS-EMG) activity and cystometrogram (CMG) measurements. Moreover, magnetic resonance imaging (MRI) studies were conducted to investigate secondary injury progression in TBI rats, and results were compared to normal control (NC) rats. …”
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    Cystometric Measurements in Rats with an Experimentally Induced Traumatic Brain Injury and Voiding Dysfunction: A Time-Course Study
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