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  1. 41
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    Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase
  2. 42
    por Langston, Lance, O’Donnell, Mike
    Publicado 2017
    “…We examined the effect of blocks on the eukaryotic CMG and, contrary to expectations, blocks on either strand inhibit CMG unwinding. …”
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    Action of CMG with strand-specific DNA blocks supports an internal unwinding mode for the eukaryotic replicative helicase
  3. 43
    “…Here we show that CMG2 is an important regulator of collagen VI homoeostasis. …”
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    CMG2/ANTXR2 regulates extracellular collagen VI which accumulates in hyaline fibromatosis syndrome
  4. 44
    “…Most significantly, Mcm10 enables CMG and the replisome to bypass blocks on the non-tracking DNA strand. …”
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    Mcm10 promotes rapid isomerization of CMG-DNA for replisome bypass of lagging strand DNA blocks
  5. 45
    “…Eukaryotic origin firing depends on assembly of the Cdc45-MCM-GINS (CMG) helicase. A key step is the recruitment of GINS that requires the leading-strand polymerase Pol epsilon, composed of Pol2, Dpb2, Dpb3, Dpb4. …”
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    Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome
  6. 46
    “…Upon addition of E1 and E2 enzymes, together with ubiquitin and ATP, the CMG helicase is ubiquitylated on its Mcm7 subunit. …”
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    In Vitro Reconstitution Defines the Minimal Requirements for Cdc48-Dependent Disassembly of the CMG Helicase in Budding Yeast
  7. 47
    “…CDT1 inhibits DNA synthesis by suppressing CMG helicase at replication forks, and DNA synthesis commences once CDT1 is degraded. …”
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    CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis
  8. 48
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    DNSN-1 recruits GINS for CMG helicase assembly during DNA replication initiation in C. elegans
  9. 49
    “…In worm, frog and mouse cells, CUL2(LRR1) is required to ubiquitylate the MCM7 subunit of the CMG helicase. Here, we show that cullin ligases also drive CMG-MCM7 ubiquitylation in human cells, thereby making the helicase into a substrate for the p97 unfoldase. …”
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    Reconstitution of human CMG helicase ubiquitylation by CUL2(LRR1) and multiple E2 enzymes
  10. 50
    Publicado 1907
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    Twenty-Five Years as a Hospital Secretary: Presentation to Mr. P. J. Michelli, C.M.G.
  11. 51
    “…Mutation of K29 abrogates in vitro recruitment of Ufd1-Npl4-Cdc48 to the CMG helicase, supporting a model whereby Ufd1-Npl4 recruits Cdc48 to ubiquitylated CMG at the end of chromosome replication, thereby driving the disassembly reaction.…”
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    Ufd1-Npl4 Recruit Cdc48 for Disassembly of Ubiquitylated CMG Helicase at the End of Chromosome Replication
  12. 52
    “…The protein-protein interaction between the human CMG2 receptor and the Bacillus anthracis protective antigen (PA) is essential for the transport of anthrax lethal and edema toxins into human cells. …”
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    Targeting Bacillus anthracis toxicity with a genetically selected inhibitor of the PA/CMG2 protein-protein interaction
  13. 53
    “…The CMG complex (Cdc45, Mcm2–7, GINS (Psf1, 2, 3, and Sld5)) is crucial for both DNA replication initiation and fork progression. …”
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    Recombination and Pol ζ Rescue Defective DNA Replication upon Impaired CMG Helicase—Pol ε Interaction
  14. 54
    “…The eukaryotic replisome is disassembled in each cell cycle, dependent upon ubiquitylation of the CMG helicase. Studies of Saccharomyces cerevisiae, Caenorhabditis elegans and Xenopus laevis have revealed surprising evolutionary diversity in the ubiquitin ligases that control CMG ubiquitylation, but regulated disassembly of the mammalian replisome has yet to be explored. …”
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    CUL2(LRR1), TRAIP and p97 control CMG helicase disassembly in the mammalian cell cycle
  15. 55
    “…We find here that CMG does hydrolyze ATPγS and couples it to DNA unwinding. …”
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    CMG helicase can use ATPγS to unwind DNA: Implications for the rate-limiting step in the reaction mechanism
  16. 56
    por García Santiago, Griselda
    Publicado 2012
    Tesis Libro
    "Monitoreo inalámbrico en banda libre de un sismómetro de banda ancha guralp CMG-6TD" /
  17. 57
    por Cui, Peiling, Yan, Ning
    Publicado 2012
    “…The magnetically suspended Control Moment Gyroscope (CMG) has the advantages of long-life, micro-vibration and being non-lubricating, and is the ideal actuator for agile maneuver satellite attitude control. …”
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    Research on Modeling of the Agile Satellite Using a Single Gimbal Magnetically Suspended CMG and the Disturbance Feedforward Compensation for Rotors
  18. 58
    “…Whereas PolD stably connects primase to GINS, a component of CMG helicase, cryo-EM analysis indicated a highly flexible PolD–primase complex. …”
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    DNA polymerase D temporarily connects primase to the CMG-like helicase before interacting with proliferating cell nuclear antigen
  19. 59
    “…MCM is activated by two proteins, Cdc45 and GINS, which constitute the ‘CMG’ unwindosome complex together with the MCM core. …”
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    Atomic structure of an archaeal GAN suggests its dual roles as an exonuclease in DNA repair and a CMG component in DNA replication
  20. 60
    por Poynter, F. N. L.
    Publicado 1970
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    A Bibliography of Sir Philip Manson-Bahr, C.M.G., D.S.O., M.D., F.R.C.P
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