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701por Kathiresan, Nagarajan, Temanni, Ramzi, Almabrazi, Hakeem, Syed, Najeeb, Jithesh, Puthen V., Al-Ali, Rashid“…In-memory computing, vectorization, bulk data transfer, CPU frequency scaling are some of the hardware features in the modern computing architectures. …”
Publicado 2017
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702por Cannella, Nazzareno, Cosa-Linan, Alejandro, Roscher, Mareike, Takahashi, Tatiane T., Vogler, Nils, Wängler, Björn, Spanagel, Rainer“…Specifically, we propose that increased glucose uptake in the CPu and mPFC is a function of controlled drug use, whereas a loss of striatal and prefrontal metabolic activity and reduced uptake in cortical areas are indicative of addictive behavior.…”
Publicado 2017
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703por Valderrama-Carvajal, Alejandra, Irizar, Haritz, Gago, Belén, Jiménez-Urbieta, Haritz, Fuxe, Kjell, Rodríguez-Oroz, María C., Otaegui, David, Rivera, Alicia“…The activation of the dopamine D(4) receptor (D(4)R), which is expressed in the caudate putamen (CPu), mainly counteracts morphine-induced alterations in several molecular networks. …”
Publicado 2018
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704por Xu, Yang, Yang, Tiantian, Zhou, Yao, Yin, Shuangyi, Li, Pengcheng, Liu, Jun, Xu, Shuhui, Yang, Zefeng, Xu, Chenwu“…FASTmrEMMA detected the most QTNs (29), followed by FarmCPU (19) and LASSO (12), GEMMA detected the least QTNs (7). …”
Publicado 2018
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705por Prajapati, Gopal Kumar, Pandey, Bharati, Mishra, Awdhesh Kumar, Baek, Kwang-Hyun, Pandey, Dev Mani“…The GCC-box motif was detected in UR-DEGs (DnaJ and 60S ribosomal protein L7 genes), whereas, the TCC-box was detected in DR-DEGs (DnaK and CPuORF11 genes). In addition, the mechanism of interaction of AP2/EREBP family transcription factor (LOC_Os03g22170) with GCC-box promoter motif present in DnaJ gene (LOC_Os06g09560) and 60S ribosomal protein L7 gene (LOC_Os08g42920); and TCC-box promoter motif of DnaK gene (LOC_Os02g48110) and CPuORF11 gene (LOC_Os02g01240) were explored using molecular dynamics (MD) simulations analysis including binding free energy calculations, principal component analyses, and free energy landscapes. …”
Publicado 2019
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706“…In addition, a series of optimization strategies on both the host CPU side and the MIC side, which includes pre-fetching, optimized communication overlapping scheme, multithreading and hyper-threading, are exploited to improve the execution performance. …”
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707por Bragard, Claude, Dehnen‐Schmutz, Katharina, Di Serio, Francesco, Gonthier, Paolo, Jacques, Marie‐Agnès, Jaques Miret, Josep Anton, Fejer Justesen, Annemarie, MacLeod, Alan, Magnusson, Christer Sven, Navas‐Cortes, Juan A., Parnell, Stephen, Potting, Roel, Reignault, Philippe Lucien, Thulke, Hans‐Hermann, Van der Werf, Wopke, Vicent Civera, Antonio, Yuen, Jonathan, Zappalà, Lucia, Grégoire, Jean‐Claude, Kertész, Virág, Milonas, Panagiotis“…Both nymphs and adults are capable of transmitting CPu and, after acquiring the pathogen, remain infective for the rest of their life. …”
Publicado 2019
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708“…The proton dose calculation algorithm and the conjugate gradient method were tuned for heterogeneous platforms involving the CPU host and GPU device. Three clinical cases — one head and neck cancer case, one lung cancer case, and one prostate cancer case — were investigated to demonstrate the clinical feasibility of the proposed robust optimizer. …”
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709por Phuke, Rahul Madhavrao, He, Xinyao, Juliana, Philomin, Bishnoi, Santosh Kumar, Singh, Gyanendra Pratap, Kabir, Muhammad Rezaul, Roy, Krishna Kanta, Joshi, Arun Kumar, Singh, Ravi Prakash, Singh, Pawan Kumar“…Association mapping was conducted separately for individual experiments and for pooled data using mixed linear model (MLM) and Fixed and random model Circulating Probability Unification (FarmCPU) model; no significant MTAs were recorded through the MLM model, whereas FarmCPU model reported nine significant MTAs located on chromosomes 1B, 2A, 2B, 3B, 4A, 5A, 5B, 6A, and 7D. …”
