“…Dorsal root ganglia (DRG), SCG, caudal mesenteric ganglion (CMG), pelvic plexus ganglia and spinal cord ventral horns were collected and examined for dye-labeled neuronal cell bodies. …”
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“…BACKGROUND: Hyaline fibromatosis syndrome is a rare progressive autosomal recessive connective tissue disorder caused by a mutation in the ANTXR2/CMG2 gene. According to its severity, patients may present with skin nodules or visceral infiltration, which carries a poor prognosis. …”
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“…CMG recordings were analyzed for the first and the continuous voiding cycles, respectively. …”
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“…In eukaryotes, the replicative helicase is the large multisubunit CMG complex consisting of the Mcm2–7 hexameric ring, Cdc45, and the tetrameric GINS complex. …”
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“…Mortality was 3.5% (O/E ratio 0.74) in the CMG and stroke rate 2.3%. The conversion and bleeding rates were 4.6% each, respectively. …”
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“…We show that DNA synthesis does not slow detectably as forks approach each other and that leading strands pass each other unhindered before undergoing ligation to downstream lagging strands. Dissociation of CMG helicases occurs only after the final ligation step, and is not required for completion of DNA synthesis, strongly suggesting that converging CMGs pass one another and dissociate from double-stranded DNA. …”
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“…In this issue of Genes & Development, Dewar and colleagues (pp. 275–290) identified an E3 ubiquitin ligase, CUL2(LRR2), that modifies a subunit of the replicative CMG (Cdc45, minichromosome maintenance [MCM] subunits 2–7, and the GINS complex) helicase and triggers disassembly of the replication machinery. …”
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“…VMG individuals will perform exercises of the same duration over the same time frame but only in a virtual environment. CMG individuals will hold a weekly session in a real environment and another weekly session in virtual environment. …”
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“…The work assigned to me during this summer (from June 19th to August 11th) was in the "Search for Top in TOTEM" project, a CMG project in collaboration with TOTEM, under the supervision of Martijn Mulders and Laurent Forthomme. …”
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“…The disease is caused by mutations in ANTXR2 also known as the CMG2 gene, which encodes the transmembrane-extracellular matrix assembly. …”
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“…Upon replication initiation, the CDC-45-MCM-GINS (CMG) DNA helicase drives the release of condensin I complexes from chromatin and the activation or displacement of inactive MCM-2–7 complexes, which together with the nucleoporin MEL-28/ELYS tethers condensed chromatin to the nuclear envelope, thereby promoting chromatin decondensation. …”
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“…In this contribution, we present a computational tool called the Concrete Mesostructure Generator (CMG) for the generation of ultra-realistic virtual concrete morphologies for mesoscale and multiscale computational modelling and the simulation of concrete. …”
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“…Alkylated chemically modified graphene (CMG-R) was synthesized to reduce the surface hydrophilicity of graphene and increase compatibility with the PP matrix. …”
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“…PA binds to cells via one of two receptors, TEM8 and CMG2. Interestingly, the toxin times and triggers its own endocytosis, in particular through the heptamerization of PA. …”
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“…ABBREVIATIONS: CDK2 - cyclin-dependent kinase 2, OLO - Olomoucine, NW1 - Cyclohexylmethyloxy-5-Nitroso-Pyrimidine- 2, 4-Diamine, CMG - 6-O-Cyclohexylmethyl Guanine.…”
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“…When only one fork reaches the ICL, the replicative CMG helicase fails to unload from the stalled fork, and repair is blocked. …”
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“…JHF is a relatively mild presentation of the hyaline fibromatosis syndrome (HFS) family of diseases, with Infantile hyaline fibromatosis (IHF) being the more lethal form. A mutation of the (CMG2) gene on chromosome 4q21 is hypothesized to result in the abnormal deposition of amorphous hyaline substance in different body tissues. …”
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“…The rats were divided into five groups and each group was chronically treated with different sets of three immunosuppressive drugs (TRG, CRG, MRG, CMG, TMG) for 6 months. The changes were most profound in calcineurin inhibitor-based protocols. …”
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“…In this work, combustion tube experiments combined with numerical simulations by CMG-STARS were conducted to study the influence of a reservoir′s physical parameters on the stability of ISC. …”
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“…Results obtained from the combustion model were then validated against results obtained from thermal reservoir simulator CMG STARS. Results from the model reveal an upward trending sinusoidal relationship between steam-carbon ratio and the amount of hydrogen yield from an in situ hydrogen production study. …”
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