Testis-specific serine kinase protein family in male fertility and as targets for non-hormonal male contraception

por Salicioni, Ana M, Gervasi, María G, Sosnik, Julian, Tourzani, Darya A, Nayyab, Saman, Caraballo, Diego A, Visconti, Pablo E
Publicado 2020

CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or epididymis-enriched genes individually dispensable for male reproduction(†)

por Sun, Jiang, Lu, Yonggang, Nozawa, Kaori, Xu, Zoulan, Morohoshi, Akane, Castaneda, Julio M, Noda, Taichi, Miyata, Haruhiko, Abbasi, Ferheen, Shawki, Hossam H, Takahashi, Satoru, Devlin, Darius J, Yu, Zhifeng, Matzuk, Ryan M, Garcia, Thomas X, Matzuk, Martin M, Ikawa, Masahito
Publicado 2020

The Na(+) and K(+) transport system of sperm (ATP1A4) is essential for male fertility and an attractive target for male contraception

por Syeda, Shameem Sultana, Sánchez, Gladis, McDermott, Jeffrey P, Hong, Kwon Ho, Blanco, Gustavo, Georg, Gunda I
Publicado 2020

The postcoital test in the development of new vaginal contraceptives

por Mauck, Christine K, Vincent, Kathleen L
Publicado 2020

The role of team science in the future of male contraception

por Vahdat, Heather L, Shane, Kevin, Nickels, Logan M
Publicado 2020

Exogenous sex steroids regulate genital epithelial barrier function in female rhesus macaques

por Quispe Calla, Nirk E, Vicetti Miguel, Rodolfo D, Fritts, Linda, Miller, Christopher J, Aceves, Kristen M, Cherpes, Thomas L
Publicado 2020

Prss55 but not Prss51 is required for male fertility in mice

por Kobayashi, Kiyonori, Endo, Tsutomu, Matsumura, Takafumi, Lu, Yonggang, Yu, Zhifeng, Matzuk, Martin M, Ikawa, Masahito
Publicado 2020

CIB4 is essential for the haploid phase of spermatogenesis in mice

por Xu, Zoulan, Miyata, Haruhiko, Kaneda, Yuki, Castaneda, Julio M, Lu, Yonggang, Morohoshi, Akane, Yu, Zhifeng, Matzuk, Martin M, Ikawa, Masahito
Publicado 2020

Engineering monoclonal antibody-based contraception and multipurpose prevention technologies(†)

por Anderson, Deborah J, Politch, Joseph A, Cone, Richard A, Zeitlin, Larry, Lai, Samuel K, Santangelo, Philip J, Moench, Thomas R, Whaley, Kevin J
Publicado 2020

Retinoic acid receptor antagonists for male contraception: current status(†)

por Noman, Md Abdullah Al, Kyzer, Jillian L, Chung, Sanny S W, Wolgemuth, Debra J, Georg, Gunda I
Publicado 2020

Knockout of family with sequence similarity 170 member A (Fam170a) causes male subfertility, while Fam170b is dispensable in mice

por Devlin, Darius J, Nozawa, Kaori, Ikawa, Masahito, Matzuk, Martin M
Publicado 2020

Development of multipurpose technologies products for pregnancy and STI prevention: update on polyphenylene carboxymethylene MPT gel development(†)

por Weitzel, Mary, North, Barbara Best, Waller, Donald
Publicado 2020

Development of WEE2 kinase inhibitors as novel non-hormonal female contraceptives that target meiosis

por Hanna, Carol B, Mudaliar, Deepti, John, Kristen, Allen, C Leigh, Sun, Luxin, Hawkinson, Jon E, Schönbrunn, Ernst, Georg, Gunda I, Jensen, Jeffrey T
Publicado 2020

Towards a roadmap to advance non-hormonal contraceptive multipurpose prevention technologies: strategic insights from key stakeholders(†)

por Hemmerling, Anke, Christopher, Emily, Young Holt, Bethany
Publicado 2020

Filamentous actin disorganization and absence of apical ectoplasmic specialization disassembly during spermiation upon interference with retinoid signaling(†)

por Chung, Sanny S W, Vizcarra, Nika, Wolgemuth, Debra J
Publicado 2020

Metabolism of JQ1, an inhibitor of bromodomain and extra terminal bromodomain proteins, in human and mouse liver microsomes

por Li, Feng, MacKenzie, Kevin R, Jain, Prashi, Santini, Conrad, Young, Damian W, Matzuk, Martin M
Publicado 2020

Mechanism of semen liquefaction and its potential for a novel non-hormonal contraception(†)

por Anamthathmakula, Prashanth, Winuthayanon, Wipawee
Publicado 2020

A cell-based high-content screen identifies isocotoin as a small molecule inhibitor of the meiosis-specific MEIOB–SPATA22 complex(†)

por Xu, Yang, Liu, Rong, Leu, N Adrian, Zhang, Lei, Ibragmova, Ilsiya, Schultz, David C, Wang, P Jeremy
Publicado 2020

Review of rationale and progress toward targeting cyclin-dependent kinase 2 (CDK2) for male contraception(†)

por Faber, Erik B, Wang, Nan, Georg, Gunda I
Publicado 2020

Synthesis of 2-phenyl-5,6,7,8-tetrahydroquinoxaline derivatives and screening for P2X1-purinoceptor antagonist activity in isolated preparations of rat vas deferens, for translatio...

por Mathiew, Mitch, Dennis, Belinda M, Bennetts, Felix, Su, N N Eunice, Nguyen, Nghi, Botteon, Antony, Baell, Jonathan B, Ventura, Sabatino
Publicado 2020