Publicado 2020
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710por Gao, Guangxiong, Gao, Ning, Li, Sicheng, Kuang, Weijian, Zhu, Lin, Jiang, Wei, Yu, Weiwei, Guo, Jinbiao, Li, Zhili, Yang, Chengzhong, Zhao, Yunxiang“…The genome-wide association study was performed using both fixed and random model Circulating Probability Unification (FarmCPU) and a mixed linear model (MLM) with the rMVP software. …”
Publicado 2021
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711“…Our approach outperforms state-of-the-art implementations by >2 times for the pre-processing stages, creating a scalable and high-performance solution for DeepVariant for both CPU-only and CPU + GPU clusters. CONCLUSIONS: We show the feasibility and easy scalability of our approach to achieve high performance and efficient resource utilization for variant-calling analysis on high-performance computing clusters using the standardized Apache Arrow data representations. …”
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712por Markót, Mihály Csaba“…With the new method the cases [Formula: see text] have been solved in 26, 61, and 13 CPU hours, giving high precision enclosures for all global optimizers and the optimum value. …”
Publicado 2021
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713“…The ST-GWAS models included one single-locus model [mixed-linear model (MLM)] and two multi-locus models [fixed and random model circulating probability unification (FarmCPU) and Bayesian information and linkage-disequilibrium iteratively nested keyway (BLINK)]. …”
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714“…The response time of 14.35 s, throughput of 8592 bytes/s, and central processing unit (CPU) utilization of 22.16% with a strong reliability of service execution is observed. …”
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715por Guo, Zilong, Cao, Hongrui, Zhao, Jing, Bai, Shuang, Peng, Wenting, Li, Jian, Sun, Lili, Chen, Liyu, Lin, Zhihao, Shi, Chen, Yang, Qing, Yang, Yongqing, Wang, Xiurong, Tian, Jiang, Chen, Zhichang, Liao, Hong“…Here, we report a strong association signal at a locus of CPU1 (component of phosphorus uptake 1), from a genome-wide association study of P acquisition efficiency in a soybean core collection grown in the field. …”
Publicado 2022
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716por Nidadavolu, Prakash, Bilkei-Gorzo, Andras, Effah, Felix, Leidmaa, Este, Schürmann, Britta, Berger, Moritz, Bindila, Laura, Schmid, Matthias, Lutz, Beat, Zimmer, Andreas, Bailey, Alexis“…We show that 2-arachidonoylglycerol (2-AG) was prominently decreased in the Hip and moderately in caudate putamen (CPu), whereas anandamide (AEA) was decreased in both CPu and medial prefrontal cortex along with cingulate cortex (mPFC+Cg), starting from 6 months until 12 months. …”
Publicado 2022
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717“…The fast simulation of a high energy physics experiment is a tool used by experimentalists to quickly assess the potentiality of their detectors on a specific analysis or reconstruction tecnique, before imbarking themselves into a more time- and CPU-expensive detailed study with the full simulation. …”
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718“…Since, in general, the more realistic detector description used in full detector simulation causes an unacceptable increase of CPU time consumption when being used in track reconstruction, the reconstruction geometry is realised as a simplified description of the actual detector layout. …”
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719por Sala, Leonardo“…It was observed the default I/O settings for CMS data analysis resulted in poor CPU efficiency and high I/O load at many T2 sites. …”
Publicado 2010
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720“…In this paper the new approach is described and the results for the dynamic aperture are compared with the old approach, including detailed considerations on the CPU-time requirements.…”
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