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21por Shao, Xueting, Qian, Yun, Xu, Chenhuai, Hong, Bo, Xu, Wanhong, Shen, Ling, Jin, Changzhong, Wu, Zhigang, Tong, Xiangmin, Yao, Hangping“…BACKGROUND: Concanavalin A (ConA)-induced hepatitis is an experimental murine model mirroring the pathology of human autoimmune hepatitis. …”
Publicado 2013
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22“…ConA (20 mg/kg) was injected through vena caudalis in ConA treatment group; the controls received the same volume of saline injection. …”
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23por Kim, Hae-Rim, Park, Mi-Kyung, Cho, Mi-La, Kim, Kyoung-Woon, Oh, Hye-Joa, Park, Jin-Sil, Heo, Yang-Mi, Lee, Sang-Heon, Kim, Ho-Youn, Park, Sung-Hwan“…METHODS: Human RA synovial fibroblasts were treated with concanavalin A (ConA), various cytokines, and inhibitors of signal transduction molecules. …”
Publicado 2010
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24por Zhu, Siran, Choudhury, Nila Roy, Rooney, Saul, Pham, Nhan T, Koszela, Joanna, Kelly, David, Spanos, Christos, Rappsilber, Juri, Auer, Manfred, Michlewski, Gracjan“…Here, we developed a fluorescent on-bead screening platform, RNA Pull-Down COnfocal NAnoscanning (RP-CONA), to identify RNA–protein interaction modulators in eukaryotic cell extracts. …”
Publicado 2021
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25por Fonseca, Victor Juno Alencar, Braga, Ana Lays, de Almeida, Ray Silva, da Silva, Taís Gusmão, da Silva, Josefa Carolaine Pereira, de Lima, Luciene Ferreira, dos Santos, Maria Helena Cruz, dos Santos Silva, Romério Rodrigues, Teixeira, Claudener Souza, Coutinho, Henrique Douglas Melo, Morais-Braga, Maria Flaviana BezerraEnlace del recurso
Publicado 2022
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26por Wu, Yafeng, Ma, Run, Long, Cuizhen, Shu, Yuanhui, He, Ping, Zhou, Yan, Xiang, Yining, Wang, Yuping“…CONCLUSION: Our study suggests that the ConA-induced liver injury model in mice is protected by CB2 agonist AM1241 by modulation of CB2 receptor-rich immune cells, for example, Kupffer cells. …”
Publicado 2021
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27por Chen, Kan, Li, Jingjing, Wang, Junshan, Xia, Yujing, Dai, Weiqi, Wang, Fan, Shen, Miao, Cheng, Ping, Zhang, Yan, Wang, Chengfen, Yang, Jing, Zhu, Rong, Zhang, Huawei, Zheng, Yuanyuan, Lu, Jie, Fan, Zhuoyi, Zhou, Yingqun, Guo, Chuanyong“…In vivo, Balb/C mice were injected with ConA (25 mg/kg) to induce acute autoimmune hepatitis, and 15d-PGJ2 (10 μg or 25 μg) was administered 1 h before the ConA injection. …”
Publicado 2014
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28por Chen, Kan, Li, Jingjing, Wang, Junshan, Xia, Yujing, Dai, Weiqi, Wang, Fan, Shen, Miao, Cheng, Ping, Zhang, Yan, Wang, Chengfen, Yang, Jing, Zhu, Rong, Zhang, Huawei, Zheng, Yuanyuan, Lu, Jie, Fan, Zhuoyi, Zhou, Yingqun, Guo, ChuanyongEnlace del recurso
Publicado 2014
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29por Yang, Wenqian, Shao, Fei, Wang, Jiexin, Shen, Tong, Zhao, Yu, Fu, Xueyan, Zhang, Liming, Li, Hangying“…Purpose: To investigate the effect that ethyl acetate extract of A. argyi (AaEA) on Concanavalin A (ConA)-induced ILI and the mechanism of regulating Bax/Bcl-2 and TLR4/MyD88/NF-κB signaling pathways. …”
Publicado 2022
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30por Camps, Adriano, Bosch-Lluis, Xavier, Ramos-Perez, Isaac, Marchán-Hernández, Juan F., Rodríguez, Nereida, Valencia, Enric, Tarongi, Jose M., Aguasca, Albert, Acevo, René“…At present, two EO space-borne missions are currently planned to be launched in the near future: (1) ESA's SMOS mission, using a Y-shaped synthetic aperture radiometer, launch date November 2nd, 2009, and (2) NASA-CONAE AQUARIUS/SAC-D mission, using a three beam push-broom radiometer. …”
Publicado 2009
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31por Resende, Rafael de Oliveira, Ynoue, Leandro Hideki, Miranda, Juliana Silva, de Almeida, Karine Cristine, Silva, Deise Aparecida de Oliveira, Sopelete, Monica Camargo, Alves, Ronaldo, Gennari-Cardoso, Margareth Leitão, Taketomi, Ernesto Akio“…BACKGROUND: House dust mites are important allergen sources and some of these allergenic proteins may contain carbohydrate moieties, which are able to be isolated using lectins, as Concanavalin A (ConA). This study aimed to investigate allergenicity (IgE) and antigenicity (IgG1 and IgG4) of ConA-unbound and ConA-bound Dermatophagoides pteronyssinus (Dpt) crude extracts using sera of mite-allergic patients as well as inhibition capacity of antibody binding. …”
Publicado 2019
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32“…[Image: see text] Competitive binding assays utilizing concanavalin A (ConA) have the potential to be the basis of improved continuous glucose monitoring devices. …”
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33“…Concanavalin A (ConA), a legume lectin, has been drawing increasing attention in recent years concerning its toxicity against insects and its potential application in pest management. …”
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34“…Concanavalin A (ConA) is a lectin and T-cell mitogen that can activate immune responses. …”
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35por Liu, Tong, Xia, Yujing, Li, Jingjing, Li, Sainan, Feng, Jiao, Wu, Liwei, Zhang, Rong, Xu, Shizan, Cheng, Keran, Zhou, Yuqing, Zhou, Shunfeng, Dai, Weiqi, Chen, Kan, Wang, Fan, Lu, Jie, Zhou, Yingqun, Guo, Chuanyong“…Balb/C mice were exposed to ConA (20 mg/kg) via tail vein injection to establish acute liver injury; shikonin (7.5 mg/kg and 12.5 mg/kg) was intraperitoneally administered 2 h before the ConA injection. …”
Publicado 2016
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36por Feng, Jiao, Niu, Peiqin, Chen, Kan, Wu, Liwei, Liu, Tong, Xu, Shizan, Li, Jingjing, Li, Sainan, Wang, Wenwen, Lu, Xiya, Yu, Qiang, Liu, Ning, Xu, Ling, Wang, Fan, Dai, Weiqi, Xia, Yujing, Fan, Xiaoming, Guo, Chuanyong“…The present study explored the protective effects and the possible mechanisms of Sal on concanavalin A (ConA)-induced liver injury in mice. Balb/C mice were divided into five groups: Normal control (injected with normal saline), ConA (25 mg/kg), Sal (10 mg/kg) +ConA, Sal (20 mg/kg) + ConA (Sal injected 2 h prior to ConA injection) and Sal (20 mg/kg) only. …”
Publicado 2018
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37“…BACKGROUND: It is well established that macrophage infiltration is involved in concanavalin A (conA)-induced liver injury. However, the role of macrophages in conA-induced renal injury remains unknown. …”
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38por Gao, Li, Li, Bin, Wang, Jingyuan, Shen, Danhua, Yang, Min, Sun, Runzi, Tung, Hung‐Chun, Xu, Meishu, Ren, Songrong, Zhang, Min, Yang, Da, Lu, Binfeng, Wang, Hui, Liu, Yulan, Xie, Wen“…In the ConA model, we were surprised to find that activation of LXRα in the constitutively activated VP‐LXRα whole‐body knock‐in (LXRα‐KI) mice exacerbated ConA‐induced AIH, whereas the LXRα(−/−) mice showed attenuated ConA‐induced AIH. …”
Publicado 2020
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39Publicado 1977“…Thymocytes stimulated with ConA do not differentiate to yield cytotoxic effector cells. …”
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40“…Concanavalin A (ConA), a T-cell mitogen that induces acute autoimmune hepatitis, is widely used to model pathophysiological processes of human acute autoimmune liver disease. …”
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