“…The GINS complex associates with cell division cycle (Cdc) protein 45 and mini‐chromosome maintenance (Mcm) proteins 2–7 to form the Cdc45–Mcm–GINS (CMG) complex, which is essential for DNA duplication. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The CMG2-Fc N-glycan profile was determined using LC-MS/MS with a targeted dynamic multiple reaction monitoring (MRM) method. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Following exercise intervention, the pulmonary function and diaphragm contractility of the CEG rats were significantly improved compared with those of the CMG rats. A total of 36 different metabolites were identified in the comparison between the CMG and the CG. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…To uncover the biosynthetic potential of A. affinis CMG 70, an untargeted metabolomics (LC-MS/MS) approach was used. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…OBJECTIVES: To evaluate the long-term outcome of tacrolimus for childhood-onset myasthenia gravis (CMG) with an inadequate response to glucocorticoids, and investigate factors associated with favorable outcomes following tacrolimus treatment. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We also show that after initiation, Mcm2-7 associate with Cdc45 and GINS to form a relatively stable CMG (Cdc45-MCM-GINS) complex. The CMG proteins also associate less strongly with other replication proteins, consistent with the idea that a single CMG complex forms the core of the replisome.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Control moment gyroscopes (CMG) are crucial components in spacecrafts. Since the anomaly of bearing temperature of the CMG shows apparent correlation with nearly all critical fault modes, temperature prediction is of great importance for health management of CMGs. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We have determined a 3.2 Å cryo‐EM structure of a human replisome comprising CMG, Pol ε, TIMELESS‐TIPIN, CLASPIN and AND‐1 bound to replication fork DNA. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Cost and output data of genetic testing services provided by the CMG during 2014 to 2018 and published literature reviews were applied to estimate the costs and benefits. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…When vertebrate replisomes from neighboring origins converge, the Mcm7 subunit of the replicative helicase, CMG, is ubiquitylated by the E3 ubiquitin ligase, CRL2(Lrr1). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Using VA pharmacy records, we utilized a continuous multiple-interval measure of medication gaps (CMG) to assess the proportion of time in prior year that patient did not possess the prescribed medications; CMG ≥20% is considered clinically significant non-adherence. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Each of the three individual components of the CMG complex (Cdc45, MCM and GINS) is essential for chromosomal DNA replication in eukaryotic cells, both for the initiation of replication at origins and also for normal replication fork progression. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The Cdc45-MCM-GINS (CMG) helicase unwinds DNA during the elongation step of eukaryotic genome duplication and this process depends on the MCM ATPase function. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…A key process in replisome disassembly is the unloading of CMG helicases (CDC45–MCM–GINS), which is initiated in Caenorhabditis elegans and Xenopus laevis by the E3 ubiquitin ligase CRL2(LRR1). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Over the last years several Cognitive Mobile Games (CMG) have been developed to train and challenge the brain. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The overexpression of ERbeta in the germ cells of CmG could be related to a possible interference of cimetidine on tubular androgenization and/or on the intratubular aromatase due to Sertoli cell damage. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…First, the replicative helicase composed of Cdc45, MCM2-7 and GINS (CMG) stalls at a leading strand G4 structure. Second, the DEAH-box helicase 36 (DHX36) mediates bypass of the CMG past the intact G4 structure, allowing approach of the leading strand to the G4. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Two distinct cellular receptors for anthrax toxin, TEM8/ANTXR1 and CMG2/ANTXR2, have been identified, and it is known that their extracellular domains bind PA with low and high affinities, respectively. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Chios mastic gum (CMG), a resin derived from Pistacia lentiscus var. chia, is known since ancient times for its pharmacological activities. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso